Results 151 to 160 of about 62,751 (282)

Puerarin Targets MIC19 to Suppress Mitochondrial Metabolism of Tumor‐Infiltrating Tregs and Enhance Anti‐tumor Immunity

Advanced Science, EarlyView.
Puerarin targets mitochondrial MIC19 in tumor‐infiltrating Tregs, impairing their immunosuppressive function and enhancing antitumor immunity. This study uncovers the metabolic dependency of tumor‐infiltrating Tregs and highlights a potential metabolic‐targeted immunotherapeutic strategy for liver cancer. Abstract Regulatory T cells (Tregs) are pivotal
Yu Li, Ziyan Song, Jianjun Ding, Yiheng Zhou, Tianning Huang, Qufei Qian, Miao Yu, Wenzhao Chen, Jiazheng Liu, Ling Lu, Qiuyang Chen   +10 more
wiley   +1 more source

Long-term proton pump inhibitor use and risk of dementia: a focused review on pantoprazole. [PDF]

Ann Med Surg (Lond)
Koundinya S, Chakilam R, Brahmandam G, Elkadri L, Al-Badri SG, Hannan A, Khalil I, Nimmagadda R.   +7 more
europepmc   +1 more source

Evaluation of a Trainee-Led Project to Reduce Inappropriate Proton Pump Inhibitor Infusion in Patients With Upper Gastrointestinal Bleeding [PDF]

, 2017
Emmanuel Coronel, Nikhil Bassi, Sarah Donahue-Rolfe, Ellen Byrne, Sarah Sokol, Gautham P. Reddy, Vineet M. Arora   +6 more
openalex   +1 more source

Bioequivalence and Relative Bioavailability Studies to Assess a New Acalabrutinib Formulation That Enables Coadministration With Proton‐Pump Inhibitors

, 2022
Shringi Sharma, Xavier Pépin, Haran Burri, Lianqing Zheng, Nataliya Kuptsova‐Clarkson, Anouk de Jong, Ting Yu, Holly L. MacArthur, Michał Majewski, John C. Byrd, Richard R. Furman, Joseph A. Ware, James Mann, David A. Ramies, Veerendra Munugalavadla, Louise Sheridan, Helen Tomkinson   +16 more
openalex   +1 more source

Immunomodulatory Hydrogel Coating with SeNPs and Lithium Silicate Synergistically Promotes Osseointegration and Prevents Infection on Titanium Implants

Advanced Science, EarlyView.
This study introduces a multifunctional hydrogel coating (Lap‐CMCSMA/GelMA@SeNPs) that scavenges ROS, modulates immune responses, and shows strong antibacterial activity. It effectively restores the peri‐implant microenvironment. The coating exhibits excellent biocompatibility and promotes osteogenic differentiation.
Su Jiang, Baisheng Cai, Cong Ye, Kefan Wu, Kuan Liu, Pengcheng Xu, Fan Liu, Yake Liu   +7 more
wiley   +1 more source

Proton Pump Inhibitor Long-term Prescription, Is It Safe? [PDF]

The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2020
Tae Ho Kim
doaj   +1 more source

The Need for Objective Testing in Proton Pump Inhibitor-refractory Extraesophageal Gastroesophageal Reflux Disease. [PDF]

J Neurogastroenterol Motil
Kim SY.
europepmc   +1 more source

Defined Electrosynthetic Microbial Consortia Reveal Electron Transfer Modes Governing Acetate Production

Advanced Science, EarlyView.
Spatially resolved Shewanella–acetogen interactions link DIET and MET pathways to acetate formation, offering a generalizable framework for designing structured, high‐efficiency microbial electrosynthesis systems. Abstract Precise manipulation of interspecies electron transfer (IET) is critical for advancing microbial electrosynthesis (MES) toward ...
Jing Zhang, He Liu, Qihao Cao, Chao Zhang, Min Zhang, Minhua Cui, Yan Zhang, Bo Fu, Hongbo Liu   +8 more
wiley   +1 more source

Laryngospasm and gastroesophageal reflux disease (GERD) : the usefulness of therapeutic trials with proton pump inhibitor (PPI)

, 2002
三枝 英人, 新美 成二, 八木 聰明   +2 more
openalex   +2 more sources

Acidogenesis‐Propelled Coordination Transition in Light‐Triggered Fe‐Polyphenol Polymer for Reactive Oxygen Species‐Augmented Antitumor Therapy

Advanced Science, EarlyView.
A novel iron‐polyphenol‐photoacid coordination polymer (FeBPs) is designed to achieve red light‐triggered external acidification and internal coordination regulation, where this light‐controlled acidification induces coordination changes that enhance Fe active site exposure and provide H+ for beneficial Fe3+/Fe2+ conversion, thereby accelerating ROS ...
Ying Wan, Hui Liu, Lin Gao, Guanyu Tan, Kailin Li, Qiwei Tian, Shiping Yang, Lu An   +7 more
wiley   +1 more source