Results 141 to 150 of about 1,023 (167)

Protodioscin in Dioscorea deltoidea Suspension Cell Culture

Chemistry of Natural Compounds, 2016
One of the main furostanol glycosides in Dioscorea deltoidea suspension cell culture, i.e., protodioscin, was isolated and characterized structurally using NMR spectroscopy, high-resolution mass spectrometry, and an analysis of its accumulation.
A S Shashkov, V Ya Chirva, M T Khandy
exaly   +2 more sources

Effects of Various Asparagus Production Methods on Rutin and Protodioscin Contents in Spears and Cladophylls.

Bioscience, Biotechnology and Biochemistry, 2012
The purpose of this study was to clarify the relationship between various cultivation conditions and the amounts of the rutin (RT) and protodioscin (PD) in asparagus spears. Green and white spears were grown in open culture and under two different blanching conditions.
Tomoo Maeda, Hiroaki Kitazawa, Eiji Nishihara   +2 more
exaly   +3 more sources

Anticonvulsive effects of protodioscin against pilocarpine-induced epilepsy

European Journal of Pharmacology, 2018
Epilepsy is associated with increased morbidity and mortality together and places a large financial burden on individuals and society. To evaluate the anticonvulsant action of protodioscin (PDSN) in experiments with animals with pilocarpine-induced convulsions.
Shiwei, Song, Abul, Fajol, Yan, Chen, Baogang, Ren, Songsheng, Shi   +4 more
openaire   +2 more sources

Methyl Protodioscin Induces G2/M Arrest and Apoptosis in K562 Cells With the Hyperpolarization of Mitochondria

Cancer Letters, 2005
Methyl protodioscin is a furostanol bisglycoside with antitumor properties. The present study investigated its effects on human chronic myelogenous leukemia K562 cells. Cell cycle analysis showed that methyl protodioscin caused distinct G2/M arrest, with the appearance of polyploidy population.
Patrick Ying-Kit Yue, Ricky Ngok-Shun Wong   +1 more
exaly   +3 more sources

The Cytotoxicity of Methyl Protodioscin Against Human Cancer Cell Lines in Vitro

Cancer Investigation, 2003
Methyl protodioscin (NSC-698790) was a furostanol saponin isolated from the rhizome of Dioscorea collettii var. hypoglauca (Dioscoreaceae), a Chinese herbal remedy for the treatment of cervical carcinoma, carcinoma of the urinary bladder, and renal tumors for centuries.
Da-Peng Qin
exaly   +4 more sources

Mathematical models for predicting protodioscin in tropical forage grasses

Toxicon
Protodioscin is a saponin present in grasses that can lead to losses in animal production. Our hypothesis was that mathematical models can accurately and precisely predict the protodioscin concentration in tropical grasses. We evaluated the ability of four mathematical models to describe the protodioscin concentration in Brachiaria and Panicum ...
Juliana Caroline Santos Santana, Gelson dos Santos Difante, Jéssica Gomes Rodrigues, Marislayne de Gusmão Pereira, Henrique Jorge Fernandes, Camila Celeste Brandão Ferreira Ítavo, Vanessa Zirondi Longhini, Alexandre Menezes Dias, Luís Carlos Vinhas Ítavo   +8 more
openaire   +2 more sources

Neuroprotective action and mechanistic evaluation of protodioscin against rat model of Parkinson’s disease

Pharmacological Reports, 2018
Parkinson's disease (PD) is the most widespread motor-affecting disease affecting majorly middle- and late age population. Thus, in the current study, we intended to explore the neuroprotective effect of protodioscin (Proto) against 6-hydroxydopamine (6-OHDA)-induced PD rat model.After induction of PD with the injection of 6-OHDA, the different dose of
Jing, Wu, Yu-Mei, Zhao, Zhi-Kuan, Deng
openaire   +2 more sources

Influence of protodioscin content on digestibility and in vitro degradation kinetics in Urochloa brizantha cultivars

Crop & Pasture Science, 2020
Five cultivars of Urochloa brizantha (Hochst. ex A.Rich.) R.D. Webster (syn. of Brachiaria brizantha) were evaluated for nutritional value and an anti-nutritional factor (protodioscin), in order to determine whether protodioscin content was correlated with reduced feed quality. We evaluated cvv.
Eduardo Souza Leal, Luís Carlos Vinhas Ítavo, Cacilda Borges do Valle, Camila Celeste Brandão Ferreira Ítavo, Alexandre Menezes Dias, Gelson dos Santos Difante, Marcos Barbosa-Ferreira, Lucimara Modesto Nonato, Gleice Kelli Ayardes de Melo, Antonio Leandro Chaves Gurgel   +9 more
openaire   +1 more source

[Determination of plasma protein binding rate of methyl protodioscin with ultrafiltration].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2009
To study the plasma protein binding rate of methyl protodioscin.The ultrafiltration was employed to determine the plasma protein binding rate of methyl protodioscin. The plasma concentrations of methyl protodioscin were measured by HPLC-MS-MS.The plasma protein binding rate of methyl protodioscin with rat plasma at the concentration of 20.0, 100 and ...
Zhi-Hong, Yao, Xiu-Zhen, Cao, Meng, Shao, Yu-Ming, Pan, Wen-Cai, Ye, Xin-Sheng, Yao   +5 more
openaire   +1 more source

Formation of protodioscin and deltoside isomers in suspension cultures of Nepal yam (Dioscorea deltoidea Wall.) cells

Applied Biochemistry and Microbiology, 2016
Changes in the content of the furostanol glycosides protodioscin and deltoside, particularly that of the (25S)-isomers of the glycosides, during suspension cultivation of different lines of Nepal yam (Dioscorea deltoidea Wall.) cells of the strain IFR-DM-0.5 has been investigated. The composition of furostanol glycosides has been characterized, and the
M T, Khandy, M V, Titova, S V, Konstantinova, D V, Kochkin, I M, Ivanov, A M, Nosov   +5 more
openaire   +2 more sources