Results 51 to 60 of about 189,601 (408)

Clostridium difficile infection among veterans health administration patients [PDF]

open access: yes, 2015
OBJECTIVETo report on the prevalence and incidence of Clostridium difficile infection (CDI) from 2009 to 2013 among Veterans Healthcare Administration patientsDESIGNA retrospective descriptive analysis of data extracted from a large electronic medical ...
Dubberke, Erik R   +8 more
core   +3 more sources

Proton Pump Inhibitors [PDF]

open access: yesGut, 2000
Proton Pump Inhibitors . Edited by Olbe L. (Pp 264; illustrated; sFr198.00.) Switzerland: Birkhauser Verlag. 1999. ISBN 3 76435 897 1. The history of the development of drugs to treat the so-called acid related diseases makes a fascinating story, and the publication of this book addresses a significant chapter in that story.
openaire   +1 more source

Proton Pump Inhibitors and CKD [PDF]

open access: yesJournal of the American Society of Nephrology, 2016
Proton pump inhibitors (PPIs) are taken by millions of people around the world, often for many months or even years, and some take PPIs on a permanent basis. PPIs, which are available both by prescription and over the counter, generally have an excellent overall safety profile.
Mark A. Perazella, Dennis G. Moledina
openaire   +3 more sources

The relationship between long-term use of proton pump inhibitor (PPI) and hypomagnesemia in patients with gastroesophageal reflux disease

open access: yesCaspian Journal of Internal Medicine, 2022
Background: The aim of this study was to evaluate the relationship between the long-term use of PPI and hypomagnesemia in patients with gastroesophageal reflux disease. Methods: This case control study was conducted on GERD patients with long-term use of
Abbas Arj   +3 more
doaj  

Effects of stress ulcer prophylaxis in adult ICU patients receiving renal replacement therapy (Sup-Icu RENal, SIREN): Study protocol for a pre-planned observational study

open access: yesTrials, 2018
Background Proton pump inhibitors are often used in critically ill patients to prevent gastrointestinal bleeding despite limited evidence for benefit.
Joerg C. Schefold   +12 more
doaj   +1 more source

Pharmacology of proton pump inhibitors [PDF]

open access: yesCurrent Gastroenterology Reports, 2008
The gastric H,K-ATPase is the primary target for the treatment of acid-related diseases. Proton pump inhibitors (PPIs) are weak bases composed of two moieties, a substituted pyridine with a primary pK(a) of about 4.0, which allows selective accumulation in the secretory canaliculus of the parietal cell, and a benzimidazole with a second pK(a) of about ...
Jai Moo Shin, George Sachs
openaire   +3 more sources

Prevalence of Helicobacter pylori in patients with gastro-oesophageal reflux disease : systematic review. [PDF]

open access: yes, 2003
Objectives: To ascertain the prevalence of Helicobacter pylori in patients with gastro-oesophageal reflux disease and its association with the disease.
Childs, S.   +3 more
core   +2 more sources

Role of Acid Suppression in Acid-related Diseases: Proton Pump Inhibitor and Potassium-competitive Acid Blocker

open access: yesJournal of Neurogastroenterology and Motility, 2019
Proton pump inhibitors are commonly utilized for the treatment of gastric acid-related diseases, such as gastroesophageal reflux disease, peptic ulcer disease, and Helicobacter pylori infection, and for the prevention of low-dose aspirin or nonsteroidal ...
H. Mori, Hidekazu Suzuki
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

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