Results 91 to 100 of about 3,306,946 (213)

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

D‐amino acid oxidase as a chemogenetic tool for spatiotemporally controlled hydrogen peroxide production: The oxygen connection

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose D‐amino acid oxidase (DAO) has been developed as a chemogenetic tool, to precisely manipulate redox levels in tissues and cells by generating H2O2 in the presence of D‐amino acids. The enzyme's significant oxygen consumption during H2O2 production may influence cellular oxygen levels.
Wiebke Maurer, Anke Zieseniss, Vamsi Priya Vikram, Yamin Chen, Laura Bauer, Annette Hillemann, Peter Rehling, Maithily S. Nanadikar, Diane de Zélicourt, Vartan Kurtcuoglu, Dörthe M. Katschinski   +10 more
wiley   +1 more source

Patient-specific quality assurance and plan complexity: from photon standardisation to the unique characteristics of particle therapy

Frontiers in Physics
Patient-specific quality assurance (PSQA) is a safety barrier ensuring that treatment plans calculated by the Treatment Planning System (TPS) are accurately delivered by the machine.
Maxence Rayer, Maxence Rayer, Maxence Rayer, Daniel Maneval, Cyril Moignier, Thomas Tessonnier, Dorothée Lebhertz, Anthony Vela, Gary Delattre, Laetitia Lechippey, Alain Batalla, Aurélien Corroyer-Dulmont, Aurélien Corroyer-Dulmont, Aurélien Corroyer-Dulmont   +13 more
doaj   +1 more source

Do We Really Know How to Manage Anticoagulated Patients for Periodontal Nonsurgical Therapy? An Observational Cohort Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objectives The aim of this work is to assess and compare the impact of direct oral anticoagulants (DOACs) versus vitamin K antagonists (VKA) during and immediately after periodontal nonsurgical therapy. Materials and Methods A prospective observational cohort study was conducted with patients who presented a history of cardiovascular disease ...
F. Berton, A. Rapani, F. Costantinides, V. Nicolin, D. Cuhureanu, R. Di Lenarda   +5 more
wiley   +1 more source

Dosimetric Comparison of Particle Radiotherapy and Photon VMAT for Left-Sided Breast Cancer Post Breast-Conserving Surgery

Technology in Cancer Research & Treatment
Introduction Carbon ion radiotherapy shows potential for left-sided breast cancer, yet comparative dosimetric data remains limited. This study retrospectively compared the dosimetric characteristics of proton and carbon ion radiotherapies with conformal ...
Wenlingjie Huang BM, Runhong Lei PhD, Xiuwen Deng MD, Xiaoyun Ma MS, Ping Jiang MD, Jiaming Wu PhD, Tianye Niu PhD, Wanbin Meng PhD, Yancheng Ye MD, Junjie Wang PhD   +9 more
doaj   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

DoseRAD2026: A benchmark dataset for AI-accelerated photon and proton dose calculation in radiotherapy. [PDF]

Med Phys
Abstract Purpose Accurate dose calculation is a fundamental component of modern radiotherapy, enabling precise tumor irradiation while sparing surrounding healthy tissue. With the increasing adoption of magnetic resonance imaging (MRI)‐guided radiotherapy and growing interest in real‐time adaptive radiotherapy, there is a demand for fast and accurate ...
Xiao F, Delopoulos N, Wahl N, Volz L, Bucher L, Maspero M, Palacios M, Li M, Schulz S, Rogowski V, Zhang Y, Perko Z, Kurz C, Dedes G, Landry G, Thummerer A.   +15 more
europepmc   +2 more sources

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Proton Therapy in Uveal Melanoma [PDF]

Background/Objectives: Uveal melanoma is the most common primary intraocular malignancy in adults. Treatment options for localized, early-stage disease include enucleation, brachytherapy, and proton beam therapy.
Choi, J. Isabelle, Yacoub, Irini, Chan, Adrian Wai, J. Isabelle Choi, Charles B. Simone, Chhabra, Arpit M., Haibo Lin, Irini Yacoub, Adrian Wai Chan, Arpit M. Chhabra, Lin, Haibo, Simone, Charles B.   +11 more
core   +1 more source

Association between proton pump inhibitor therapy and clostridium difficile infection: a contemporary systematic review and meta-analysis. [PDF]

, 2012
Introduction Emerging epidemiological evidence suggests that proton pump inhibitor (PPI) acid-suppression therapy is associated with an increased risk of Clostridium difficile infection (CDI).
Sutton, AJ, Imad M. Tleyjeh (104252), Tannir Mohamad Al, Alex J Sutton, AlGhamdi, M, Muhammad Riaz (104236), Bin Abdulhak, AA, Ibrahim Talal, Mushabab AlGhamdi (112556), Baddour, LM, Alasmari Faisal A., A. A. Bin Abdulhak (7656569), Abed Allehibi, Talal Ibrahim (112568), Allehibi, A., Alasmari, FA, Faisal A. Alasmari (112549), F. A. Alasmari (7656575), A. R. Khan (3951662), AlGhamdi Mushabab, A. AlLehibi (7656593), Khan, AR, Al Tannir, M, Tleyjeh, IM, I. M. Tleyjeh (7656566), AlGhamdi, M., Abed AlLehibi (112573), Khan, A. R., Alex J. Sutton (112577), Garbati Musa A., L. M. Baddour (7656596), Aref A Bin Abdulhak, M. A. Garbati (7656578), M. Al Tannir (7656584), Bin Abdulhak, A. A., M. AlGhamdi (7656581), Erwin, P. J., Imad M Tleyjeh, Khan Abdur Rahman, Tleyjeh, I. M., Patricia J Erwin, T. Ibrahim (7656590), Muhammad Riaz, Abdur Rahman Khan (104234), Garbati, MA, Allehibi, A, Bin Abdulhak Aref A., Erwin, PJ, Sutton Alex J., M. Riaz (7656572), Riaz Muhammad, Musa A Garbati, Alasmari, F. A., Patricia J. Erwin (104246), Talal Ibrahim, Abdur Rahman Khan, Ibrahim, T., Mushabab AlGhamdi, A. J. Sutton (7648487), Faisal A Alasmari, Ibrahim, T, Mohamad Al Tannir (112562), Mohamad Al Tannir, Erwin Patricia J., Larry M Baddour, Baddour Larry M., Al Tannir, M., P. J. Erwin (7656587), Aref A. Bin Abdulhak (104239), Garbati, M. A., Larry M. Baddour (104249), Riaz, Muhammad, Riaz, M, Tleyjeh Imad M., Baddour, L. M., Sutton, A. J., Musa A. Garbati (104244), AlLehibi Abed   +77 more
core   +1 more source