Results 51 to 60 of about 168,635 (283)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Proton Binding of Halloysite Nanotubes at Varied Ionic Strength: A Potentiometric Titration and Electrophoretic Mobility Study

open access: yesColloids and Interfaces
Proton binding (i.e., charging) isotherms of halloysite nanotubes (HNT) were determined from cycled acid-base potentiometric titrations in KCl solution at constant ionic strengths (0.01, 0.10, 1.00 mol dm−3). The isotherms measured in the pH cycle from 3
Bojana Katana, Duško Čakara
doaj   +1 more source

Solvent effects on glyphosate deprotonation: DFT theoretical studies

open access: yesChemical Physics Impact, 2023
To better understand the molecular structures of glyphosate in different solvents, we have studied several possible conformations, and their relative abundances, of glyphosate and its deprotonated forms, in acetone, acetonitrile, DMSO, water, ethanol ...
Alberto G. Albesa   +1 more
doaj   +1 more source

Proton–proton, anti-proton–anti-proton, proton–anti-proton correlations in Au + Au collisions measured by STAR at RHIC [PDF]

open access: yesThe European Physical Journal C, 2006
The analysis of two-particle correlations provides a powerful tool to study the properties of hot and dense matter created in heavy-ion collisions at ultra-relativistic energies. Applied to identical and non-identical hadron pairs, it makes the study of space-time evolution of the source in femtoscopic scale possible.
openaire   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Hydrogen Generation Catalyzed by Fluorinated Diglyoxime−Iron Complexes at Low Overpotentials [PDF]

open access: yes, 2012
Fe^(II) complexes containing the fluorinated ligand 1,2-bis(perfluorophenyl)ethane-1,2-dionedioxime (dAr^FgH_2; H = dissociable proton) exhibit relatively positive Fe^(II/I) reduction potentials.
Gray, Harry B.   +2 more
core   +1 more source

Inner-sphere complexation of cations at the rutile-water interface: A concise surface structural interpretation with the CD and MUSIC model [PDF]

open access: yes, 2009
Acid–base reactivity and ion-interaction between mineral surfaces and aqueous solutions is most frequently investigated at the macroscopic scale as a function of pH.
Hiemstra, T.   +3 more
core   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Protonation of apolar species: From Cl2H+ to (E)-NCCHCHCNH+ through computational investigations

open access: yesFrontiers in Astronomy and Space Sciences, 2023
Radioastronomy is a powerful tool for the discovery of molecules in space but it requires molecular species to be polar. The observation of apolar species can be however enabled by protonation, which occurs from reaction with the abundant H3+ ion ...
Silvia Alessandrini   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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