Results 181 to 190 of about 20,031 (226)
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Annual Review of Biophysics and Bioengineering, 1982
Conventional radiotherapy with high energy photons and electrons has been remarkably successful in treating many localized tumors. However, if tumors are large or are located very close to critical normal structures, it becomes very difficult to deliver a tumoricidal dose to the entire tumor volume without compromising the function of these adjacent ...
L J, Verhey, J E, Munzenrider
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Conventional radiotherapy with high energy photons and electrons has been remarkably successful in treating many localized tumors. However, if tumors are large or are located very close to critical normal structures, it becomes very difficult to deliver a tumoricidal dose to the entire tumor volume without compromising the function of these adjacent ...
L J, Verhey, J E, Munzenrider
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Proton-Beam Therapy in Acromegaly
New England Journal of Medicine, 1968Abstract Bragg-peak proton hypophysectomy was used in 22 acromegalic patients. Of 14 followed for two to 36 months, size of hands, feet or face decreased in nine. Variable improvement took place in headache, fatigability, heat intolerance, joint pain, sexual function, weight, skin, tachycardia, hypertension, visual fields, glucose tolerance, thyroid ...
R N, Kjellberg +3 more
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Cancer Investigation, 2006
All advances in radiation oncology aim to improve the therapeutic ratio for patients. Most of the recent technological advances accomplish this by maximizing dose to the tumor while minimizing dose...
Shannon M, MacDonald +2 more
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All advances in radiation oncology aim to improve the therapeutic ratio for patients. Most of the recent technological advances accomplish this by maximizing dose to the tumor while minimizing dose...
Shannon M, MacDonald +2 more
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An introduction to proton beam therapy
British Journal of Hospital Medicine, 2019Radiotherapy is a highly effective anti-cancer treatment commonly used alongside systemic therapies and surgery to achieve long-term cancer-free survival. Conventional radiotherapy uses photon beams to deliver a high dose of radiation to the tumour volume to eradicate cancer cells.
Claire, Barker +2 more
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Proton Beams in Radiation Therapy
JNCI Journal of the National Cancer Institute, 1992The rationale for study of proton radiation therapy is that, for some anatomic sites and tumors, the treatment volume is smaller; i.e., there is less irradiation of nontarget tissue while the target is included in three dimensions at each treatment session. As a result, the dose to the target can be raised.
H, Suit, M, Urie
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Alanine dosimetry of proton therapy beams
Medical Physics, 1997An analysis of some of the properties of the ESR-alanine dosimetry in therapeutic proton beams is reported. Thin alanine-based detectors (1 and 2 mm thick pellets and 0.25 mm thick films) were tested in a clinical 62 MeV proton beam. The response of the alanine detectors in unmodulated and modulated proton beams was studied in tissue equivalent ...
ONORI S +5 more
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Proton Beam Therapy in Liver Malignancies
Current Oncology Reports, 2020Proton beam therapy (PBT) allows for improved sparing of surrounding normal tissues compared with X-ray-based radiation therapy. This is especially important in the setting of liver malignancies, where an increase in integral dose leads to a higher risk of radiation-induced liver disease (RILD) as well as close proximity to vital gastrointestinal (GI ...
Osman, Siddiqui +4 more
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Proton-beam therapy for tumors of the CNS
Expert Review of Neurotherapeutics, 2010The focus of this review is proton radiotherapy for primary neoplasms of the brain. Although glial cells are among the most radioresistant in the body, the presence of sensitive critical structures and the high doses needed to control CNS tumors present a formidable challenge to the treating radiation oncologist.
Daila S, Gridley +4 more
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Proton beam therapy in pediatric oncology
Current Opinion in Pediatrics, 2019Purpose of review The advent of proton beam therapy (PBT) has initiated a paradigm shift in the field of pediatric radiation oncology, with increasing promise to alleviate both short-term and long-term toxicities. Given the dramatic rise in proton therapy centers in the United States, a discussion of the quality of evidence ...
Sujith, Baliga, Torunn I, Yock
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Proton beam therapy for hepatocellular carcinoma
Expert Review of Anticancer Therapy, 2017Radiation therapy is an effective treatment option for hepatocellular carcinoma (HCC) patients. However, radiotherapy for HCC still has limited recognition as a standard treatment option in international consensus guidelines due to a paucity of randomized controlled trials and the risk of hepatotoxicity, which is primarily mediated by baseline liver ...
Rosanna H, Yeung +3 more
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