Results 21 to 30 of about 1,927 (199)
Erythrocyte zinc protoporphyrin [PDF]
Kidney International, 1999 In iron deficiency and lead poisoning, the enzyme ferrochelatase catalyzes the incorporation of zinc, instead of iron, into protoporphyrin IX, resulting in the formation of zinc protoporphyrin (ZPP). In healthy blood donors, there is a good inverse correlation between serum ferritin and ZPP levels.
openaire +2 more sources
Triplet state magnetic resonance and fluorescence spectroscopy of metal-substituted hemoglobins. [PDF]
, 1997 Fluorescence detected magnetic resonance (FDMR) spectra detected at 596 nm of zinc-substituted hemoglobins at 4.2 K show a split D-E transition, which is not observed for zinc protoporphyrins ligated by methylimidazole in glasses.
Schaafsma, T.J., Polm, M.W.
core +1 more source
Experiments with Protoporphyrin
Experimental Biology and Medicine, 1946 Summary1. A simple method for the preparation of protoporphyrin from blood is described. 2. White rats were injected subcutaneously with protoporphyrin and were found to excrete greatly increased amounts of protoporphyrin in the feces. No urinary protoporphyrin nor increase of urinary coproporphyrin excretion following the injection was noted.
openaire +2 more sources
Biological and Pharmaceutical Bulletin, 1993 The effect of protoporphyrin (PP) administration on the activities of enzymes related to and/or involved in lipid peroxidation and on the content of reduced glutathione (GSH) was investigated in rat liver. PP, at an intravenous dose of 20 mg/kg, increased GSH content, caused a weak suppression of NADPH-cytochrome c reductase activity and a slight ...
IMAI, Kimie +3 more
openaire +3 more sources
mBio, 2013 Staphylococcus aureus is a significant cause of infections worldwide and is able to utilize aerobic respiration, anaerobic respiration, or fermentation as the means by which it generates the energy needed for proliferation.
Neal D. Hammer +6 more
doaj +1 more source
Effects of Mono- and Dicapsaicinoid Functionalization on the Physicochemical Properties and Antimicrobial Photodynamic Activity of Protoporphyrin IX. [PDF]
ChemMedChemCapsaicin functionalization of Protoporphyrin IX influences aggregation behavior, lipophilicity, and photodynamic activity. A monosubstituted derivative exhibits enhanced antimicrobial photoinactivation of Staphylococcus aureus, whereas increased functionalization does not improve efficacy.
Cunha IVD +10 more
europepmc +2 more sources
Molecular Medicine, 2013 X-linked protoporphyria (XLP) (MIM 300752) is a recently recognized erythropoietic porphyria due to gain-of-function mutations in the erythroid-specific aminolevulinate synthase gene (ALAS2).
David F. Bishop +3 more
doaj +1 more source
Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation
Advanced Science, EarlyView.Dynamic supramolecular assembly reshapes targeted protein degradation by coordinating modular degrader construction, delivery, functional integration, and intracellular assembly or activation across proteasomal, endosomal–lysosomal, and autophagy–lysosomal pathways.
Kongjun Liu +8 more
wiley +1 more source
Journal of Photochemistry and PhotobiologyMetallo-protoporphyrin IX (PpIX) offer a versatile platform for engineering photoresponsive proteins (EPrPs), yet their photophysical and photochemical properties upon interaction with proteins remains insufficiently characterized.
Omar Castillo +3 more
doaj +1 more source
Advanced Science, EarlyView.A bioactive self‐delivering SNAP‐TAC platform responds to tumor‐associated cathepsin B and glutathione, enabling in situ bioorthogonal synthesis of a BRD4‐degrading proteolysis‐targeting chimera within the tumor microenvironment. The resulting BRD4 degradation and PD‐L1 downregulation synergize with photodynamic therapy‐induced immunogenic cell death ...
Shiqin Jian +14 more
wiley +1 more source