Results 1 to 10 of about 4,456,525 (155)

Dosimetric comparison of intensity-modulated proton therapy and proton arc therapy for pediatric ependymoma [PDF]

Acta Oncologica
Background and purpose: Proton Arc Therapy (PAT) is an emerging proton therapy treatment modality with the potential to reduce radiation exposure to healthy tissues compared to conventional Intensity-Modulated Proton Therapy (IMPT) with fewer beams. This
Helge Henjum, Karoline Mo Feten, Erlend Hartvigsen, Kristian S. Ytre-Hauge, Camilla G. Boer, Camilla H. Stokkevåg   +5 more
doaj   +3 more sources

Intensity-modulated proton therapy vs intensity-modulated radiotherapy in nasopharyngeal carcinoma: a case–control studyResearch in context [PDF]

The Lancet Regional Health. Americas
Summary: Background: Intensity-modulated proton therapy (IMPT) is associated with fewer acute toxicities compared with intensity-modulated radiotherapy (IMRT) in definitive treatment of nonmetastatic nasopharyngeal carcinoma (NPC).
Caineng Cao, Teeradon Treechairusame, Amir H. Safavi, Yingzhi Wu, Zhigang Zhang, Achraf Shamseddine, Yao Yu, Nadeem Riaz, Daphna Y. Gelblum, Sean M. McBride, Alan L. Ho, Winston Wong, Lara A. Dunn, Loren Scott Michel, Eric J. Sherman, Nancy Y. Lee   +15 more
doaj   +2 more sources

Clinical implementation of intensity modulated proton therapy for testicular seminoma [PDF]

Acta Oncologica
Background and purpose: We have previously shown that proton therapy results in considerable reduced doses to abdominal organs at risk (OAR) which likely reduces the patient’s risk of a second malignant tumor, which is vital for this young population ...
Heidi S. Rønde, Jesper F. Kallehauge, Morten Høyer, Anne Birgitte Als, Mads Agerbæk, Jakob Lauritsen, Peter M. Petersen, Lars Dysager, Camilla J.S. Kronborg   +8 more
doaj   +2 more sources

Physician- and Patient-Reported Outcomes Following Contemporary Image Guided Intensity Modulated Proton Therapy for Prostate Cancer: Results From the Prospective PRO-Cube Study [PDF]

Advances in Radiation Oncology
Purpose: Multiple prospective studies have established the safety of proton therapy for localized prostate cancer. However, prospective data defining physician-reported adverse events (AEs) and patient-reported outcomes (PROs) with contemporary image ...
Sham Sundar, MD, Srinivas Chilukuri, MD, Manikandan Arjunan, MSc, PhD, Ramakrishna Kamath, MD, Abhilasha Sinha, MD, Mahalakshmi Palani, BSc, Pankaj Kumar Panda, MSc, Sujith K. Mullapally, DM, Srivathsan Ramani, MCh, Narasimhan Ragavan, MCh, Prashant Jawahar, MD, Jaykanth Amalachandran, MD, Dayananda Shamurailatpam Sharma, MSc, PhD, Rakesh Jalali, MD   +13 more
doaj   +2 more sources

Potential normal tissue sparing in vulvar cancer using intensity modulated proton therapy versus volumetric modulated arc therapy [PDF]

Physics and Imaging in Radiation Oncology
Background and purpose: Photon radiotherapy, typically volumetric modulated arc therapy (VMAT), is the standard for adjuvant or definitive treatment of vulvar cancer.
Anna C. Prins, Raymond de Boer, András G. Zolnay, Remi A. Nout, Mischa S. Hoogeman, Kelvin Ng Wei Siang   +5 more
doaj   +2 more sources

Long-Term Patient-Reported Bowel and Urinary Quality of Life in Patients Treated with Intensity-Modulated Radiotherapy Versus Intensity-Modulated Proton Therapy for Localized Prostate Cancer [PDF]

Current Oncology
Purpose: This study aimed to compare long-term patient-reported outcomes in bowel and urinary domains between intensity-modulated radiotherapy (IMRT) and intensity-modulated proton therapy (IMPT) for localized prostate cancer.
Kimberly R. Gergelis, Miao Bai, Jiasen Ma, David M. Routman, Bradley J. Stish, Brian J. Davis, Thomas M. Pisansky, Thomas J. Whitaker, Richard Choo   +8 more
doaj   +2 more sources

Demonstration of the FLASH Effect Within the Spread-out Bragg Peak After Abdominal Irradiation of Mice [PDF]

International Journal of Particle Therapy, 2021
Purpose: The effects of FLASH-level dose rates delivered at the spread-out Bragg peak (SOBP) on normal tissue damage in mice were investigated. Materials and Methods: Fifty nontumor-bearing mice received abdominal irradiation, 30 at FLASH dose rates (100
Tucker Evans, BS, James Cooley, PhD, Miles Wagner, MS, Tianning Yu, PhD, Townsend Zwart, PhD   +4 more
doaj   +1 more source

Radiation Exposure of Cardiac Conduction Nodes During Breast Proton Therapy [PDF]

International Journal of Particle Therapy, 2023
Purpose: The exposition of cardiac conduction system during breast radiation therapy has never been studied, despite the increasing use of intensity-modulated radiation therapy, which exposes larger volume to low-dose bath.
Pierre Loap, MD, Farid Goudjil, PhD, Vincent Servois, MD, Krassen Kirov, MD, Alain Fourquet, MD, Youlia Kirova, MD   +5 more
doaj   +1 more source

Initial Experience with Proton Beam Therapy for Differentiated Thyroid Cancer [PDF]

International Journal of Particle Therapy, 2021
Purpose: External beam radiotherapy is used in a subset of high-risk patients with differentiated thyroid cancer (DTC). Recurrent, radioactive iodine (RAI)–refractory DTC carries a poor prognosis.
Nathan Y. Yu, MD, Aditya Khurana, BS, Daniel J. Ma, MD, Michelle A. Neben-Wittich, MD, Michael A. Golafshar, MS, Lisa A. McGee, MD, Jean-Claude M. Rwigema, MD, Robert L. Foote, MD, Samir H. Patel, MD   +8 more
doaj   +1 more source

Work Outcomes after Intensity-Modulated Proton Therapy (IMPT) versus Intensity-Modulated Photon Therapy (IMRT) for Oropharyngeal Cancer [PDF]

International Journal of Particle Therapy, 2021
Purpose: We compared work outcomes in patients with oropharyngeal cancer (OPC), randomized to intensity-modulated proton (IMPT) versus intensity-modulated photon therapy (IMRT) for chemoradiation therapy (CRT).
Grace L. Smith, MD, PhD, MPH, Shuangshuang Fu, PhD, Matthew S. Ning, MD, MPH, Diem-Khanh Nguyen, BA, Paul M. Busse, MD, PhD, Robert L. Foote, MD, Adam S. Garden, MD, Gary B. Gunn, MD, Clifton D. Fuller, MD, PhD, William H. Morrison, MD, Gregory M. Chronowski, MD, Shalin J. Shah, MD, Lauren L. Mayo, MD, Jack Phan, MD, PhD, Jay P. Reddy, PhD, James W. Snider III, MD, Samir H. Patel, MD, Sanford R. Katz, MD, Alexander Lin, MD, Nasiruddin Mohammed, MD, Roi Dagan, MD, MS, Nancy Y. Lee, MD, David I. Rosenthal, MD, Steven J. Frank, MD   +23 more
doaj   +1 more source