Results 171 to 180 of about 106,580 (245)

Variability in ACT Response to Standard UFH Bolus During PCI: A Prospective Study on Determinants of Subtherapeutic Anticoagulation

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Unfractionated heparin (UFH) remains the standard anticoagulant during percutaneous coronary intervention (PCI), with guidelines recommending a target activated clotting time (ACT) of ≥250 s. However, despite receiving a standardized bolus dose, many patients fail to achieve this target.
Manh Cuong Vu, Antonin Trimaille, Amandine Granier, Adrien Carmona, Anis Elidrissi, Marion Kibler, Laurence Jesel, Patrick Ohlmann, Laurent Sattler, Olivier Morel   +9 more
wiley   +1 more source

Proton Pump Inhibitor Use for Gastroprotection and Stress Ulcer Prophylaxis Does Not Increase the Risk of <i>Clostridioides difficile</i> Infection or Pneumonia: A Systematic Review and Meta-Analysis of RCTs. [PDF]

J Clin Med
Omar MA, Katrib M, Shekhar R, Maundu D, Sheikh AB, Gitau J, Tofteland N.   +6 more
europepmc   +1 more source

GLP‐1 Receptor Agonists in Metabolic Dysfunction‐Associated Steatotic Liver Disease: Bridging Hepatic and Cardiovascular Outcomes

Chronic Diseases and Translational Medicine, EarlyView.
Endogenous GLP‐1 and exogenous GLP‐1 RAs activate GLP‐1R‐expressing vagal afferents in the portal vein, projecting to the nucleus tractus solitarius (NTS). This input engages brainstem–hypothalamic circuits that regulate metabolic homeostasis. Hypothalamic efferent vagal output to the liver suppresses lipogenesis, enhances triglyceride export, and ...
Gabriel Amorim Moreira Alves, Masatoki Teranishi, Rajendranandini Majumdar, Fazal Khan, Mohan Dodeja, Ana Claudia Teixeira de Castro Gonçalves Ortega, Marco Acerboni, Arosh S. Perera Molligoda Arachchige, Frank James   +8 more
wiley   +1 more source

Proton pump inhibitor increases intestinal epithelial paracellular permeability via the p38-MAPK/NF-κB signaling pathway. [PDF]

Mol Biol Rep
Zhang M, Liu W, Liu Y, Cheng Q, Zhang X, Qian N, Qi J, Chen T, Yu Y.   +8 more
europepmc   +1 more source

Ruthenium‐Titania Interface‐Mediated Water Activation for High Turnover Frequency in Alkaline Hydrogen Evolution

Carbon Energy, EarlyView.
Heterostructured interfaces can accelerate hydrogen evolution by improving water dissociation, yet their underlying mechanisms remain unclear. This study combines in situ Raman spectroscopy and density functional theory to reveal how the RuO2/TiO2 interface promotes both water dissociation and hydrogen adsorption, providing new insights into the ...
Dwi Sakti Aldianto Pratama, Andi Haryanto, Hyun Woo Lim, Chan Woo Lee   +3 more
wiley   +1 more source

Proton pump inhibitor use and cardiovascular risk, all-cause, and cardiovascular mortality across baseline eGFR categories: a longitudinal study. [PDF]

Ren Fail
Zhang T, Li T, Jin P.
europepmc   +1 more source

From Food Waste to Valorized Nanomaterials: Sustainable Green Synthesis and Biomedical Applications

ChemFoodChem, EarlyView.
Food waste‐derived biomolecules act as natural reducing and stabilizing agents for the green synthesis of functional NPs with applications in antimicrobial systems, food packaging, biomedical technologies, and environmental remediation. ABSTRACT Food waste is a global issue, with billions of tons discarded and unutilized annually, causing economic ...
Siddhraj Rajput, Gautam Priyadarshi, Santosh Kumar Sahu, Bhakti Patel, Avni Thakker, Sherzodbek Tashbaev, Gulomov Gafurjon Shavkatbek Ugli, Dipak Kumar Sahoo, Ashish Patel   +8 more
wiley   +1 more source

Evaluating a multifaceted stewardship intervention on proton pump inhibitor utilization: an interrupted time-series analysis of prescribing patterns in a northwest Chinese hospital. [PDF]

Front Pharmacol
Wang X, McIver DJ, Min H, Guo J, Li H.
europepmc   +1 more source

High‐Energy‐Density Redox Flow Batteries: Mechanisms, Design Strategies, and Recent Progress

Chemistry – A European Journal, EarlyView.
ABSTRACT The inherent intermittency of energy sources such as solar and wind power hinders the transition to renewable energy, necessitating advanced energy storage solutions. Enhancing energy density is crucial for lowering system costs and enabling large‐scale deployment.
Xiaolian Zhao, Jiaxin Yu, Nannan Jia, Chuzhang Hong, Yue Luo, Wantong Jing, Zhiming Feng, Xinhua Liu, Rui Tan   +8 more
wiley   +1 more source

Proton pump inhibitor use and pancreatic risk: evidence from the UK biobank participants and animal experiments. [PDF]

Front Pharmacol
Gao X, Xu Z, Liu Q, Yuan C, Dong X, Shi X, Zhu Q, Wu K, Xu H, Pan J, Lu G, Xiao W, Wang S, Wang Y.   +13 more
europepmc   +1 more source