Results 101 to 110 of about 2,001,633 (378)

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

open access: yesFEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu   +9 more
wiley   +1 more source

A CGC/saturation approach for angular correlations in proton-proton scattering

open access: yes, 2017
We generalized our model for the description of hard processes, and calculate the value of the azimuthal angle correlations ( Fourier harmonics $v_n$ ), for proton-proton scattering.The energy and multiplicity independence, as well as the value of $v_n$,
Gotsman, E., Levin, E., Potashnikova, I.
core   +1 more source

Uncovering the Scaling Laws of Hard Exclusive Hadronic Processes in a Comprehensive Endpoint Model [PDF]

open access: yes, 2014
We show that an endpoint overlap model can explain the scaling laws observed in exclusive hadronic reactions at large momentum transfer. The model assumes one of the valence quarks carries most of the hadron momentum.
Dagaonkar, Sumeet   +2 more
core   +3 more sources

Proton-Proton Scattering at 340 MeV [PDF]

open access: yesPhysical Review, 1950
Measurements of the proton-proton differential scattering cross section using 340 Mev protons show a cross section approximately constant between 41{sup o} and 90{sup o} in the center of mass system. Two methods of counting the scattered protons have been used. The first method uses a counter telescope to count the scattered protons.
Chamberlain, Owen, Wiegand, Clyde
openaire   +7 more sources

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

open access: yesFEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr   +5 more
wiley   +1 more source

Parity Violation in Proton-Proton Scattering

open access: yes, 1997
Measurements of parity-violating longitudinal analyzing powers (normalized asymmetries) in polarized proton-proton scattering provide a unique window on the interplay between the weak and strong interactions between and within hadrons. Several new proton-
A.A. Green   +61 more
core   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

open access: yesFEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma   +10 more
wiley   +1 more source

Clinical results of proton beam therapy for elderly patients with non-small cell lung cancer

open access: yesRadiation Oncology, 2018
Background The purpose of the present study was to evaluate retrospectively the efficacy and safety of proton beam therapy for elderly patients (≥80 years of age) with non-small cell lung cancer.
Takashi Ono   +9 more
doaj   +1 more source

Structural and functional characterization of chitinase from carnivorous plant Drosera adelae

open access: yesFEBS Open Bio, EarlyView.
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda   +7 more
wiley   +1 more source

Particle Beam Radiation Therapy for Adenoid Cystic Carcinoma of the Nasal Cavity and Paranasal Sinuses

open access: yesFrontiers in Oncology, 2020
Background: Sinonasal adenoid cystic carcinoma (SNACC) presents a challenge to oncologists due to its complex anatomy and poor prognosis. Although radiation therapy, either definitive or adjuvant to surgery, is an important part of the multidisciplinary ...
Weixu Hu   +15 more
doaj   +1 more source

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