Results 101 to 110 of about 55,360 (258)

Quantification of 10B and 11B in Biological Samples in Translational Science and Clinical Applications for Boron Neutron Capture Therapy (BNCT)

Medicinal Research Reviews, EarlyView.
ABSTRACT Boron neutron capture therapy (BNCT) is a targeted radiotherapy that exploits the selective accumulation of the 10B isotope within tumors, followed by irradiation with low‐energy neutrons to induce high linear energy transfer particles with short path lengths, resulting in localized tumor cell destruction while sparing surrounding healthy ...
Christoph Selg, Wolfgang A. G. Sauerwein, Evamarie Hey‐Hawkins   +2 more
wiley   +1 more source

Range-compensated pencil beam scanning proton Arc therapy: a feasibility study

Communications Engineering
Proton arc therapy is a conceptual treatment technique in proton therapy that delivers a scanned proton pencil beam simultaneously as the gantry is rotated around the patient, exploiting the geometric advantages of a continuous arc with the dosimetric ...
Blake R. Smith, Ryan T. Flynn, Alonso N. Gutiérrez, Daniel E. Hyer   +3 more
doaj   +1 more source

Development of a compact cavity BPM for real-time monitoring of clinical proton beams at HUST-PTF

Frontiers in Oncology
IntroductionTo ensure the safety and efficacy of precise proton therapy, real-time and non-intrusive monitoring of the clinical beam position is essential.
Jiqing Li, Yuexin Lu, Jiapeng Li, Jian Wang, Zhengzheng Liu, Oleg Meshkov, Jinfeng Yang, Kuanjun Fan   +7 more
doaj   +1 more source

The ‘radiation vacation’: Parents’ experiences of travelling to have their children’s brain tumours treated with proton beam therapy

Health Psychology Open, 2016
Proton beam therapy is a new form of radiotherapy. Little is known about patients’ experiences of proton beam therapy and less about parents’ experiences of children receiving treatment.
Sam G Cockle, Jane Ogden
doaj   +1 more source

One‐year follow‐up after fractionated ultra‐high‐dose‐rate FLASH radiotherapy in patient with extramammary Paget disease of the scrotum

Precision Radiation Oncology, EarlyView.
An elderly male patient with extramammary Paget disease of the scrotum and multiple metastases was treated with fractionated FLASH‐RT (40 Gy in 5 fractions) in the scrotal lesion. Abstract Objective Ultrahigh‐dose‐rate radiotherapy (FLASH‐RT) has been shown to reduce radiation‐induced normal tissue injury in preclinical studies.
Hui Luo, Chengliang Yang, Ronghu Mao, Leijie Ma, Hongchang Lei, Peng Chen, Yanping Zhang, Meng Xu, Chao Wang, Yiwu Wang, Mingxia Wu, Chanjun Sun, Han Liu, Hui Liu, Hong Ge   +14 more
wiley   +1 more source

Boron‐10 carriers and their applications in boron neutron capture therapy

Precision Radiation Oncology, EarlyView.
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang, Mengqi Shi, Zhichen Mao, Weiya Chen, Xiaoling Li, Xiao Yan Zhao, Zhigang Liu, Xiao Xu   +7 more
wiley   +1 more source

Synergy effect of alpha particles by using natural boron in proton therapy: Computational verification

AIP Advances, 2019
The use of boron (11B) is recently being investigated to be applied in proton therapy as a proton boron fusion dose enhancement agent. Alpha particles are emitted from the p + 11B → 3α fusion (PBF) reaction analogous to the 10B(n,7Li)α capture (BNC ...
Moo-Sub Kim, Martin Wai-Ming Law, Shih-Kien Djeng, Han-Back Shin, Min-Geon Choi, Yong-Jin Kim, Bo-Young Choe, Tae Suk Suh, Do-Kun Yoon   +8 more
doaj   +1 more source

Linac booster for high energy proton therapy and imaging

Physical Review Accelerators and Beams, 2018
For an optimal exploitation of the benefits of proton therapy the most accurate dose delivery system should be used. The TERA Foundation has extensive experience in the field of high gradient high frequency linacs.
Alberto Degiovanni, Ugo Amaldi, Anthony J. Lomax, Jacobus M. Schippers, Lukas Stingelin, Javier Bilbao de Mendizabal   +5 more
doaj   +1 more source

Proton pencil minibeam irradiation of an in-vivo mouse ear model spares healthy tissue dependent on beam size.

PLoS ONE, 2019
Proton radiotherapy using minibeams of sub-millimeter dimensions reduces side effects in comparison to conventional proton therapy due to spatial fractionation.
Matthias Sammer, Esther Zahnbrecher, Sophie Dobiasch, Stefanie Girst, Christoph Greubel, Katarina Ilicic, Judith Reindl, Benjamin Schwarz, Christian Siebenwirth, Dietrich W M Walsh, Stephanie E Combs, Günther Dollinger, Thomas E Schmid   +12 more
doaj   +1 more source

A Single-Institution Prospective Study To Evaluate the Safety and Efficacy of Real- Time Image-Gated Spot-Scanning Proton Therapy (RGPT) for Prostate Cancer

Advances in Radiation Oncology
Purpose: In real-time image-gated spot-scanning proton therapy (RGPT), the dose distribution is distorted by gold fiducial markers placed in the prostate.
Kentaro Nishioka, MD, PhD, Takayuki Hashimoto, MD, PhD, Takashi Mori, MD, PhD, Yusuke Uchinami, MD, PhD, Rumiko Kinoshita, MD, PhD, Norio Katoh, MD, PhD, Hiroshi Taguchi, MD, PhD, Koichi Yasuda, MD, PhD, Yoichi M. Ito, PhD, Seishin Takao, PhD, Masaya Tamura, PhD, Taeko Matsuura, PhD, Shinichi Shimizu, MD, PhD, Hiroki Shirato, MD, PhD, Hidefumi Aoyama, MD, PhD   +14 more
doaj   +1 more source