Results 51 to 60 of about 226,361 (267)

Perancangan User Interface dan User Experience Aplikasi Klinik Gigi Menggunakan Metode Design Thinking

Jurnal Saintekom
Klinik Gigi drg. Ema Medika so far still provides services to patients manually and keeps medical records using paper documents. This causes data invalidity and sometimes the confidentiality of patient data cannot be maintained properly.
Dhea Putri Salsabila, Risqy Siwi Pradini, Ahsanun Naseh Khudori   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

MODELING, DYNAMIC AND THERMAL ANALYSIS OF THE PROTOTYPE MAGNETORHEOLOGICAL CLUTCH [PDF]

Scientific Journal of Silesian University of Technology. Series Transport, 2014
This paper presents the complex results concerning the prototype clutch with magnetorheological (MR) fluid. The obtained characteristics depicts the dependencies between the clutch’s torque and: the intensity of the magnetic field induced by the coil ...
Jerzy BAJKOWSKI
doaj  

NewRadial: Challenging scales and standards of humanities scholarship through new knowledge environment prototypes

Digital Studies, 2015
Even though large aggregations of humanities data are emerging through the efforts of significant federations, the larger the collection, the more difficult it is for large-scale standards to effectively account for and relate the complex variety of data
Jon Saklofske, Jon Saklofske
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

MOTION STUDY OF A WHEELCHAIR PROTOTYPE FOR DISABLED PEOPLE [PDF]

Fiabilitate şi Durabilitate, 2015
In this paper is presented the design and experimental prototype of a wheelchair for disabled people. Design solution proposed to be implemented uses two reduction gears motors and a mechanical transmission with chains.
Ionut GEONEA, Nicolae DUMITRU
doaj  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Smart Governance System’s Design to Monitor the Commitments of Bio-Business Licensing in Indonesia

Information
Some business license commitments in online single submission (OSS) application currently only consist of an independent statement from the business actor, and there is no time limit for fulfilling the license, especially for low-risk bio-business ...
Muhammad Mahreza Maulana, Arif Imam Suroso, Yani Nurhadryani, Kudang Boro Seminar   +3 more
doaj   +1 more source