Chromophore-Targeting Precision Antimicrobial Phototherapy
Phototherapy, encompassing the utilization of both natural and artificial light, has emerged as a dependable and non-invasive strategy for addressing a diverse range of illnesses, diseases, and infections.
Sebastian Jusuf, Pu-Ting Dong
doaj +1 more source
Zinc protoporphyrin binding to telomerase complexes and inhibition of telomerase activity*
Zinc protoporphyrin (ZnPP), a naturally occurring metalloprotoporphyrin (MPP), is currently under development as a chemotherapeutic agent although its mechanism is unclear.
Zhaowen Zhu +8 more
doaj +1 more source
Relationship between blood Lead status and anemia in Ugandan children with malaria infection
Background In Uganda, childhood anemia remains a health challenge and is associated with malaria infection as well as iron deficiency. Iron deficiency is intertwined with nutritional status, age and other comorbidities including helminths and Lead ...
Ambrose Mukisa +4 more
doaj +1 more source
Manganese [III] Tetrakis [5,10,15,20]-Benzoic Acid Porphyrin Reduces Adiposity and Improves Insulin Action in Mice with Pre-Existing Obesity. [PDF]
The superoxide dismutase mimetic manganese [III] tetrakis [5,10,15,20]-benzoic acid porphyrin (MnTBAP) is a potent antioxidant compound that has been shown to limit weight gain during short-term high fat feeding without preventing insulin resistance ...
Jonathan R Brestoff +9 more
doaj +1 more source
Eggshell spottiness reflects maternally transferred antibodies in blue tits. [PDF]
Blue-green and brown-spotted eggshells in birds have been proposed as sexual signals of female physiological condition and egg quality, reflecting maternal investment in the egg. Testing this hypothesis requires linking eggshell coloration to egg content,
Marie-Jeanne Holveck +6 more
doaj +1 more source
Formation of meso, N-diphenylprotoporphyrin IX by an aerobic reaction of phenylhydrazine with oxyhemoglobins. [PDF]
Administration of phenylhydrazine to rabbits resulted in the denaturation of hemoglobins in erythrocytes, causing the formation of intracellular precipitates known as Heinz bodies, severe hemolytic anemia, and reticulocytosis.
Abe, Tadashi +8 more
core +1 more source
Metalloporphyrins inactivate caspase-3 and -8 [PDF]
Activation of caspases represents one of the earliest biochemical indicators for apoptotic cell death. Therefore, measurement of caspase activity is a widely used and generally accepted method to determine apoptosis in a wide range of in vivo and in ...
Blumenthal, Signe B. +8 more
core +1 more source
A novel high-content immunofluorescence assay as a tool to identify at the single cell level γ-globin inducing compounds [PDF]
The identification of drugs capable of reactivating γ-globin to ameliorate β-thalassemia and Sickle Cell anemia is still a challenge, as available γ-globin inducers still have limited clinical indications.
Antonella Ronchi +14 more
core +7 more sources
Erythrocyte zinc protoporphyrin [PDF]
In iron deficiency and lead poisoning, the enzyme ferrochelatase catalyzes the incorporation of zinc, instead of iron, into protoporphyrin IX, resulting in the formation of zinc protoporphyrin (ZPP). In healthy blood donors, there is a good inverse correlation between serum ferritin and ZPP levels.
openaire +2 more sources
Anaemia, iron deficiency and vitamin A status among school-aged children in rural Kazakhstan. [PDF]
OBJECTIVES: To investigate the prevalence of anaemia and iron deficiency and vitamin A status among school-aged children in rural Kazakhstan and identify factors associated with anaemia in this population. DESIGN: A cross-sectional design.
Alnazarova, Akmaral +9 more
core +1 more source

