Results 11 to 20 of about 14,370 (210)

Intensity-modulated proton therapy vs intensity-modulated radiotherapy in nasopharyngeal carcinoma: a case–control studyResearch in context [PDF]

The Lancet Regional Health. Americas
Summary: Background: Intensity-modulated proton therapy (IMPT) is associated with fewer acute toxicities compared with intensity-modulated radiotherapy (IMRT) in definitive treatment of nonmetastatic nasopharyngeal carcinoma (NPC).
Caineng Cao, Teeradon Treechairusame, Amir H. Safavi, Yingzhi Wu, Zhigang Zhang, Achraf Shamseddine, Yao Yu, Nadeem Riaz, Daphna Y. Gelblum, Sean M. McBride, Alan L. Ho, Winston Wong, Lara A. Dunn, Loren Scott Michel, Eric J. Sherman, Nancy Y. Lee   +15 more
doaj   +2 more sources

Clinical implementation of intensity modulated proton therapy for testicular seminoma [PDF]

Acta Oncologica
Background and purpose: We have previously shown that proton therapy results in considerable reduced doses to abdominal organs at risk (OAR) which likely reduces the patient’s risk of a second malignant tumor, which is vital for this young population ...
Heidi S. Rønde, Jesper F. Kallehauge, Morten Høyer, Anne Birgitte Als, Mads Agerbæk, Jakob Lauritsen, Peter M. Petersen, Lars Dysager, Camilla J.S. Kronborg   +8 more
doaj   +2 more sources

Physician- and Patient-Reported Outcomes Following Contemporary Image Guided Intensity Modulated Proton Therapy for Prostate Cancer: Results From the Prospective PRO-Cube Study [PDF]

Advances in Radiation Oncology
Purpose: Multiple prospective studies have established the safety of proton therapy for localized prostate cancer. However, prospective data defining physician-reported adverse events (AEs) and patient-reported outcomes (PROs) with contemporary image ...
Sham Sundar, MD, Srinivas Chilukuri, MD, Manikandan Arjunan, MSc, PhD, Ramakrishna Kamath, MD, Abhilasha Sinha, MD, Mahalakshmi Palani, BSc, Pankaj Kumar Panda, MSc, Sujith K. Mullapally, DM, Srivathsan Ramani, MCh, Narasimhan Ragavan, MCh, Prashant Jawahar, MD, Jaykanth Amalachandran, MD, Dayananda Shamurailatpam Sharma, MSc, PhD, Rakesh Jalali, MD   +13 more
doaj   +2 more sources

Potential normal tissue sparing in vulvar cancer using intensity modulated proton therapy versus volumetric modulated arc therapy [PDF]

Physics and Imaging in Radiation Oncology
Background and purpose: Photon radiotherapy, typically volumetric modulated arc therapy (VMAT), is the standard for adjuvant or definitive treatment of vulvar cancer.
Anna C. Prins, Raymond de Boer, András G. Zolnay, Remi A. Nout, Mischa S. Hoogeman, Kelvin Ng Wei Siang   +5 more
doaj   +2 more sources

Dosimetric comparison of intensity-modulated proton therapy and proton arc therapy for pediatric ependymoma [PDF]

Acta Oncologica
Background and purpose: Proton Arc Therapy (PAT) is an emerging proton therapy treatment modality with the potential to reduce radiation exposure to healthy tissues compared to conventional Intensity-Modulated Proton Therapy (IMPT) with fewer beams. This
Helge Henjum, Karoline Mo Feten, Erlend Hartvigsen, Kristian S. Ytre-Hauge, Camilla G. Boer, Camilla H. Stokkevåg   +5 more
doaj   +2 more sources

Long-Term Patient-Reported Bowel and Urinary Quality of Life in Patients Treated with Intensity-Modulated Radiotherapy Versus Intensity-Modulated Proton Therapy for Localized Prostate Cancer [PDF]

Current Oncology
Purpose: This study aimed to compare long-term patient-reported outcomes in bowel and urinary domains between intensity-modulated radiotherapy (IMRT) and intensity-modulated proton therapy (IMPT) for localized prostate cancer.
Kimberly R. Gergelis, Miao Bai, Jiasen Ma, David M. Routman, Bradley J. Stish, Brian J. Davis, Thomas M. Pisansky, Thomas J. Whitaker, Richard Choo   +8 more
doaj   +2 more sources

Clinical Outcomes of Intensity Modulated Proton Therapy Reirradiation for Gynecologic Malignancies

Advances in Radiation Oncology, 2023
Purpose: Pelvic reirradiation (re-RT) for patients with gynecologic cancers remains a challenge because of toxicity concerns. Given the dosimetric advantages of proton therapy, we aimed to assess oncologic and toxicity outcomes of patients with re-RT to ...
Ariel E. Pollock, MD, Hunter Risher, BS, Melanie Berger, MD, Dana M. Roque, MD, Gautam Rao, MD, Elizabeth M. Nichols, MD, Pranshu Mohindra, MD, MMM   +6 more
doaj   +1 more source

A Systematic Review of Proton Therapy for the Management of Nasopharyngeal Cancer [PDF]

International Journal of Particle Therapy, 2021
Purpose: With improved technology, more patients with nasopharyngeal cancer (NPC) are receiving definitive treatment with proton therapy, which allows greater sparing of dose to normal tissues without compromising efficacy. As there is no randomized data,
Anna Lee, MD, MPH, Sarin Kitpanit, MD, Marina Chilov, MLS, Johannes A. Langendijk, MD, PhD, Jiade Lu, MD, MBA, Nancy Y. Lee, MD, FASTRO   +5 more
doaj   +1 more source

A review of proton therapy – Current status and future directions

Precision Radiation Oncology, 2022
The original rationale for proton therapy was its highly conformal depth‐dose distributions compared to photons, which allow greater sparing of normal tissues and escalation of tumor doses, thus potentially improving outcomes.
Radhe Mohan
doaj   +1 more source

A pilot study on the comparison between planning target volume-based intensity-modulated proton therapy plans and robustly optimized intensity-modulated proton therapy plans

Journal of Medical Physics, 2018
The objective of this work is to compare the planning target volume (PTV)-based intensity-modulated proton therapy (IMPT) plans with robustly optimized IMPT plans using the robust optimization tools available in Pinnacle Treatment Planning System.
Bojarajan Perumal, Harikrishna Etti Sundaresan, Ranganathan Vaitheeswaran   +2 more
doaj   +1 more source