Results 71 to 80 of about 217,132 (268)

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

IPMC-Based Purcell’s Three-Link Swimmer: Simulations and Experiments at Low-Reynolds Conditions

open access: yesActuators
The Purcell’s swimmer, consisting of three links with two one-degree-of-freedom joints as defined by Edward M. Purcell, has been studied by several authors since its introduction in 1977.
Cristina Nuevo-Gallardo   +3 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Effective Collaboration Research Project on IT Solution for Automatic Measurement of Timber Assortment [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2019
This paper deals with experience about the research project development with industry for the solution of specific problem. Nowadays most of higher educational institutions are particularly interested in implementing joint projects with industry, sharing
Ingus Mitrofanovs, Marita Cekule
doaj  

Peningkatan Jumlah Prototipe Produk Hasil Riset Universitas Andalas

open access: yesWarta Pengabdian Andalas, 2020
Innovation products are new ideas and ideas generated, one of the results of research.Universities are limited to only lead to the results of research and publications.
Cesar Welya Refdi, Wenny Surya Murtius
doaj   +1 more source

Phonetic prototypes [PDF]

open access: yesPerception & Psychophysics, 1982
Speech perception may be viewed as a phonetic categorization task in which the listener assigns incoming sounds to various phonetic categories. The present experiment tests two classes of models of phonetic categorization: (1) models in which the listener has a threshold or boundary between alternative categories vs.
openaire   +2 more sources

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Prototyping for Digital Innovation: Investigating the Impact of Digital Technology on Prototyping Elements

open access: yesAdministrative Sciences
Prototyping is an important part of any development activity since it supports communication and knowledge creation among the members of the developing organization.
Johan Wenngren, Aya Rizk
doaj   +1 more source

Research Prototypes

open access: yesArchives of Design Research, 2017
Background Prototyping has become a key research tool in product and interaction design during the last twenty years. There is a growing debate about its processes, objectives, qualities, and types. This paper contributes to this discussion by distinguishing research prototypes from design prototypes and industrial prototypes, and by analyzing debate ...
Koskinen, I, Frens, J
openaire   +3 more sources

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy