Simultaneous determination of protoporphyrin IX and magnesium protoporphyrin IX in Arabidopsis thaliana and Camellia sinensis using UPLC-MS/MS [PDF]
Plant Methods, 2023 Backgrounds Insertion of Mg2+ into protoporphyrin IX (PPIX) to produce magnesium-protoporphyrin IX (Mg-PPIX) was the first step toward chlorophyll biosynthesis, which not only imparts plants green pigmentation but underpins photosynthesis.
Chenyu Zhang +3 more
doaj +2 more sources
Protoporphyrin IX-induced phototoxicity: Mechanisms and therapeutics. [PDF]
Pharmacol Ther, 2023 Protoporphyrin IX (PPIX) is an intermediate in the heme biosynthesis pathway. Abnormal accumulation of PPIX due to certain pathological conditions such as erythropoietic protoporphyria and X-linked protoporphyria causes painful phototoxic reactions of the skin, which can significantly impact daily life.
Hussain Z +4 more
europepmc +3 more sources
Microneedle System Coated with Hydrogels Containing Protoporphyrin IX for Potential Application in Pharmaceutical Technology [PDF]
Methods and ProtocolsThe article aims to outline the potential of treating malignant skin cancer with microneedles covered with polymer layers containing a photosensitizer—protoporphyrin IX disodium salt (PPIX).
Beata Czarczynska-Goslinska +9 more
doaj +2 more sources
Gold Nanoparticles/Nanographene-Based 3D Sensors Integrated in Mini-Platforms for Thiamine Detection
Sensors, 2022 Vitamins are essential for sustaining daily activities and perform crucial roles in metabolism, such as preventing vascular events and delaying the development of diabetic nephropathy.
Damaris-Cristina Gheorghe +3 more
doaj +1 more source
Animal, 2023 Eggshell colour is the unique appearance and economically valuable trait of eggs, whereas the colour is often short of uniformity, especially in the blue-shelled breeds, hence, their pigment differences and molecular mechanism need clarity.
Huanhuan Wang +6 more
doaj +1 more source
A photosensitizing fusion protein with targeting capabilities
Biomolecular Concepts, 2022 The photodynamic treatment for antimicrobial applications or anticancer therapy relies on reactive oxygen species generated by photosensitizing molecules after absorption of visible or near-infrared light.
Bruno Stefano +8 more
doaj +1 more source
Mechanisms associated with the depigmentation of brown eggshells: a review
Poultry Science, 2021 : Eggshell color is an important shell quality trait that influences consumer preference. It is also of particular importance with respect to sexual signaling and the physiological and mechanical properties of shell pigment.
Ming-Yuan Lu +6 more
doaj +1 more source
Frontiers in Plant Science, 2020 Wheat (Triticum aestivum L.) is one of the most important crops in the world. Chlorophyll plays a vital role in plant development and crop improvement and further determines the crop productivity to a certain extent.
Chaojie Wang +9 more
doaj +1 more source
Mechanisms of Vesicular Stomatitis Virus Inactivation by Protoporphyrin IX, Zinc-Protoporphyrin IX, and Mesoporphyrin IX [PDF]
Antimicrobial Agents and Chemotherapy, 2017 ABSTRACT Virus resistance to antiviral therapies is an increasing concern that makes the development of broad-spectrum antiviral drugs urgent. Targeting of the viral envelope, a component shared by a large number of viruses, emerges as a promising strategy to overcome this problem.
Cruz-Oliveira, Christine +9 more
openaire +3 more sources
Alectinib treatment improves photodynamic therapy in cancer cell lines of different origin
BMC Cancer, 2021 Background Photodynamic therapy with a photosensitizer such as protoporphyrin-IX, a light sensitive metabolite of heme synthesis, is a highly selective treatment for various carcinomas.
Bernhard Gillissen +3 more
doaj +1 more source