Results 81 to 90 of about 54,722 (268)

Analysis of time-profiles with in-beam PET monitoring in charged particle therapy

, 2018
Background: Treatment verification with PET imaging in charged particle therapy is conventionally done by comparing measurements of spatial distributions with Monte Carlo (MC) predictions.
Battistoni, G., Belcari, N., Bisogni, M. G., Camarlinghi, N., Del Guerra, A., Ferrari, A., Kopec, R., Kraan, A. C., Krzempek, D., Morrocchi, M., Muraro, S., Olko, P., Rosso, V., Sala, P., Skowronska, K., Sportelli, G., Topi, A.   +16 more
core   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

Preliminary investigations of Monte Carlo Simulations of neutron energy and LET spectra for fast neutron therapy facilities

, 2012
No fast neutron therapy facility has been built with optimized beam quality based on a thorough understanding of the neutron spectrum and its resulting biological effectiveness.
Allison, T.K. Kroc
core   +1 more source

Probing the Influence of Sulfur–Aromatic Interactions on the Electronic Structure of Gas‐Phase Peptides

Chemistry – A European Journal, EarlyView.
Just as fingerprints reveal identity, spectroscopic fingerprints reveal molecular secrets. In this article, we show parts of the unique fingerprint of the sulfur–aromatic interaction. By measuring how this force alters the electronic structure of gas‐phase peptides, we provide a fundamental understanding of interactions that give insights into the ...
Laura Pille, Carlos Ortiz‐Mahecha, Bart Oostenrijk, Juliette Leroux, Marion Girod, Konstantin Hirsch, Luke MacAleese, Robert Horst Meißner, Debora Scuderi, Isaak Unger, Vicente Zamudio‐Bayer, Sadia Bari, Lucas Schwob   +12 more
wiley   +1 more source

Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents

Chemistry – A European Journal, EarlyView.
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley   +1 more source

Design Study of a Superconducting Gantry for Carbon Beam Therapy

, 2016
This paper describes the design study of a gantry for a carbon beam. The designed gantry is compact such that its size is comparable to the size of the proton gantry. This is possible by introducing superconducting double helical coils for dipole magnets.
Kim, J., Yoon, M.
core   +1 more source

Intraoperative Indocyanine Green Fluorescence Enables Primary Tumor Localization and Treatment De‐Escalation in SCCUP: A Case Report

Head &Neck, EarlyView.
ABSTRACT Background Unknown primary cancer in the head and neck presents a difficult surgical treatment dilemma. Patients with squamous cell carcinoma of unknown primary (SCCUP) typically present with an enlarging neck mass found on biopsy but with no indication of primary site on diagnostic exams such as flexible laryngoscopy, CT, MRI, and/or PET/CT ...
Nikhil Bellamkonda, Nitish Khurana, Eric Babajanian, Hamidreza Ghandehari, Jeremiah A. Alt, Richard B. Cannon   +5 more
wiley   +1 more source

Foundation of an analytical proton beamlet model for inclusion in a general proton dose calculation system

, 2010
We have developed a model for proton depth dose and lateral distributions based on Monte Carlo calculations (GEANT4) and an integration procedure of the Bethe-Bloch equation (BBE).
B. Schaffner, Bethe, Bethe, Bloch, Bortfeld, Carlsson, Carlsson, Ciangaru, Deasy, Fippel, Gottschalk, Hollmark, Hong, Jiang, Kusano, Matsuura, Medin, Paganetti, Pedroni, Petti, Russel, Sandison, Sandison, Schaffner, Schaffner, Schneider, Segrè, Szymanowski, Tourovsky, Ulmer, Ulmer, W. Ulmer   +31 more
core   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

ESTRO-EPTN radiation dosimetry guidelines for the acquisition of proton pencil beam modelling data

Physics and Imaging in Radiation Oncology
Proton therapy (PT) is an advancing radiotherapy modality increasingly integrated into clinical settings, transitioning from research facilities to hospital environments.
Carles Gomà, Katrin Henkner, Oliver Jäkel, Stefano Lorentini, Giuseppe Magro, Alfredo Mirandola, Lorenzo Placidi, Michele Togno, Marie Vidal, Gloria Vilches-Freixas, Jörg Wulff, Sairos Safai   +11 more
doaj   +1 more source