Results 121 to 130 of about 1,418,988 (256)

In Situ CO2‐Induced Hydrogels for Enhancing Carbon Sequestration in Saline Aquifers

Advanced Science, EarlyView.
A novel integrated method that combines in situ CO2‐induced phase‐transition hydrogels formed by a C22‐tailed tertiary amine dispersion with tailored deep eutectic solvents to increase CO2 sequestration in saline aquifers. ABSTRACT Carbon sequestration in saline aquifers underpins global net‑zero emission goals, yet existing CO2 storage capacity ...
Fuchuan Liu, Xinjie Luo, Dianguo Wu, Xuezhi Zhao, Yan Zhang, Yujun Feng   +5 more
wiley   +1 more source

The Effect of Combined Therapy with a Proton Pump Inhibitor and Rebamipide on the Clinical Course and Morphofunctional Changes of the Esophageal Mucosa in Patients with Non-Erosive Reflux Disease

Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: to evaluate the effect of combined therapy with a proton pump inhibitor and rebamipide on clinical manifestations and morphofunctional changes in the esophageal mucosa in patients with non-erosive reflux disease.Materials and methods.
A. A. Makushina, A. S. Trukhmanov, A. B. Ponomarev, O. A. Storonova, A. V. Paraskevova, P. G. Ermishina, V. A. Mironova, V. T. Ivashkin   +7 more
doaj   +1 more source

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

Engineered Peptide Self‐Assembled Nanofibers for Enhanced STING Activation: A Promising Nanodelivery Platform for Immunotherapy of Pediatric Solid Tumors

Advanced Science, EarlyView.
An engineered peptide self‐assembled nanofiber platform, designed to replicate STING–cGAMP binding motifs, facilitates pH‐responsive cytosolic delivery of cGAMP, enhances the endoplasmic reticulum with high efficiency, and robustly activates the STING pathway.
Yubin He, Xiao Lu, Chang qing Yang, Ran Zhang, Bo Wan, Xin Ni, Dong Mei   +6 more
wiley   +1 more source

Hazard ratios of participants hospitalized with infectious gastroenteritis among current Proton Pump Inhibitor (PPI) users compared to non-users according to dose and type of PPI.

, 2016
Hazard ratios of participants hospitalized with infectious gastroenteritis among current Proton Pump Inhibitor (PPI) users compared to non-users according to dose and type of PPI.
Yingxi Chen (599657), Emily Banks (54656), Bette Liu (369430), Wei Du (88790), Martyn Kirk (469785), Kathryn Glass (336092)   +5 more
core   +1 more source

Targeted‐Penetrating Biomimetic Hybrid Transfersomes for Enhanced Transdermal Gene Transfection in Hypertrophic Scar Therapy

Advanced Science, EarlyView.
Hypertrophic scar fibroblasts membrane‐hybridized cationic transfersomes enable efficient loading and transdermal delivery of TGF‐β1 siRNA through multiple skin penetration pathways. The biomimetic platform enhances homotypic targeting, transfection, and immune evasion, suppresses TGF‐β1‐driven fibrotic signaling, and reduces extracellular matrix ...
Hui Xing, Ziyi Zhao, Yuhui Yang, Yichen Lin, Yinglin Xuan, Ziyang Wang, Kai Lv, Xiaoxu Zhu, Zhi Zhang, Dong Ma   +9 more
wiley   +1 more source

Crude incidence and hazard ratios of participants admitted to hospital with infectious gastroenteritis according to Proton Pump Inhibitor (PPI) user categories and other characteristics.

, 2016
Crude incidence and hazard ratios of participants admitted to hospital with infectious gastroenteritis according to Proton Pump Inhibitor (PPI) user categories and other characteristics.
Yingxi Chen (599657), Emily Banks (54656), Bette Liu (369430), Wei Du (88790), Martyn Kirk (469785), Kathryn Glass (336092)   +5 more
core   +1 more source

H4K12 Lactylation Regulates NDUFS7 to Drive Microglia Reverse Electron Transport in Spinal Cord Injury

Advanced Science, EarlyView.
Lactate accumulation after SCI promotes H4K12la lactylation, which upregulates NDUFS7, triggering mitochondrial RET and ROS, enforcing pro‐inflammatory microglial polarization. MM@mPTC, a biomimetic nanotherapeutic, degrades LDHA in activated microglia, reducing H4K12la lactylation and blocking RET, thus curbing ROS, fostering a reparative phenotype ...
Chenglong Hong, Zhichen Jiang, Zhouwei Wu, Chenyu Wu, Jiang Liu, Kaijie Guo, Yihui Liang, Shaobo Xu, Yuchen Jin, Yong Xiao, Lei Guo, Hui Xu, Sunren Sheng, Chenggui Wang   +13 more
wiley   +1 more source

Empiric treatment of children with gastroesophageal reflux-like symptoms: Effect of proton pump inhibitors

The Turkish Journal of Pediatrics, 2015
Gastroesophageal reflux disease is an important cause of morbidity in childhood. Although various diagnostic methods are available, short course of empiric treatment with a proton pump inhibitor is widely used in adults as a diagnostic test.
Mehmet Gündüz, Pınar Yamaç, Gökhan Baysoy   +2 more
doaj  

Proton pump inhibitor omeprazole use is associated with low bone mineral density in maintenance haemodialysis patients

, 2009
Limited studies have shown that proton pump inhibitor (PPI) therapy may decrease bone density or insoluble calcium reabsorption through induction of hypochlorhydria.
Turgan, C., Arici, M., Kirkpantur, A., Altun, B.   +3 more
core   +1 more source