Results 61 to 70 of about 1,432,245 (303)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

The PANDA GEM-based TPC Prototype

open access: yes, 2010
We report on the development of a GEM-based TPC prototype for the PANDA experiment. The design and requirements of this device will be illustrated, with particular emphasis on the properties of the recently tested GEM-detector, the characterization of ...
A. Winnebeckd   +43 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Composite materials reinforced with ceramic waste and matrix of unsaturated polyester for applications in the automotive industry

open access: yesDyna, 2020
In the present investigation an alternative of recycling was evaluated for the residues derived from defective pieces of the ceramic industry, harnessing them as reinforcement in composite materials for the manufacture of parts used in the automotive ...
Jorge Antonio Velasco Parra   +2 more
doaj   +1 more source

Design of Prototype Dynamic Ac Power Machine with Equivalent Circuit Modeling (Torque Speed Curve of Induction Motor 1,1, Kw) [PDF]

open access: yes, 2017
Squirrel cage induction motors are widely used in electric motor drives due to their satisfactory mechanical characteristics (torque, current, overloading) and small dimensions, as well as their low price.
Abidin, Z. (Zainal), Adam, A. (Adam)
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

A Prototype Model of Stock Exchange

open access: yes, 1997
A prototype model of stock market is introduced and studied numerically. In this self-organized system, we consider only the interaction among traders without external influences.
  +10 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

BlogForever D2.4: Weblog spider prototype and associated methodology [PDF]

open access: yes, 2013
The purpose of this document is to present the evaluation of different solutions for capturing blogs, established methodology and to describe the developed blog spider ...
Banos, V.   +6 more
core   +1 more source

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