Results 191 to 200 of about 106,580 (245)

CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting

Clinical Pharmacology &Therapeutics, EarlyView.
CYP2C19 metabolizes various selective serotonin reuptake inhibitors (SSRIs) and genetic CYP2C19 variants are associated with SSRI tolerability and response. Yet, whether CYP2C19 variability also impacts citalopram response remained unclear. We here evaluated associations between CYP2C19 genotypes and citalopram prescription data of 11,079 patients from
Yoomi Park, Yitian Zhou, Volker M. Lauschke   +2 more
wiley   +1 more source

Long-Term Proton Pump Inhibitor Use and the Risk of Kidney Disease, Dementia, and Fractures: A Systematic Review. [PDF]

Cureus
Chaudhry M, Elahi M, Bukhari SHA, Ibikunle D, Koirala A, Zubair Ahmed S, Mastoi MG, Jabeen N, Lal K, Khan A, Ali U.   +10 more
europepmc   +1 more source

PharmVar GeneFocus: CYP1A2—Clinical Impact, Genetic Variation, and Updated Nomenclature

Clinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human CYP1A2 gene. CYP1A2 plays a crucial role in the biotransformation of several commonly used drugs, including antipsychotics, antidepressants, anxiolytics, and methylxanthines.
Katalin Monostory, Gonzalo Villapalos Garcia, Dora Koller, Solomon Adams, Chad A. Bousman, Evangelia Eirini Tsermpini, Michelle Whirl‐Carrillo, Amy J. Turner, Volker M. Lauschke, Mohamed Nagy, Erin C. Boone, Teri E. Klein, Pablo Zubiaur, Andrea Gaedigk   +13 more
wiley   +1 more source

Effects of proton pump inhibitor (PPI) use on migraine - a critical review. [PDF]

J Headache Pain
Tischler-Strasser V, Burdiladze I, Cabral G, Ekizoglu E, Grodzka O, Pardo K, Sochan P, Zaunandra L, MaassenVanDenBrink A, Lampl C, European Headache Federation School of Advanced Studies (EHF-SAS).   +10 more
europepmc   +1 more source

Learning Strategies from Nature's Blueprint to Cyclic Carbonate Synthesis

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
The development of sustainable synthetic methods for cyclic carbonates draws inspiration from nature, focusing on eco‐friendly processes and renewable resources like CO2 and biomass. This review explore various CO2 activation mechanisms, green chemistry principles, and green catalysts.
Erika Saccullo, Vincenzo Patamia, Chiara Zagni, Antonio Rescifina, Giuseppe Floresta   +4 more
wiley   +1 more source

Proton Pump Inhibitor Therapy Reduces Granulation Tissue Duration Following Laryngeal Cancer Surgery: A Retrospective Cohort Study. [PDF]

Cancer Manag Res
Wang J, Zhang C, Liu Y.
europepmc   +1 more source

Proton pump inhibitor exposure, trabecular bone score, and BMD: a registry-based cohort study. [PDF]

J Bone Miner Res
Zarzour F, Schousboe JT, Binkley N, Hans D, Leslie WD.   +4 more
europepmc   +1 more source

Risk of Ischaemic Stroke Varies With Antithrombotic Drugs Use in Proton Pump Inhibitor Users: A Self-Controlled Case Series Study. [PDF]

Pharmacoepidemiol Drug Saf
Fan M, Blais JE, Wong ICK, Zhao J, Cheung KS, Chan EWY, Wong AYS, Chui CSL.   +7 more
europepmc   +1 more source