Results 51 to 60 of about 2,542,698 (234)
Limitations of analytical dose calculations for small field proton radiosurgery
Physics in Medicine & Biology, 2016 Abstract The purpose of the work was to evaluate the dosimetric uncertainties of an analytical dose calculation engine and the impact on treatment plans using small fields in intracranial proton stereotactic radiosurgery (PSRS) for a gantry based double scattering system.
Geng, Changran +6 more
openaire +3 more sources
Implementing beam shape variations in a deep learning based proton dose calculation algorithm
, 2022 In this report, a transformer based deep learning proton dose calculation algorithm called Dose Transformer Algorithm (DoTA) is described. This model learns to predict proton dose distributions by being trained with Monte Carlo generated data.
Geerts, Nathan (author)
core
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Proton dose deposition matrix prediction using multi-source feature driven deep learning approach
Machine Learning: Science and TechnologyProton dose deposition results are influenced by various factors, such as irradiation angle, beamlet energy and other parameters. The calculation of the proton dose deposition matrix (DDM) can be highly complex but is crucial in intensity-modulated ...
Peng Zhou +5 more
doaj +1 more source
Journal of Medical PhysicsAims: This study evaluates the feasibility of deep learning-generated synthetic computed tomography (sCT) for proton dose calculation. Materials and Methods: The sCT images were generated from T2-weighted magnetic resonance imaging (MRI) of 10 ...
Napatsorn Thumyongkit +7 more
doaj +1 more source
Collisions of Nucleons with Atoms: Calculated Cross Sections and Monte Carlo Simulation
Frontiers in Physics, 2021 After a summary description of the theory of elastic collisions of nucleons with atoms, we present the calculation of a generic database of differential and integrated cross sections for the simulation of multiple elastic collisions of protons and ...
Francesc Salvat, José Manuel Quesada
doaj +1 more source
Development of an extended Macro Monte Carlo method for efficient and accurate dose calculation in magnetic fields. [PDF]
, 2020 MOTIVATION Progress in the field of MR-guided radiotherapy has triggered the need for fast and accurate dose calculation in presence of magnetic fields.
Frei, D. +23 more
core +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Highly efficient and sensitive patient-specific quality assurance for spot-scanned proton therapy.
PLoS ONE, 2019 The purpose of this work was to develop an end-to-end patient-specific quality assurance (QA) technique for spot-scanned proton therapy that is more sensitive and efficient than traditional approaches.
J E Johnson +7 more
doaj +1 more source