We previously identified heme oxygenase 1 (HO-1) as a specific target of miR-155, and inhibition of HO-1 activity restored the capacity of miR-155-/- CD4+ T cells to promote antigen-driven inflammation after adoptive transfer in antigen-expressing ...
Jinyu Zhang, Michel Y Braun
doaj +1 more source
Heme oxygenase 1 is differentially involved in blood flow-dependent arterial remodeling: role of inflammation, oxidative stress, and nitric oxide [PDF]
Heme oxygenase 1 is induced by hemodynamic forces in vascular smooth muscle and endothelial cells. We investigated the involvement of heme oxygenase 1 in flow (shear stress)-dependent remodeling.
A. Caillon +7 more
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A review of the relationship between eggshell colour and water vapour conductance [PDF]
This review brings together the available literature that examines the effect of variations in pigmentation on the gas conductance of avian eggshells. Pheasant and Houbara bustard eggs provide some evidence that shell abnormalities can impact upon colour
Baggott G.K. +14 more
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UK experience of liver transplantation for erythropoietic protoporphyria [PDF]
Erythropoietic protoporphyria (EPP) is characterised by excess production of free protoporphyrin from the bone marrow, most commonly due to deficiency of the enzyme ferrochelatase.
A Dobozy +34 more
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Subunit-Selective Interrogation of CO Recombination in Carbonmonoxy Hemoglobin by Isotope-Edited Time-Resolved Resonance Raman Spectroscopy [PDF]
Hemoglobin (Hb) is an allosteric tetrameric protein made up of αβ heterodimers. The α and β chains are similar, but are chemically and structurally distinct. To investigate dynamical differences between the chains, we have prepared tetramers in which the
Balakrishnan, Gurusamy +5 more
core +2 more sources
The data presented pertain to a research article titled ''Heme Oxygenase 1 Up-Regulates Glomerular Decay Accelerating Factor Expression and Minimizes Complement Deposition and Injury'' (Detsika et al., 2016).
Pu Duann, Pei-Hui Lin, Elias A. Lianos
doaj +1 more source
Redox control of multidrug resistance and Its possible modulation by antioxidants [PDF]
Clinical efficacy of anticancer chemotherapies is dramatically hampered by multidrug resistance (MDR) dependent on inherited traits, acquired defence against toxins, and adaptive mechanisms mounting in tumours.
Cort, A. +4 more
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Resonance Raman Interrogation of the Consequences of Heme Rotational Disorder in Myoglobin and its Ligated Derivatives [PDF]
Resonance Raman spectroscopy is employed to characterize heme site structural changes arising from conformational heterogeneity in deoxyMb and ligated derivatives, i.e., the ferrous CO (MbCO) and ferric cyanide (MbCN) complexes.
Kincaid, James R. +2 more
core +3 more sources
Iron deficiency, cell-mediated immunity and infection among 6-36 month old children living in rural Togo [PDF]
Relationships between iron deficiency, cell-mediated immunity (CMI) and morbidity were studied in 220 children in rural south Togo. Iron deficiency was defined by abnormal values of at least two biochemical indicators of iron status viz.
Aplogan, A. +6 more
core +1 more source
Labelling in vivo and chirality of griseofulvin-derived N-alkylated protoporphyrins [PDF]
A H Gibbs +3 more
core +2 more sources

