Results 1 to 10 of about 1,501,856 (330)

Energy efficiency of the high-current diode under the blow-up mode evolution in the anode

Results in Physics, 2023
The results of experimental studies of energy fluxes released during the diode target blow-up initiated by a high-current relativistic electron beam are presented in the paper.
A. Adamenko, V. Novikov, V. Levchenko, V. Prokopenko, A. Shapoval, A. Pashchenko, V. Petukhov, I. Shapoval   +7 more
doaj   +1 more source

Amide proton transfer imaging-arterial spin labeling mismatch: a new imaging biomarker for pilocytic astrocytoma

Scientific Reports, 2023
We describe the potential utility of Amide Proton Transfer weighted (APTw) Magnetic Resonance Imaging and arterial spin labeling (ASL) in characterizing pilocytic astrocytoma (PA), a type of brain tumor that can be challenging to accurately diagnose and ...
Adhithyan Rajendran, Chidambaranathan Natesan, Prashanth Jawahar, Sushama Patil, Srinivas Chilukuri, Siddhartha Ghosh, Roopesh Kumar, Rakesh Jalali   +7 more
doaj   +1 more source

Dose rate and dose robustness for proton transmission FLASH-RT treatment in lung cancer

Frontiers in Oncology, 2022
PurposesTo evaluate the plan quality and robustness of both dose and dose rate of proton pencil beam scanning (PBS) transmission FLASH delivery in lung cancer treatment.Methods and materialsAn in-house FLASH planning platform was used to optimize 10 lung
Shouyi Wei, Haibo Lin, Sheng Huang, Chengyu Shi, Weijun Xiong, Huifang Zhai, Lei Hu, Gang Yu, Robert H. Press, Shaakir Hasan, Arpit M. Chhabra, J. Isabelle Choi, Charles B. Simone, Minglei Kang   +13 more
doaj   +1 more source

Hypofractionated proton beam radiotherapy in patients with unresectable liver tumors: multi-institutional prospective results from the Proton Collaborative Group

Radiation Oncology, 2020
Background Recent advances in radiotherapy techniques have allowed ablative doses to be safely delivered to inoperable liver tumors. In this setting, proton beam radiotherapy (PBT) provides the means to escalate radiation dose to the target volume while ...
Jacob S. Parzen, William Hartsell, John Chang, Smith Apisarnthanarax, Jason Molitoris, Michael Durci, Henry Tsai, James Urbanic, Jonathan Ashman, Carlos Vargas, Craig Stevens, Peyman Kabolizadeh   +11 more
doaj   +1 more source

Preliminary Experience of Treating Children and Young Adults With Image-Guided Proton Beam Therapy in India

JCO Global Oncology, 2020
PURPOSEProton beam therapy (PBT) has been a preferred modality in pediatric malignancies requiring radiotherapy. We report our preliminary experience of treating consecutive patients younger than 25 years with image-guided pencil beam scanning PBT from ...
Srinivas Chilukuri, Nagarjuna Burela, Ramya Uppuluri, D. Indumathi, Sapna Nangia, Pankaj Kumar Panda, Dayananda Sharma Shamurailatpam, Revathi Raj, Thirumalai Raja, Rakesh Jalali   +9 more
doaj   +1 more source

Collective exchange processes reveal an active site proton cage in bacteriorhodopsin [PDF]

, 2020
Proton translocation across membranes is vital to all kingdoms of life. Mechanistically, it relies on characteristic proton flows and modifications of hydrogen bonding patterns, termed protonation dynamics, which can be directly observed by fast magic ...
Brünig, Florian N., Friedrich, Daniel, Hegemann, Peter, Netz, Roland R., Nieuwkoop, Andrew J., Oschkinat, Hartmut   +5 more
core   +1 more source

IMPT of head and neck cancer: unsupervised machine learning treatment planning strategy for reducing radiation dermatitis

Radiation Oncology, 2023
Radiation dermatitis is a major concern in intensity modulated proton therapy (IMPT) for head and neck cancer (HNC) despite its demonstrated superiority over contemporary photon radiotherapy.
Noufal Manthala Padannayil, Dayananda Shamurailatpam Sharma, Sapna Nangia, Kartikeshwar C. Patro, Utpal Gaikwad, Nagarjuna Burela   +5 more
doaj   +1 more source

Prognostic impact of the “Sekhar grading system for cranial Chordomas” in patients treated with pencil beam scanning proton therapy: an institutional analysis

Radiation Oncology, 2020
Background Skull base chordomas are rare and heterogeneously behaving tumors. Though still classified as benign they can grow rapidly, are locally aggressive, and have the potential to metastasize. To adapt the treatment to the specific needs of patients
Anna-Lena Hottinger, Beat Bojaxhiu, Frank Ahlhelm, Marc Walser, Barbara Bachtiary, Stefan Zepter, Tony Lomax, Alessia Pica, Damien C. Weber   +8 more
doaj   +1 more source

Investigating the potential of proton therapy for hypoxia-targeted dose escalation in non-small cell lung cancer

Radiation Oncology, 2021
Background Hypoxia is known to be prevalent in solid tumors such as non-small cell lung cancer (NSCLC) and reportedly correlates with poor prognostic clinical outcome.
Andreas Köthe, Nicola Bizzocchi, Sairos Safai, Antony John Lomax, Damien Charles Weber, Giovanni Fattori   +5 more
doaj   +1 more source

PITChing (professional organisations, innovative trial designs and collaborative approach) for evidence generation for proton therapy

Radiation Oncology, 2020
Developments in the field of proton beam therapy (PBT) have recently crossed the tipping point wherein the modality is now more versatile than ever before, with possibilities and likely indications expanding rapidly.
Srinivas Chilukuri, Pankaj Kumar Panda, Rakesh Jalali   +2 more
doaj   +1 more source