Results 101 to 110 of about 5,021,050 (358)

Recent Progress in Pencil Beam Scanning FLASH Proton Therapy: A Narrative Review [PDF]

arXiv, 2022
Background and Objective: Recent experimental studies using ultra-high dose rate radiation therapy (FLASH-RT) have shown improved normal tissue sparing and comparable tumor control compared to conventional dose rate RT. Pencil beam scanning (PBS) proton therapy with superior dosimetry characteristics has begun to draw attention to the delivery of ...
arxiv  

A Python package for fast GPU‐based proton pencil beam dose calculation

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Open‐source GPU‐based Monte Carlo (MC) proton dose calculation algorithms provide high speed and unparalleled accuracy but can be complex to integrate with new applications and remain slower than GPU‐based pencil beam (PB) methods, which sacrifice some physical accuracy for sub‐second plan calculation.
Mahasweta Bhattacharya, Calin Reamy, Heng Li, Junghoon Lee, William T. Hrinivich   +4 more
wiley   +1 more source

Temporal dynamics of lymphocytes in prostate cancer patients treated with proton therapy

Frontiers in Oncology
Radiotherapy can be both immunosuppressive and immunostimulatory. Radiation-induced lymphopenia (RIL) is an ongoing challenge in cancer treatment.
Sarah Salih Al-Hamami, Samuel Kurucz, Vladimír Vondráček, Vladimír Pekar, Michal Andrlík, Kateřina Dědečková, Iva Benešová, Alexandra Haas, Barbora Ondrová, Andrea Pasztorová, Pavel Vítek, Jiří Kubeš   +11 more
doaj   +1 more source

Proton beam therapy is a safe and feasible treatment for patients with second primary lung cancer after lung resection

Thoracic Cancer, 2019
Background The purpose of the present study was to retrospectively evaluate the safety and efficacy of proton beam therapy (PBT) in patients with second primary lung cancer after lung resection.
Takashi Ono, Tatsuya Nakamura, Yusuke Azami, Motohisa Suzuki, Hitoshi Wada, Yasuhiro Kikuchi, Masao Murakami, Kenji Nemoto   +7 more
doaj   +1 more source

Beamlet-free optimization for Monte Carlo based treatment planning in proton therapy [PDF]

arXiv, 2023
Background: Dose calculation and optimization algorithms in proton therapy treatment planning often have high computational requirements regarding time and memory. This can hinder the implementation of efficient workflows in clinics and prevent the use of new, elaborate treatment techniques aiming to improve clinical outcomes like robust optimization ...
arxiv  

Proton therapy for adults with mediastinal lymphomas: the International Lymphoma Radiation Oncology Group guidelines.

Blood, 2018
Among adult lymphoma survivors, radiation treatment techniques that increase the excess radiation dose to organs at risk (OARs) put patients at risk for increased side effects, especially late toxicities.
B. Dabaja, Bradford S Hoppe, J. Plastaras, W. Newhauser, Katerina Rosolova, S. Flampouri, R. Mohan, N. Mikhaeel, Y. Kirova, L. Specht, J. Yahalom   +10 more
semanticscholar   +1 more source

Machine stability and dosimetry for ultra‐high dose rate FLASH radiotherapy human clinical protocol

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The FLASH effect, induced by ultra‐high dose rate (UHDR) irradiations, offers the potential to spare normal tissue while effectively treating tumors. It is important to achieve precise and accurate dose delivery and to establish reliable detector systems, particularly for clinical trials needed to help the clinical transfer of FLASH‐
Patrik Gonçalves Jorge, Reiner Geyer, Rémy Kinj, Luis Schiappacasse, Wendy Jeanneret‐Sozzi, Jean Bourhis, Fernanda Herrera, François Bochud, Claude Bailat, Raphaël Moeckli   +9 more
wiley   +1 more source

Optimization of the planning process with an in-house treatment information, management, and planning system

Radiation Medicine and Protection, 2022
Objective: To describe the major categories of components of an in-house treatment information, management, and planning system (TIMPS®) that were designed and built to optimize the planning process.
Michael F. Moyers, James Lin, Jie Li, Hongliang Chen, Zhuangming Shen   +4 more
doaj  

DPM as a radiation transport engine for PRIMO

Radiation Oncology, 2018
Background PRIMO is a dose verification system based on the general-purpose Monte Carlo radiation transport code penelope, which implements an accurate physics model of the interaction cross sections and the radiation transport process but with low ...
Miguel Rodriguez, Josep Sempau, Christian Bäumer, Beate Timmermann, Lorenzo Brualla   +4 more
doaj   +1 more source

Technologies for Delivery of Proton and Ion Beams for Radiotherapy

, 2013
Recent developments for the delivery of proton and ion beam therapy have been significant, and a number of technological solutions now exist for the creation and utilisation of these particles for the treatment of cancer.
Alonso, Jose, Holder, David, MacKay, Ranald, Owen, Hywel   +3 more
core   +1 more source