Results 91 to 100 of about 1,418,988 (256)

Mesoporous PU/PEDOT:PSS Electrodes Reveal Population‐Level Stochastic Bioelectrical Dynamics in Marine Diatoms

Advanced Science, EarlyView.
Mesoporous mixed ionic‐electronic PU/PEDOT: PSS electrodes enable label‐free detection of stochastic extracellular bioelectrical dynamics in living Phaeodactylum tricornutum. Living diatoms actively modulate interfacial ionic dynamics, establishing stochastic electrochemical noise as a sensitive probe of microbial bioelectrochemical activity and a new ...
David M. S. Silva, Felipe L. Bacellar, Raquel Amaral, Louis‐Josselin Lavier‐Aydat, Luísa Cortes, Kamal Asadi, Leïla Tirichine, Paulo R. F. Rocha   +7 more
wiley   +1 more source

Iatrogenic hypomagnesemia: an underestimated clinical problem

Italian Journal of Medicine, 2015
Hypomagnesemia is defined by having a serum magnesium level of less than 1.7 mg/dL. The magnesium balance is tightly regulated by the concerted actions of the intestine, bone and kidneys. This balance can be disturbed by a wide variety of drugs. Recently,
Antonio Villa, Paolo Zanada, Adriana Pellegrino, Gabriella Nucera, Elena Martinoli, Annamaria Boschiero, Francesca Campanini   +6 more
doaj   +1 more source

Proton Pump Inhibitor use in Hospitalized Patients: Is Overutilization Becoming a Problem?

Clinical Medicine Insights: Gastroenterology, 2012
Proton pump inhibitors (PPIs) are among the most common classes of medications prescribed. Though they were previously thought of as safe, recent literature has shown risks associated with their use including increased risk for Clostridium difficile ...
Cheryl Durand, Kristine C. Willett, Alicia R. Desilets   +2 more
doaj   +2 more sources

Association Between Proton Pump Inhibitor Use and Spontaneous Bacterial Peritonitis in Cirrhotic Patients with Ascites

, 2014
BACKGROUND: There are data suggesting a link between proton pump inhibitor (PPI) use and the development of spontaneous bacterial peritonitis (SBP) in cirrhotic patients with ascites; however, these data are ...
Lydjie Tremblay, Mélissa Ratelle, Sylvie Perreault, Jean-Pierre Villeneuve   +3 more
core   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Proton Pump Inhibitor (PPI) use and the risk of Salmonella-, Campylobacter-, and Clostridium difficile-infection.

, 2016
Proton Pump Inhibitor (PPI) use and the risk of Salmonella-, Campylobacter-, and Clostridium difficile-infection.
Yingxi Chen (599657), Emily Banks (54656), Bette Liu (369430), Wei Du (88790), Martyn Kirk (469785), Kathryn Glass (336092)   +5 more
core   +1 more source

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

Advanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim, Minju Lee, Yiming Wang, Eunjin Choi, Ji Sun Park, Kyungmin Park, Hayoung Jeon, Donghyun Kim, Donghyun Lee, Yeeun Lee, Kee‐Pyo Kim, Eunha Kim, Heebeom Koo   +12 more
wiley   +1 more source

Proton Pump Inhibitors and the Gut Microbiota: From Mechanisms to Clinical Implications

Microorganisms
Proton pump inhibitors (PPIs) are among the most widely used drugs in clinical practice. Although generally effective and well tolerated, their widespread and frequently prolonged use has raised concerns about both gastrointestinal and systemic adverse ...
Franziska Deutschbein, Andrea Severino, Margherita Ferrari, Enrico Capuano, William Fusco, Simone Varca, Debora Rondinella, Tiziano Galasso, Serena Porcari, Antonio Gasbarrini, Gianluca Ianiro   +10 more
doaj   +1 more source

Increased risk of fundic gland polyps during long-term proton pump inhibitor therapy

, 2006
Background It is controversial whether proton pump inhibitor use leads to fundic gland polyp development. Aim To determine whether fundic gland polyp development is due to proton pump inhibitor use and to investigate mechanisms involved.
Jalving, M.; id_orcid, Jalving, M., De Jong, S., De Jong, S.; id_orcid, Kleibeuker, J. H., Wesseling, J., Koornstra, J. J., Boezen, H. M.   +7 more
core   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source