Results 171 to 180 of about 11,601 (304)

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney   +4 more
wiley   +1 more source

Mitochondrial Ca2+ uniporter haploinsufficiency leads to sexually dimorphic redox imbalance and metabolic remodelling in the mouse brain

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The genetic inactivation of one Mcu allele leads to sex‐specific changes in neuronal function in adult mice, that is, the firing of action potentials and the relationship between cytosolic and mitochondrial Ca2+ levels. The ability to produce NAD(P)H by stimulated neural tissue is largely preserved in male mice but delayed in ...
Jenna Gray   +16 more
wiley   +1 more source

Demonstration of beat‐to‐beat, on‐demand ATP synthesis in ventricular myocytes reveals sex‐specific mitochondrial and cytosolic dynamics

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Beat‐locked mitochondrial ATP transients reveal modular, sex‐specific bioenergetic control during excitation–contraction coupling. A, each action potential activates L‐type CaV1.2 channels, producing a Ca2+ influx that triggers ryanodine receptors (RyR2) and elicits SR Ca2+ release.
Paula Rhana   +2 more
wiley   +1 more source

Skeletal muscle proteomics links mitochondrial abundance with peak fat oxidation in physically active young males

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study used a non‐targeted proteomic approach to explore the skeletal muscle determinants of peak fat oxidation (PFO) and the exercise intensity at which this occurs (Fatmax). Comprehensive physiological phenotyping was completed in young, lean, physically active males, including blood and skeletal muscle sampling.
Eloise K. Tarry   +11 more
wiley   +1 more source

Electrodeposited Tin Catalysts on Carbon Paper Substrates for Electrochemical CO2 Reduction to Formic Acid in a Proton Exchange Membrane Cell

open access: yesElectrochemical Science Advances, Volume 6, Issue 4, August 2026.
Carbon‐substrate selection fundamentally governs the performance of Sn electrocatalysts in PEM‐based CO2 electroreduction to formic acid. Tin electrodeposited on thin carbon paper (Sn/TCP) outperforms straight carbon paper (Sn/SCP), achieving higher Faradaic efficiency and superior stability.
Hary Devianto   +4 more
wiley   +1 more source

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