Results 11 to 20 of about 1,847 (196)

Prolonged Allogeneic Islet Graft Survival by Protoporphyrins

open access: yesCell Transplantation, 2005
Transplantation of islets of Langerhans in patients with type 1 diabetes allows for improved metabolic control and insulin independence. The need for chronic immunosuppression limits this procedure to selected patients with brittle diabetes.
Antonello Pileggi   +9 more
doaj   +2 more sources

Determination of selected protoporphyrins in Parma ham with use of 5,10,15,20-tetra(4-hydroxyphenyl)porphyrin as a surrogate standard in the recovery study

open access: yesActa Chimica Slovenica, 2014
A high-performance liquid chromatographic analysis for the determination of hemin, protoporphyrin IX (PPIX), and zinc(II)protoporphyrin IX (Zn(II)PPIX) in Parmaham was developed.
Hannelore De Maere   +6 more
doaj   +1 more source

Relationship between blood Lead status and anemia in Ugandan children with malaria infection

open access: yesBMC Pediatrics, 2020
Background In Uganda, childhood anemia remains a health challenge and is associated with malaria infection as well as iron deficiency. Iron deficiency is intertwined with nutritional status, age and other comorbidities including helminths and Lead ...
Ambrose Mukisa   +4 more
doaj   +1 more source

Zinc protoporphyrin binding to telomerase complexes and inhibition of telomerase activity*

open access: yesPharmacology Research & Perspectives, 2021
Zinc protoporphyrin (ZnPP), a naturally occurring metalloprotoporphyrin (MPP), is currently under development as a chemotherapeutic agent although its mechanism is unclear.
Zhaowen Zhu   +8 more
doaj   +1 more source

Eggshell spottiness reflects maternally transferred antibodies in blue tits. [PDF]

open access: yesPLoS ONE, 2012
Blue-green and brown-spotted eggshells in birds have been proposed as sexual signals of female physiological condition and egg quality, reflecting maternal investment in the egg. Testing this hypothesis requires linking eggshell coloration to egg content,
Marie-Jeanne Holveck   +6 more
doaj   +1 more source

Light-induced release of protoporphyrin, but not of zinc protoporphyrin, from erythrocytes in a patient with greatly elevated erythrocyte protoporphyrin [PDF]

open access: yesBlood, 1983
A patient with greatly increased erythrocyte protoporphyrin, but normal porphyrins in urine and feces, is described. The patient later developed a malignant lymphoma, and the reason why she accumulated protoporphyrin in her erythrocytes is not known. The protoporphyrin in the erythrocytes consisted of two types of protoporphyrin, free protoporphyrin ...
S, Sandberg   +3 more
openaire   +3 more sources

Protoporphyrin Treatment Modulates Susceptibility to Experimental Autoimmune Encephalomyelitis in miR-155-Deficient Mice.

open access: yesPLoS ONE, 2015
We previously identified heme oxygenase 1 (HO-1) as a specific target of miR-155, and inhibition of HO-1 activity restored the capacity of miR-155-/- CD4+ T cells to promote antigen-driven inflammation after adoptive transfer in antigen-expressing ...
Jinyu Zhang, Michel Y Braun
doaj   +1 more source

Inhibition of plasminogen activator inhibitor-1 expression in vascular smooth muscle cells by protoporphyrins through a heme oxygenase-independent mechanism

open access: yes, 2008
Heme oxygenase-1 (HO-1), a rate-limiting enzyme in heme catabolism, has been shown to play a regulatory role in the expression of plasminogen activator inhibitor-1 (PAI-1), a risk factor for vascular disease.
Schafer, Andrew I., Long, Xilin
core   +2 more sources

Data on characterization of metalloporphyrin-mediated HO-1 and DAF induction in rat glomeruli and podocytes

open access: yesData in Brief, 2019
The data presented pertain to a research article titled ''Heme Oxygenase 1 Up-Regulates Glomerular Decay Accelerating Factor Expression and Minimizes Complement Deposition and Injury'' (Detsika et al., 2016).
Pu Duann, Pei-Hui Lin, Elias A. Lianos
doaj   +1 more source

A Deep‐Red‐Absorbing Osmium(II) Complex as a Photosensitizer for Photodynamic Therapy Inducing Immunogenic Cell Death

open access: yesAngewandte Chemie, EarlyView.
A deep‐red‐excited osmium(II) photosensitizer (Os2) induces immunogenic cell death (ICD) under 740 nm irradiation and triggers robust anti‐tumor immune responses both in vitro and in vivo. ABSTRACT Immunogenic cell death (ICD), which converts tumor cells into their own vaccine, plays a pivotal role in the development of novel anticancer therapies. Here,
Yiyi Zhang   +12 more
wiley   +2 more sources

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