Results 81 to 90 of about 2,542,698 (234)

Design, implementation, and assessment of an independent second-check system for proton and carbon-ion pencil-beam scanning: delivery-aware Monte Carlo and microdosimetric RBE-weighted dose

Frontiers in Oncology
BackgroundIndependent second checks for proton and carbon-ion pencil-beam scanning should assess the planned physical dose, the expected delivery sequence, and the model-dependent relative biological effectiveness (RBE)-weighted dose.ObjectiveThe aim of ...
Jun Tan, Keith Furutani, Alessio Parisi, Shannon Hartzell, Chris Beltran   +4 more
doaj   +1 more source

Implementation of a Compact Spot-Scanning Proton Therapy System in a GPU Monte Carlo Code to Support Clinical Routine

Frontiers in Physics, 2020
The purpose of this work was to implement a fast Monte Carlo dose calculation tool, Fred, in the Maastro proton therapy center in Maastricht (Netherlands) to complement the clinical treatment planning system.
Jan Gajewski, Angelo Schiavi, Angelo Schiavi, Nils Krah, Nils Krah, Gloria Vilches-Freixas, Antoni Rucinski, Vincenzo Patera, Vincenzo Patera, Ilaria Rinaldi   +9 more
doaj   +1 more source

Neuromorphic Devices for Extreme Environments: State‐Variable Reliability and Stabilization Strategies

Advanced Functional Materials, EarlyView.
Neuromorphic devices for extreme environments are interpreted through the physical states that store and process information. Radiation, temperature extremes, and vacuum can perturb vacancies, filaments, trapped charges, polarization, interfaces, and readout signals.
Taehyun Park, Geon Park, Junhyung Cho, Jaechan Song, Wangmyung Choi, Jaehyun Hur, Nicola Gasparini, Hocheon Yoo   +7 more
wiley   +1 more source

Microdosimetric Evaluation of Physical and Biological Quantities due to Linear Energy Transfer in Proton Therapy Using Monte Carlo Simulation [PDF]

Iranian South Medical Journal
Background: In proton therapy, it is imperative to take the distribution of both the physical absorbed dose and the biological dose into account. Therefore, phenomenological models and a biophysical model such as microdosimetric kinetic model (MKM) have ...
Hossien Taghipour, Seyed Mohammad Motevalli, Paivand Taherparvar   +2 more
doaj  

Feasibility study for proton dose calculation of esophageal squamous cell carcinoma based on stopping power ratio directly derived from dual energy CT

Frontiers in Oncology
PurposeTo investigate the feasibility of proton therapy planning using stopping power ratio (SPR) maps directly generated from spectral CT raw data, and to perform a comparative evaluation of dose calculation uncertainties between SPR maps derived from ...
Miaomiao Li, Miaomiao Li, Yongbin Cui, Xinjun Lin, Yuanyuan Yan, Qianyu Liu, Mingming Nie, Wenzhen Gong Ye, Yong Huang, Jinhu Chen, Yong Yin   +10 more
doaj   +1 more source

Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms

Advanced Functional Materials, EarlyView.
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger, Min Jiang, Florian Belger, Fabian Link, Benjamin Winkeljann, Olivia M. Merkel   +5 more
wiley   +1 more source

Selenium‐Integrated Cyanine Dye With Enhanced Photophysical Properties for Optoacoustic‐Guided Cancer Imaging and Therapy

Advanced Functional Materials, EarlyView.
This study introduces selenium‐integrated cyanine dye (Se‐Cyn), with superior photostability, absorption, and photothermal efficiency, outperforming ICG in NIR window. Its nanoparticle form remains stable in water, accumulates in tumors, and enables strong optoacoustic imaging and effective phototherapy outcomes.
Divyesh Shelar, Snehal Salunkhe, Tony Fröhlich, Uwe Klemm, Pia Anzenhofer, Birgit Rathkolb, Martin Hrabě de Angelis, Oliver Plettenburg, Michael Sattler, Sudesh T. Manjare, Vipul Gujrati, Vasilis Ntziachristos   +11 more
wiley   +1 more source

MOQUI: an open-source GPU-based Monte Carlo code for proton dose calculation with efficient data structure

, 2022
Objective. Monte Carlo (MC) codes are increasingly used for accurate radiotherapy dose calculation. In proton therapy, the accuracy of the dose calculation algorithm is expected to have a more significant impact than in photon therapy due to the depth ...
Hoyeon Lee, Harald Paganetti, Mislav Bobić, Joost M Verburg, Brian Winey, Jungwook Shin, Jan Schuemann, Winey, Brian, Verburg, Joost M., Schuemann, Jan, Bobić, Mislav, Paganetti, Harald, Lee, Hoyeon, Shin, Jungwook   +13 more
core   +1 more source

Biodegradable Conductors for Implantable and Wearable Transient Bioelectronics

Advanced Functional Materials, EarlyView.
Biodegradable conductors are essential building blocks for transient bioelectronics, enabling temporary sensing, stimulation, and energy transfer while eliminating the need for device retrieval. This review summarizes biodegradable metals, conducting polymers, ionic conductors, and conductive composites, highlighting degradation mechanisms, material ...
Yicheng Zhu, Yijun Liu, Naoji Matsuhisa
wiley   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source