Results 121 to 130 of about 20,031 (226)

Proton beam therapy for patients with distal cholangiocarcinoma: a multicenter prospective registry study (Influence of age factor). [PDF]

J Radiat Res
Yamazaki H, Shibuya K, Kimoto T, Suzuki M, Murakami M, Terashima K, Iizumi T, Wakatsuki M, Ogino T, Takagi M, Araya M, Matsumoto S, Ogino H, Hashimoto T, Hojo H, Fukumitsu N, Yanagi T.   +16 more
europepmc   +1 more source

Deep Mutational Scanning for the Study and Engineering of Protein Assemblies

Chemistry–Methods, Volume 6, Issue 8, August 2026.
This review explores how deep mutational scanning (DMS) can be used to improve understanding and accelerate engineering of protein assemblies, from natural fibers to engineered nanocages. We discuss various types of protein assemblies and their characterization, provide an introduction to the DMS technique, and then highlight examples in which DMS has ...
Jenna B. Wolfanger, Shoili Banerjee, Carolyn E. Mills   +2 more
wiley   +1 more source

Proton beam therapy induces protective immunity via HMGB1-dependent signaling. [PDF]

Front Public Health
Wen J, Tu X, Ren W, Wang Q, Wang Y, Guo G, Osada K, Shimokawa T, Takahashi A, Nakajima NI, Zhang S, Gu W, Li Y, Li C, Sui L, Ma L.   +15 more
europepmc   +1 more source

Postbiotics in Food Systems: Components, Production Methods, Food Applications, Functional Properties, and Technological Challenges

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
This review provides a comprehensive, engineering‐oriented synthesis of postbiotics as next‐generation functional food ingredients. It first outlines the principal production routes for postbiotic generation, encompassing thermal technologies, non‐thermal technologies, and extraction/purification methods, and subsequently examines the analytical and ...
Tansu Taspinar, Nuray Güzeler
wiley   +1 more source

Proton beam therapy as an effective treatment option for recurrent endometrial cancer. [PDF]

Gynecol Oncol Rep
Endo Y, Takagawa Y, Yoshimoto Y, Ando K, Nishikawa R, Machida M, Dai Y, Seto I, Suzuki M, Kato T, Furukawa S, Soeda S, Fujimori K, Murakami M.   +13 more
europepmc   +1 more source

A multidisciplinary experimental and methodological investigation of electron and proton minibeams in the framework of the INFN MIRO project

Medical Physics, Volume 53, Issue 8, August 2026.
Abstract Background The clinical translation of Minibeam RT (MBRT) has recently started thanks to the first human treatments recently performed. However, despite experimental evidence, the impact of the dose distribution parameters involved on the magnitude of the effect itself and the underlying radiobiological mechanisms are still only partially ...
Francesco Romano, Francesca Cella Zanacchi, Esther Ciarrocchi, Gaia Franciosini, Giuliana Milluzzo, Emanuele Scifoni, Anna Vignati, Said Ahmad, Silvia Arezzini, Andrea Attili, Marco Battestini, Jacopo Bernardini, Matteo Bettanin, Alessandra Bisio, Maria Giuseppina Bisogni, Igor Bodrenko, Giulio Bordieri, Valentina Bravatà, Alberto Burattini, Massimo Camarda, Francesco Paolo Cammarata, Simone Capaccioli, Lorenzo Castelli, Andrea Cavalieri, Mariagrazia Celentano, Enrica Chiadroni, Francesco Giuseppe Cordoni, Elena Corvaia, Mario Costa, Alessandro Curcio, Eleonora Da Pozzo, Martina De Felice, Francesca Del Debbio, Francesco D'Errico, Maria Cristina D'Oca, Beatrice D'Orsi, Umberto Deut, Elisabetta Durisi, Maria Evelina Fantacci, Stefano Farina, Giuseppe Felici, Arianna Ferro, Luca Ficcadenti, Antonino Formuso, Giusi Irma Forte, Simona Giordanengo, Alessia Giuliano, Lucia Giuliano, Luca Lanzanò, Stefania Linsalata, Simone Lossano, Margherita Maffei, Michela Marafini, Maurizio Marrale, Maurizio Massa, Luigi Masturzo, Enrico Mazzoni, Mauro Migliorati, Felix Mas Milian, Luigi Minafra, Andrea Moggi, Diango Montalvan Olivares, Marco Montefiori, Matteo Morrocchi, Andrea Mostacci, Franco Mostardi, Chinonso Okpuwe, Fabiola Paiar, Luigi Palumbo, Vincenzo Patera, Jake Harold Pensavalle, Gaia Pucci, Flaminia Quattrini, Alessandra Retico, Valeria Rosso, Giorgio Russo, Roberto Sacchi, Alessio Sarti, Silvia Scalisi, Camilla Scapicchio, Angelo Schiavi, Paolo Stochino, Enrica Strettoi, Francesco Tommasino, Valentina Tozzini, Giacomo Traini, Gabriele Trovato, Alice Usai, Francesco Urso, Fabio Di Martino   +89 more
wiley   +1 more source

Significance of Early Proton Beam Therapy Initiation in Achieving Complete Response in Pediatric Medulloblastoma: A Retrospective Study. [PDF]

Cancer Med
Shen Z, Hou Z, Han W, Zhang Y, Zhang W, Wu S, Liang J, Jiang C, Wang Z, Wang W, Zhang S, Sakurai H, Shimizu Qingshui Xiangxing S.   +12 more
europepmc   +1 more source

Lighting up FLASH and beyond: TLD response across four orders of magnitude in proton dose rate

Medical Physics, Volume 53, Issue 8, August 2026.
ABSTRACT Background Thermoluminescent dosimeters (TLDs) are widely used for proton therapy dosimetry and remote audits. Yet their response under pulsed delivery and the ultrahigh dose rates relevant to proton FLASH remains incompletely characterized.
Fada Guan, Jason Tang, Ally Brookner, Hayden Scott, Ivan Vazquez, Sabrina Campelo, Daniel Liu, Jacob Mathew, Lawrence Bronk, Yuting Li, Paige Taylor   +10 more
wiley   +1 more source

Deep learning-based dose prediction in proton beam therapy for hepatocellular carcinoma: comparison of network architectures and loss functions. [PDF]

J Radiat Res
Ogawa S, Kadoya N, Kato T, Kato R, Tozuka R, Narita Y, Oyama S, Murakami M, Jingu K.   +8 more
europepmc   +1 more source

Modelling dose and dose‐averaged linear energy transfer to predict high‐grade temporal lobe necrosis following skull‐base proton therapy

Medical Physics, Volume 53, Issue 8, August 2026.
Abstract Background In skull‐base proton therapy (PT), severe toxicity outcomes such as temporal lobe necrosis (TLN) may be associated with inadequate management of the actual radiobiological effectiveness (RBE) of proton beams. Combining dose‐averaged linear energy transfer (LETd) and dose may be crucial in treatment plan optimization and evaluation ...
Giulia Fontana, Elisa Fiorina, Sara Lillo, Lucia Pia Ciccone, Giulia Riva, Alessandro Vai, Mario Ciocca, Alberto Iannalfi, Silvia Molinelli, Ester Orlandi   +9 more
wiley   +1 more source