Demonstration of the FLASH Effect Within the Spread-out Bragg Peak After Abdominal Irradiation of Mice [PDF]
Purpose: The effects of FLASH-level dose rates delivered at the spread-out Bragg peak (SOBP) on normal tissue damage in mice were investigated. Materials and Methods: Fifty nontumor-bearing mice received abdominal irradiation, 30 at FLASH dose rates (100
Tucker Evans, BS +4 more
doaj +1 more source
Radiation Exposure of Cardiac Conduction Nodes During Breast Proton Therapy [PDF]
Purpose: The exposition of cardiac conduction system during breast radiation therapy has never been studied, despite the increasing use of intensity-modulated radiation therapy, which exposes larger volume to low-dose bath.
Pierre Loap, MD +5 more
doaj +1 more source
Initial Experience with Proton Beam Therapy for Differentiated Thyroid Cancer [PDF]
Purpose: External beam radiotherapy is used in a subset of high-risk patients with differentiated thyroid cancer (DTC). Recurrent, radioactive iodine (RAI)–refractory DTC carries a poor prognosis.
Nathan Y. Yu, MD +8 more
doaj +1 more source
Work Outcomes after Intensity-Modulated Proton Therapy (IMPT) versus Intensity-Modulated Photon Therapy (IMRT) for Oropharyngeal Cancer [PDF]
Purpose: We compared work outcomes in patients with oropharyngeal cancer (OPC), randomized to intensity-modulated proton (IMPT) versus intensity-modulated photon therapy (IMRT) for chemoradiation therapy (CRT).
Grace L. Smith, MD, PhD, MPH +23 more
doaj +1 more source
Assessment of Knowledge-Based Planning for Prostate Intensity Modulated Proton Therapy [PDF]
Purpose: To assess the performance of a proton-specific knowledge based planning (KBPP) model in creation of robustly optimized intensity-modulated proton therapy (IMPT) plans for treatment of patients with prostate cancer.
Yihang Xu, BS +11 more
doaj +1 more source
Intensity Modulated Proton Therapy for Hepatocellular Carcinoma: Initial Clinical Experience
Purpose: Our purpose was to assess the safety and efficacy of intensity modulated proton therapy (IMPT) for the treatment of hepatocellular carcinoma (HCC). Methods and Materials: A retrospective review was conducted on all patients who were treated with
Ronik S. Bhangoo, MD +15 more
doaj +1 more source
Risk of second primary cancer from proton arc therapy of pediatric brain tumors
Proton arc therapy (PAT) is currently explored for clinical implementation, despite its associated low-dose bath. This study therefore aimed at evaluating the risk of radiation-induced second primary cancer (SPC) for PAT in pediatric brain tumor patients.
Laura Toussaint +3 more
doaj +1 more source
Patient-Reported Outcomes after Intensity-Modulated Proton Therapy for Oropharynx Cancer [PDF]
Purpose: To report patient-reported outcomes (PROs) derived from the Functional Assessment of Cancer Therapy-Head and Neck (FACT-HN) tool, in patients with oropharynx cancer (OPC) treated with intensity-modulated proton therapy (IMPT) in the context of ...
Houda Bahig, MD, PhD +15 more
doaj +1 more source
Treatment planning of total marrow irradiation with intensity-modulated spot-scanning proton therapy
PurposeThe goal of this study is to investigate treatment planning of total marrow irradiation (TMI) using intensity-modulated spot-scanning proton therapy (IMPT).
Darren M. Zuro +8 more
doaj +1 more source
Proton Beam Radiation Therapy for Oropharyngeal Squamous Cell Carcinoma [PDF]
Purpose: To discuss the role of proton beam therapy (PBT) in the treatment of patients with oropharyngeal squamous cell carcinoma (OPSCC). Materials and Methods: A review of the pertinent literature. Results: Proton beam therapy likely results in reduced
William M. Mendenhall, MD +13 more
doaj +1 more source

