Results 101 to 110 of about 249,684 (338)
Outcomes and Prognostic Factors for Locally Recurrent Rectal Cancer Treated With Proton Beam Therapy
Purpose: Our objective was to report the outcome and prognostic factors for patients with locally recurrent rectal cancer (LRRC) treated with proton beam therapy (PBT) at our institution.
Yoshiaki Takagawa, MD+8 more
doaj
Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen+9 more
wiley +1 more source
Objective: To verify the accuracy of an independent dose calculation method, as incorporated into an in-house developed treatment planning system (TPS), for performing quality assurance of dose distributions delivered to a water phantom planned by a ...
Michael F. Moyers+10 more
doaj
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth+2 more
wiley +1 more source
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia+7 more
wiley +1 more source
Thermoresponsive BrushGel Microcarriers for Efficient Cell Expansion and Enzyme‐Reduced Harvesting
Askari et al, report on temperature‐responsive microcarriers to minimize enzyme use and cost in dynamic cultures. Abstract Scaling up cell therapy requires efficient expansion of high‐quality cells. Microcarrier(MC)‐based systems offer high surface‐to‐volume ratios and reduce culture media usage.
Esfandyar Askari+9 more
wiley +1 more source
Letter: Proton beam therapy for acromegaly. [PDF]
T. D. R. Hockaday+3 more
openalex +1 more source
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto+2 more
wiley +1 more source
Background. This study was designed to compare the quality assurance (QA) results of four dosimetric tools used for intensity modulated radiation therapy (IMRT) and to suggest universal criteria for the passing rate in QA, irrespective of the dosimetric ...
Son Jaeman+9 more
doaj +1 more source