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Amide proton transfer imaging-arterial spin labeling mismatch: a new imaging biomarker for pilocytic astrocytoma

open access: yesScientific Reports, 2023
We describe the potential utility of Amide Proton Transfer weighted (APTw) Magnetic Resonance Imaging and arterial spin labeling (ASL) in characterizing pilocytic astrocytoma (PA), a type of brain tumor that can be challenging to accurately diagnose and ...
Adhithyan Rajendran   +7 more
doaj   +1 more source

Dose rate and dose robustness for proton transmission FLASH-RT treatment in lung cancer

open access: yesFrontiers in Oncology, 2022
PurposesTo evaluate the plan quality and robustness of both dose and dose rate of proton pencil beam scanning (PBS) transmission FLASH delivery in lung cancer treatment.Methods and materialsAn in-house FLASH planning platform was used to optimize 10 lung
Shouyi Wei   +13 more
doaj   +1 more source

Hypofractionated proton beam radiotherapy in patients with unresectable liver tumors: multi-institutional prospective results from the Proton Collaborative Group

open access: yesRadiation Oncology, 2020
Background Recent advances in radiotherapy techniques have allowed ablative doses to be safely delivered to inoperable liver tumors. In this setting, proton beam radiotherapy (PBT) provides the means to escalate radiation dose to the target volume while ...
Jacob S. Parzen   +11 more
doaj   +1 more source

Preliminary Experience of Treating Children and Young Adults With Image-Guided Proton Beam Therapy in India

open access: yesJCO Global Oncology, 2020
PURPOSEProton beam therapy (PBT) has been a preferred modality in pediatric malignancies requiring radiotherapy. We report our preliminary experience of treating consecutive patients younger than 25 years with image-guided pencil beam scanning PBT from ...
Srinivas Chilukuri   +9 more
doaj   +1 more source

Investigating the potential of proton therapy for hypoxia-targeted dose escalation in non-small cell lung cancer

open access: yesRadiation Oncology, 2021
Background Hypoxia is known to be prevalent in solid tumors such as non-small cell lung cancer (NSCLC) and reportedly correlates with poor prognostic clinical outcome.
Andreas Köthe   +5 more
doaj   +1 more source

Prognostic impact of the “Sekhar grading system for cranial Chordomas” in patients treated with pencil beam scanning proton therapy: an institutional analysis

open access: yesRadiation Oncology, 2020
Background Skull base chordomas are rare and heterogeneously behaving tumors. Though still classified as benign they can grow rapidly, are locally aggressive, and have the potential to metastasize. To adapt the treatment to the specific needs of patients
Anna-Lena Hottinger   +8 more
doaj   +1 more source

Encouraging early outcomes with image guided pencil beam proton therapy for cranio-spinal irradiation: first report from India

open access: yesRadiation Oncology, 2022
Background To report our experience with image guided pencil beam proton beam therapy (PBT) for craniospinal irradiation (CSI). Materials and Methods Between January 2019 and December 2021, we carried out a detailed audit of the first forty patients ...
Utpal Gaikwad   +7 more
doaj   +1 more source

Applications of various range shifters for proton pencil beam scanning radiotherapy

open access: yesRadiation Oncology, 2021
Background A range pull-back device, such as a machine-related range shifter (MRS) or a universal patient-related range shifter (UPRS), is needed in pencil beam scanning technique to treat shallow tumors.
Haibo Lin   +11 more
doaj   +1 more source

IMPT of head and neck cancer: unsupervised machine learning treatment planning strategy for reducing radiation dermatitis

open access: yesRadiation Oncology, 2023
Radiation dermatitis is a major concern in intensity modulated proton therapy (IMPT) for head and neck cancer (HNC) despite its demonstrated superiority over contemporary photon radiotherapy.
Noufal Manthala Padannayil   +5 more
doaj   +1 more source

Measurement of the invariant mass distributions for the pp -> ppeta' reaction at excess energy of Q = 16.4 MeV [PDF]

open access: yes, 2010
The proton-proton and proton-eta' invariant mass distributions have been determined for the pp -> ppeta' reaction at an excess energy of Q = 16.4 MeV.
A. Deloff   +52 more
core   +2 more sources

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