Results 161 to 170 of about 5,021,050 (358)

Skull base chordoma treated with proton therapy: A systematic review

open access: yesSurgical neurology international, 2019
Background: Chordoma located in the skull base is usually a challenging surgical condition. It is often not possible to achieve gross total resection. Residual tumors have been treated with adjuvant focal radiation therapy employing high-energy particles
M. Alahmari, Y. Temel
semanticscholar   +1 more source

Development of Itaconate Polymers Microparticles for Intracellular Regulation of Pro‐Inflammatory Macrophage Activation

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops itaconate‐based polymer microparticles (IA‐MPs) for macrophage‐targeted intracellular delivery, overcoming the limitations of traditional itaconate administration. IA‐MPs achieve controlled release through phagocytosis, reducing pro‐inflammatory cytokine expression and reprogramming macrophage metabolism toward glycolysis.
Kaitlyn E. Woodworth   +10 more
wiley   +1 more source

Advanced Materials for Biological Field‐Effect Transistors (Bio‐FETs) in Precision Healthcare and Biosensing

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how advanced materials enhance Bio‐FETs for precision healthcare and biosensing. It covers their working principles, surface functionalization, and ultra‐sensitive detection capabilities. The integration of flexible designs, AI, and IoT for real‐time monitoring is discussed, along with challenges like material reproducibility and ...
Minal Pandey   +5 more
wiley   +1 more source

Correction: Feasibility of linac-based fractionated stereotactic radiotherapy and stereotactic radiosurgery for patients with up to ten brain metastases

open access: yesRadiation Oncology, 2023
Masanori Hirata   +15 more
doaj   +1 more source

Dosimetric comparison of gantry and horizontal fixed‐beam proton therapy treatment plans for base of skull chordoma

open access: yesJournal of Medical Radiation Sciences
Introduction Australia's first proton beam therapy (PBT) centre will house a fixed‐beam room and two gantry rooms. As the only PBT facility in Australia for at least the short term, there is a need to efficiently allocate treatment appointments between ...
Emma Shierlaw   +4 more
doaj   +1 more source

Protons or megavoltage X-rays as boost therapy for patients irradiated for localized prostatic carcinoma an early phase I/II comparison [PDF]

open access: bronze, 1983
J. A. Duttenhaver   +8 more
openalex   +1 more source

Proton therapy for paediatric medulloblastoma [PDF]

open access: yesThe Lancet Oncology, 2016
Radiation oncology has changed greatly in recent decades, driven mainly by technical advances in treatment planning and delivery. Proton radiation therapy is a further advance; however, it is more expensive than traditional photon therapy and its critics argue that its costs are not justifi ed.
openaire   +3 more sources

Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response

open access: yesAdvanced Healthcare Materials, EarlyView.
In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim   +11 more
wiley   +1 more source

Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
Lipid nanoparticles (LNPs) have rapidly become the delivery system of choice for RNA therapeutics. Here, a rational design approach is taken to improve the effectiveness of LNPs based on an ionizable thioether lipid library. The incorporation of unsaturated tails and bulkier, hydrophobic head groups significantly enhances their functionality and ...
Eleni Samaridou   +4 more
wiley   +1 more source

Identification of Induced Radionuclides Produced from Dental Metals in Proton Beam Therapy for Head and Neck Cancer

open access: yesAdvances in Radiation Oncology, 2023
Purpose: To identify the induced radionuclides produced from dental metals in proton beam therapy and investigate the accuracy of the Monte Carlo (MC) simulation by comparing the measured radioactivity.
Ryohei Kato, MS   +5 more
doaj  

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