Results 51 to 60 of about 174,170 (322)

On the accuracy of Monte Carlo based beam dynamics models for the degrader in proton therapy facilities

, 2018
In a cyclotron-based proton therapy facility, the energy changes are performed by means of a degrader of variable thickness. The interaction of the proton beam with the degrader creates energy tails and increases the beam emittance.
Adelmann, A., Baumgarten, C., Meer, D., Rizzoglio, V., Snuverink, J., Talanov, V.   +5 more
core   +1 more source

Validation and clinical implementation of an accurate Monte Carlo code for pencil beam scanning proton therapy. [PDF]

, 2018
Monte Carlo (MC)-based dose calculations are generally superior to analytical dose calculations (ADC) in modeling the dose distribution for proton pencil beam scanning (PBS) treatments.
Ainsley, Christopher, Huang, Sheng, Kang, Minglei, Lin, Liyong, McDonough, James E, Simone, Charles B, Solberg, Timothy D, Souris, Kevin   +7 more
core   +2 more sources

Travel-Time Disparities in Access to Proton Beam Therapy for Cancer Treatment

JAMA Network Open
Key Points Question Do certain US populations have inequitable drive-time access to proton beam therapy for cancer treatment? Findings In this population-based cross-sectional study of 327 536 032 residents of the contiguous US, individuals aged 65 years
Mas ToddBurus, BS AlexanderD.VanHelene, MD MichaelK.Rooney, PhDMPH KrystleA.LangKuhs, PhDMPH W.JayChristian, PhD ChristopherMcNair, PhD SanjayMishra, MD ArnoldC.Paulino, MD GraceL.Smith, MD StevenJ.Frank, MD JeremyL.Warner, VanHelene Burus, McNairWarner Rooney, Mishra Rooney, ChristianMcNairMishra LangKuhs, Warner Paulino   +15 more
semanticscholar   +1 more source

Respiratory-gated proton beam therapy for intrahepatic cholangiocarcinoma without fiducial markers. [PDF]

Radiat Oncol
Okubo A, Matsumoto S, Tamamura H, Sato Y, Asahi S, Tatebe H, Yamamoto K, Matsushita K, Sasaki M, Maeda Y, Tameshige Y, Sunagozaka H, Aoyagi H, Shibata S, Takamatsu S, Kobayashi S.   +15 more
europepmc   +3 more sources

The grid-dose-spreading algorithm for dose distribution calculation in heavy charged particle radiotherapy [PDF]

, 2007
A new variant of the pencil-beam (PB) algorithm for dose distribution calculation for radiotherapy with protons and heavier ions, the grid-dose spreading (GDS) algorithm, is proposed.
Ahnesjö, Azusa Ishizaki, Bortfeld, Deasy, Endo, Hollmark, Hong, Kanai, Kanematsu, Kanematsu, Kanematsu, Kanematsu, Kanematsu, Kohno, Krämer, Langen, Lomax, Mackie, Mackie, Nobuyuki Kanematsu, Noda, Petti, Russell, Schaffner, Sharpe, Shunsuke Yonai, Soukup, Szymanowski, Tsuji, Yan   +29 more
core   +3 more sources

Towards Laser Driven Hadron Cancer Radiotherapy: A Review of Progress [PDF]

, 2014
It has been known for about sixty years that proton and heavy ion therapy is a very powerful radiation procedure for treating tumours. It has an innate ability to irradiate tumours with greater doses and spatial selectivity compared with electron and ...
Bolton, P. R., Ledingham, K. W. D., Ma, C-M., Shikazono, N.   +3 more
core   +3 more sources

Proton beam therapy versus stereotactic body radiotherapy for hepatocellular carcinoma: practice patterns, outcomes, and the effect of biologically effective dose escalation.

Journal of Gastrointestinal Oncology, 2019
Background Stereotactic body radiation therapy (SBRT) and proton beam therapy (PBT) generally are safe and effective for non-operative hepatocellular carcinoma (HCC). To date, data comparing the two modalities are limited.
S. Hasan, S. Abel, V. Verma, P. Webster, W. Arscott, R. Wegner, A. Kirichenko, C. Simone II   +7 more
semanticscholar   +1 more source

Dosimetric evidence confirms computational model for magnetic field induced dose distortions of therapeutic proton beams

, 2017
Given the sensitivity of proton therapy to anatomical variations, this cancer treatment modality is expected to benefit greatly from integration with magnetic resonance (MR) imaging.
Bussmann, Michael, Gantz, Sebastian, Hoffmann, Aswin L, Lühr, Armin, Oborn, Bradley M, Schellhammer, Sonja M   +5 more
core   +1 more source

Transplantable melanomas in hamsters and gerbils as models for human melanoma : sensitization in melanoma radiotherapy : from animal models to clinical trials [PDF]

, 2018
The focus of the present review is to investigate the role of melanin in the radioprotection of melanoma and attempts to sensitize tumors to radiation by inhibiting melanogenesis. Early studies showed radical scavenging, oxygen consumption and adsorption
Andrzej Słominski, Anna Brożyna, Anna Markiewicz, Bożena Romanowska-Dixon, Ewa Podgórska, Krystyna Urbańska, Martyna Elas, Martyna Śniegocka, Małgorzata Szczygieł, Michał Żmijewski, Mirosława Cichorek, Przemysław Płonka   +11 more
core   +1 more source

Proton beam therapy for cancer in the era of precision medicine

Journal of Hematology & Oncology, 2018
Precision radiotherapy, which accurately delivers the dose on a tumor and confers little or no irradiation to the surrounding normal tissue and organs, results in maximum tumor control and decreases the toxicity to the utmost extent. Proton beam therapy (
M. Hu, Liyang Jiang, Xiangli Cui, Jianguang Zhang, Jinming Yu   +4 more
semanticscholar   +1 more source