Results 91 to 100 of about 610,579 (177)

Multiscale computational profiling of a promising carbapenemase inhibitor: from binding dynamics to quantum reactivity [PDF]

Exploration of Drug Science
Aim: The prevalence of multidrug-resistant “superbugs”, particularly Acinetobacter baumannii and Klebsiella pneumoniae, is a menacing phenomenon in society, rendering last-resort antibiotics increasingly suboptimal and ineffective.
Ayuba Olanrewaju Mustapha, Adefunke Jelilat Adeniyi, Mazeedah Eniola Alaka, Sulyman Olalekan Ibrahim, Yusuf Oloruntoyin Ayipo   +4 more
doaj   +1 more source

β-catenin Mutations Are Not Involved in Early-stage Hepatocarcinogenesis Induced by Protoporphyrinogen Oxidase Inhibitors in Mice

, 2017
We previously reported the contribution of constitutive androstane receptor (CAR) in cytotoxicity-related hepatocarcinogenesis induced by oxadiazon (OX) or acifluorfen (ACI), two pesticides categorized as protoporphyrinogen oxidase (PROTOX) inhibitors ...
Kaoru Inoue, Miwa Takahashi, Makoto Shibutani, Kazunori Kuwata, Yukio Kodama, Ryohei Ichimura, Midori Yoshida   +6 more
core   +1 more source

Molecular Docking and Pharmacokinetics Analysis of Phytochemicals from Piper caninum as Dengue NS2B-NS3 Protease Inhibitors

Journal of Tropical Life Science
Dengue fever affects 390 million people each year. Currently, there is no specific medicine to treat this disease. Thus, the search for potential NS2B-NS3 protease inhibitors has attracted increasing research interest.
Nur Farhana Mustafa, Kian Kai Cheng, Siti Aisyah Razali, Muhammad Helmi Nadri   +3 more
doaj   +1 more source

Computational Approaches for linoleic acid, (10E,13E)-octadeca-10,13-dienoic acid, or its isomer: 10,13-octadecadienoic acid as Antibacterial Inhibitors [PDF]

ERU Research Journal
The virtual study of the bioactive UFAs, linoleic acid (A), (10E,13E)-octadeca-10,13-dienoic acid (B), and its isomer 10,13-octadecadienoic acid (B-1), was assessed against two bacterial PDB IDs: 3NKH (Staphylococcus aureus) and 3QVL (K. pneumoniae). The
Sherouk Hussein Sweilam
doaj   +1 more source

Atividade da enzima acetolactato sintase em Euphorbia heterophylla com resistência múltipla aos herbicidas inibidores da ALS e da protox [PDF]

, 2013
The objective of this study was to determine the activity of the enzyme acetolactate synthase in biotypes of wild poinsettia (Euphorbia heterophylla) with multiple resistance to ALS- and Protox- inhibitors in the presence and absence of imazapyr ...
Xavier, Elouize, Pagnocelli Junior, Fortunato de Bortoli, Scalcon, Éverton Luiz, Vidal, Ribas Antonio, Diesel, Francielli, Pagnoncelli Junior, Fortunato de Bortoli, Oliveira, Marisa de Cacia, Trezzi, Michelangelo Muzell   +7 more
core   +1 more source

Yeast growth selection system for the identification of cell-active inhibitors of [beta]-secretase [PDF]

, 2004
The production and deposition of the cytotoxic Aβ peptide is a central event in the pathogenesis of Alzheimer’s disease (AD). Aβ is excised from the amyloid precursor protein (APP) through sequential actions of the β-secretase, which cleaves at the ...
Middendorp, Oliver M.
core   +1 more source

Control of common waterhemp with S-metolachlor plus fomesafen and competitiveness of protox-resistant common waterhemp [PDF]

Master of ScienceDepartment of AgronomyKassim Al-KhatibField experiments were conducted near Manhattan, KS in 2005 and 2006 and Sabetha, KS in 2005 to determine the efficacy of S-metolachlor tank mixed with fomesafen on common waterhemp in soybean ...
Duff, Michael Graham
core  

Assessment of the Inhibitory Potential of Flavonoids on the Internalin A Protein of Listeria monocytogenes Through Molecular Docking

Orbital: The Electronic Journal of Chemistry
Listeria monocytogenes is an intracellular pathogen capable of colonizing its hosts through virulence factors, with the Internalin A (InlA) protein being particularly notable.
Cristian Sillagana Verdezoto
doaj   +1 more source

Local de absorção de fomesafen como mecanismo de resistência em biótipo de Euphorbia heterophylla resistente aos inibidores da PROTOX

, 2017
Três experimentos foram realizados para verificar se o local de aplicação de fomesafen, folhas ou solo, afeta a eficácia desse herbicida em biótipos de E.
Gustmann, M.S., Franchin, E., Vidal, R.A., Silva, R.P., Trezzi, M.M., Kruse, N.D.   +5 more
core  

Effective use of corrosion inhibitors in highway structures [PDF]

, 2007
Paper presented at the IABSE Symposium 'Improving Infrastructure Worldwide- brining people closer', Weimar, Germany, September 19-21, 2007The corrosion of European concrete highway structures leads to traffic disruption, significant expenditure on ...
Richardson, Mark G., McNally, Ciaran
core   +1 more source