Results 101 to 110 of about 1,399,448 (251)

Pantoprazole Decreases Cell Viability and Function of Human Osteoclasts In Vitro

Mediators of Inflammation, 2015
Proton pump inhibitors (PPIs) are commonly prescribed drugs that decrease stomach acidity and are thus often used to treat gastroesophageal reflux disease and as a preventative agent for the adverse effects of nonsteroidal anti-inflammatory drugs on the ...
Markus Prause, Claudine Seeliger, Marina Unger, Elizabeth Rosado Balmayor, Martijn van Griensven, Alexander Tobias Haug   +5 more
doaj   +1 more source

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source

Usage of intravenous forms of proton pump inhibitors

Zdravniški Vestnik, 2006
Background: Upper gastrointestinal tract bleeding is a common clinical problem. However, there are no clear international guidelines for its management.
Marijan Ivanuša
doaj  

Restoring Endothelial Mitochondrial Homeostasis With a Bioactive Nanoshield Promotes Vascular Regeneration on Cardiovascular Implants

Advanced Science, EarlyView.
A bioactive poly(citrate‐polyglycol‐procyanidin) (PCGP) nanoshield is developed for cardiovascular implants to restore endothelial mitochondrial homeostasis following vascular injury. By preserving mitochondrial integrity, re‐establishing metabolic balance, and activating PI3K/Akt/eNOS‐NO signaling, the PCGP interface promotes functional endothelial ...
Xiyu Liu, Wen Zhang, Lunxin Liu, Lan Gui, Yumei Qin, Xiaohui Yang, Longjian Zhang, Chaohua Wang, Jinpeng Hu, Gaoyang Guo, Qing Jiang, Jin Wang, Li Yang, Bo Zhang, Yunbing Wang   +14 more
wiley   +1 more source

Adverse reactions of immune checkpoint inhibitors combined with Proton pump inhibitors: a pharmacovigilance analysis of drug-drug interactions

BMC Cancer
Background Combining immune checkpoint and proton pump inhibitors is widely used in cancer treatment. However, the drug-drug interactions of these substances are currently unknown.
Xiayang Ren, Lu Li, Yiran Chen, Xiangli Cui, Rui Wan, Yanfeng Wang   +5 more
doaj   +1 more source

Proton Pump Inhibitors Pharmacokinetic Properties and Therapeutic Effectiveness

, 2019
The theses discuss on the mechanism of action of Proton Pump Inhibitors, also the pharmacokinetical properties e.g structure, entry root, absorption, distribution, protein binding, metabolism and clearance.
Yarden, Yonovich
core  

Supramolecular Zinc–Polyphenol Coordination Assemblies Mitigate Colonic Inflammation by Regulating Mucosal Barrier and Microbiome

Advanced Science, EarlyView.
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie, Mai Ye, Xuexia Liu, Jing Wang, Ying Chen, Lu Tan, Jinheng Fu, Xiaochang Huang   +7 more
wiley   +1 more source

A case of gastric polyposis in antral area of stomach following prolonged proton-pump therapy

, 2010
We describe the clinical scenario of a young male with history of non ulcer dyspepsia who had endoscopic evidence of gastric polyposis in antral area. The polyps disappeared four months after proton pump inhibitors were stopped.
Alqutub, Adel Nazmi, Masoodi, Ibrahim, Masoodi, I, Alqutub, AN   +3 more
core   +1 more source

High‐Current‐Density Acidic CO2 Electroreduction to Formic Acid Enabled by Multiscale Microenvironment Regulation Over Defect‐Rich Sn/SnOx

Advanced Science, EarlyView.
Acidic CO2 electroreduction to formic acid is enabled by integrating mixed Sn/SnOx nanoclusters, K+‐regulated interfacial solvation, and Janus wettability. Coordinated control of active sites, interfacial water, and gas‐liquid transport suppresses hydrogen evolution and delivers approximately 85% HCOOH Faradaic efficiency at 400 mA cm−2.
Qiaoqi Guo, Bowen Jiang, Le Huang, Kunyu Jiang, Rongrong Tang, Qinong Zhu, Huajun Feng, Mengyang Fan, Yijing Xia   +8 more
wiley   +1 more source

Comparison of the Efficacy of Proton Pump Inhibitors and Potassium-Competitive Acid Blockers in Achieving and Maintaining Endoscopic Remission in Erosive Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis

Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: to compare the efficacy of proton pump inhibitors and potassium-competitive acid blockers (P-CABs) in achieving and maintaining endoscopic remission in erosive gastroesophageal reflux disease.Materials and methods.
P. G. Ermishina, A. S. Trukhmanov, A. A. Makushina, O. A. Storonova, A. V. Paraskevova, V. T. Ivashkin   +5 more
doaj   +1 more source