Results 71 to 80 of about 1,541,061 (327)
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
First direct observation of two protons in the decay of $^{45}$Fe with a TPC [PDF]
, 2007 The decay of the ground-state two-proton emitter 45Fe was studied with a time-projection chamber and the emission of two protons was unambiguously identified.
B. Blank +19 more
core +4 more sources
High Oxygen Reduction Activity of Pt-Ni Alloy Catalyst for Proton Exchange Membrane Fuel Cells [PDF]
, 2022 Jun Gu +5 more
openalex +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Emission of neutron-proton and proton-proton pairs in electron scattering induced by meson-exchange currents [PDF]
, 2016 We use a relativistic model of meson-exchange currents to compute the proton-neutron and proton-proton yields in $(e,e')$ scattering from $^{12}$C in the 2p-2h channel.
Amaro, J. E. +6 more
core +3 more sources
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Tagging Two-Photon Production at the LHC [PDF]
, 2000 Tagging two-photon production offers a significant extension of the LHC physics programme. Effective luminosity of high-energy gamma-gamma collisions reaches 1% of the proton-proton luminosity and the standard detector techniques used for measuring very ...
D. L. Borden +6 more
core +3 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Dilepton Production in Nucleon-Nucleon Reactions With and Without Hadronic Inelasticities
, 1993 We calculate elementary proton-proton and neutron-proton bremsstrahlung and their contribution to the $e^+e^-$ invariant mass distribution. At 4.9 GeV, the proton-proton contribution is larger than neutron-proton, but it is small compared to recent data.
C. Gale +23 more
core +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source