Results 21 to 30 of about 5,053,091 (357)

Proton Therapy Reduces the Likelihood of High-Grade Radiation-Induced Lymphopenia in Glioblastoma Patients: Phase II Randomized Study of Protons vs. Photons.

Neuro-Oncology, 2020
BACKGROUND We investigated differences in radiation-induced grade 3+ lymphopenia (G3+L), defined as an absolute lymphocyte count (ALC) nadir of
R. Mohan, Amy Y. Liu, P. Brown, A. Mahajan, J. Dinh, C. Chung, S. McAvoy, M. McAleer, Steven H. Lin, Jing Li, A. Ghia, Cong Zhu, E. Sulman, J. D. de Groot, A. Heimberger, S. McGovern, C. Grassberger, H. Shih, S. Ellsworth, D. Grosshans   +19 more
semanticscholar   +1 more source

Impact of proton therapy on antitumor immune response

Scientific Reports, 2021
Radiotherapy delivered using photons induces an immune response that leads to modulation of the tumor microenvironment. Clinical studies are ongoing to evaluate immune checkpoint inhibitors in association with photon radiotherapy. At present, there is no
C. Mirjolet, A. Nicol, E. Limagne, Carole Mura, C. Richard, V. Morgand, M. Rousseau, R. Boidot, F. Ghiringhelli, G. Noel, H. Burckel   +10 more
semanticscholar   +1 more source

Technical assessment of the NDI Polaris Vega optical tracking system

Radiation Oncology, 2021
The Polaris product line from Northern Digital Inc. is well known for accurate optical tracking measurements in research and medical environments. The Spectra position sensor, to date often found in image guided radiotherapy suites, has however reached ...
Giovanni Fattori, Antony John Lomax, Damien Charles Weber, Sairos Safai   +3 more
doaj   +1 more source

Roadmap: proton therapy physics and biology

Physics in Medicine and Biology, 2020
The treatment of cancer with proton radiation therapy was first suggested in 1946 followed by the first treatments in the 1950s. As of 2020, almost 200 000 patients have been treated with proton beams worldwide and the number of operating proton therapy (
H. Paganetti, C. Beltran, S. Both, L. Dong, J. Flanz, K. Furutani, C. Grassberger, D. Grosshans, A. Knopf, J. Langendijk, H. Nyström, K. Parodi, B. Raaymakers, C. Richter, G. Sawakuchi, J. Schippers, S. Shaitelman, K. Teo, J. Unkelbach, P. Wohlfahrt, A. Lomax   +20 more
semanticscholar   +1 more source

Consensus Statement on Proton Therapy for Prostate Cancer

International Journal of Particle Therapy, 2021
Proton therapy is a promising but controversial treatment in the management of prostate cancer. Despite its dosimetric advantages when compared with photon radiation therapy, its increased cost to patients and insurers has raised questions regarding its ...
C. Bryant, R. Henderson, R. Nichols, W. Mendenhall, B. Hoppe, C. Vargas, T. Daniels, C. Choo, R. Parikh, H. Giap, J. Slater, N. Vapiwala, W. Barrett, A. Nanda, M. Mishra, Seungtaek L. Choi, J. Liao, N. Mendenhall   +17 more
semanticscholar   +1 more source

Assessment of a Therapeutic X-ray Radiation Dose Measurement System Based on a Flexible Copper Indium Gallium Selenide Solar Cell

Sensors, 2022
Several detectors have been developed to measure radiation doses during radiotherapy. However, most detectors are not flexible. Consequently, the airgaps between the patient surface and detector could reduce the measurement accuracy.
Dong-Seok Shin, Tae-Ho Kim, Jeong-Eun Rah, Dohyeon Kim, Hye Jeong Yang, Se Byeong Lee, Young Kyung Lim, Jonghwi Jeong, Haksoo Kim, Dongho Shin, Jaeman Son   +10 more
doaj   +1 more source

Comparison of CBCT based synthetic CT methods suitable for proton dose calculations in adaptive proton therapy

Physics in Medicine and Biology, 2020
In-room imaging is a prerequisite for adaptive proton therapy. The use of onboard cone-beam computed tomography (CBCT) imaging, which is routinely acquired for patient position verification, can enable daily dose reconstructions and plan adaptation ...
A. Thummerer, P. Zaffino, A. Meijers, G. Marmitt, J. Seco, R. Steenbakkers, J. Langendijk, S. Both, M. Spadea, A. Knopf   +9 more
semanticscholar   +1 more source

A Systematic Review of Proton Therapy for the Management of Nasopharyngeal Cancer

International Journal of Particle Therapy, 2021
Purpose With improved technology, more patients with nasopharyngeal cancer (NPC) are receiving definitive treatment with proton therapy, which allows greater sparing of dose to normal tissues without compromising efficacy. As there is no randomized data,
Anna Lee, S. Kitpanit, M. Chilov, J. Langendijk, Jiade J. Lu, N. Lee   +5 more
semanticscholar   +1 more source

Successful treatment with proton beam therapy for a solitary sternal metastasis of breast cancer: a case report

Journal of Medical Case Reports, 2022
Background Breast cancer infrequently metastasizes to the sternum as solitary metastasis. We experienced successful treatment with proton beam therapy for a case of sternal metastasis of breast cancer.
Yojiro Ishikawa, Motohisa Suzuki, Hisashi Yamaguchi, Ichiro Seto, Masanori Machida, Yoshiaki Takagawa, Keiichi Jingu, Yasuyuki Kikuchi, Masao Murakami   +8 more
doaj   +1 more source

Proton Therapy and Gliomas: A Systematic Review

Radiation, 2021
Background: Gliomas are primary cerebral tumors. Radiation therapy plays a key role in their treatment but with a risk of toxicity associated with the dose to and volume of normal tissue that is irradiated.
I. Chambrelant, J. Eber, D. Antoni, H. Burckel, G. Noël, R. Auvergne   +5 more
semanticscholar   +1 more source