Results 81 to 90 of about 610,579 (177)

In silico prediction of octahydro-1H-indole-2-carboxamide derivatives as novel acetylcholinesterase inhibitors: a comprehensive computational study

Egyptian Journal of Medical Human Genetics
Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterised by cognitive decline and memory loss. Acetylcholinesterase (AChE)inhibition remains a crucial therapeutic strategy for AD treatment.
Satyavani Meesala, Swathi Nageswara, Rajkiran Kolakota, Muni Kumar Dokka, Mumpi Giri, Priyadarsini Bada, Vidya Sagar Jerra   +6 more
doaj   +1 more source

Multi-Target In Silico Evaluation of New 2-Pyrazolines as Antimicrobial Agents

Chemistry Proceedings
The world today is being ravaged by the emergence and re-emergence of microbial infections caused by antimicrobial-resistant strains, brought about primarily by the frequent and perhaps unnecessary use of antimicrobial agents.
Zukhruf Salami, Asmau Hamza, Abdullahi Idris, Yusuf Jimoh   +3 more
doaj   +1 more source

The cost and availability of rare earth-based corrosion inhibitors

, 2014
Rare earths have been studied extensively as corrosion inhibitors for a range of metals. However, there is little information about the viability of the rare earths as inhibitors from the perspective of price and availability.
Mol, J.M.C., Cole, IS, I.S. Cole, Hughes, Anthony E., J.M.C. Mol, Hughes, AE, Cole, Ivan, A.E. Hughes, Mol, JMC   +8 more
core   +1 more source

Cysteine proteinase inhibitors: purification and gene isolation [PDF]

, 1989
Genetic engineering has produced a transgenic insect- resistant plant which produces a serine protease inhibitor (Hilder et al., 1987). More insects can be targetted if a plant can be made to produce thiol protease inhibitors.
Fones, Angela Mei Ling
core  

Correlation of Matrix Metalloproteinases and Tissue Inhibitors of Matrix Metalloproteinase Expression in Ileal Carcinoids, Lymph Nodes and Liver Metastasis with Prognosis and Survival [PDF]

, 2009
Purpose: Ileal carcinoids are gut epithelial tumors originating from serotonin-containing enterochromaffin (EC) cells. Therapeutic options for effectively inhibiting the growth and spread of metastatic carcinoids are still limited.
Braun, Thomas, Besig, Sophie, Baur, Dorothee M., Prinz, Christian, Rad, Roland, Hoefler, Heinz, Höfler, Heinz, Voland, Petra, Perren, Aurel, Langer, Rupert, Voland, P;Besig, S;Rad, R;Braun, T;Baur, DM;Perren, A;Langer, R;Höfler, H;Prinz, C, Voland, Petra;Besig, Sophie;Rad, Roland;Braun, Thomas;Baur, Dorothee M.;Perren, Aurel;Langer, Rupert;Höfler, Heinz;Prinz, Christian   +11 more
core   +2 more sources

In Silico Analysis of Bioactive Compounds from Imperata cylindrica as Potential EGFR Inhibitors in Cervical Cancer

Biology, Medicine & Natural Product Chemistry
Cervical cancer remains a major cause of death in women globally. Conventional treatments often result in toxicity and resistance, prompting interest in natural alternatives.
Muhammad Farid, Hanin Fitri Aqilanisa, Jihan Aqila Najwa Ulayya, Gylda Shareefa Carent Nissiara, Murni Ramadhani, Ardestya Rastrani   +5 more
doaj   +1 more source

Studies on a-amylase inhibitors from seeds of sorghum bicolor [PDF]

, 1991
Six inhibitors (Slal, SIa2, SIa3, SIa4, SIa5 and SIa6) of a-amylase from mammalian, insect, bacterial and fungal sources were purified from seeds of Sorghum bicolor (L) Moench by saline extraction, precipitation with ammonium sulphate, affinity ...
Junior, Carlos Bloch
core  

Aplicações seqüenciais de flumicloracpentil para o controle de Euphorbia heterophylla na cultura da soja = Sequential application of flumicloracpentil for Euphorbia heterophylla control in soybeans

Acta Scientiarum. Agronomy, 2006
Euphorbia heterophylla destacase como a principal planta daninha na cultura da soja no Estado do Paraná, não só pela sua disseminação, mas também pela natural dificuldade de controle e pela ocorrência de biótipos que apresentam resistência.
Rubem Silvério de Oliveira Jr, Jamil Constantin, Roberto Toledo, Luciano Hiroyuki Kajihara, Ângelo Stasieviski, Paulo Humberto Pagliari, João Guilherme Zanetti de Arantes, Sidnei Douglas Cavalieri, Diego Gonçalves Alonso, Ana Carolina Roso   +9 more
doaj  

Inhibitors of PCSK9 enzyme as a drug for hypercholesterolemia

, 2020
New class of drugs, fully humanized monoclonal antibodies, evolocumab and alirocumab, work as PCSK9 inhibitors. Evolocumab and alirocumab bind free plasma PCSK9 and lead to its degradation, as a result, less free PCSK9 is available in the plasma to bind ...
Nashashibi, Mary
core  

The predicted toxicity for 10d, 16, 6d, and 10a using: (a) ProTox-II and (b) Pred-hERG software.

, 2023
The predicted toxicity for 10d, 16, 6d, and 10a using: (a) ProTox-II and (b) Pred-hERG software.
Ghaidaa H. Alfaifi (14701304), Magda H. Abdellattif (9902643), Thoraya A. Farghaly (7846112)   +2 more
core   +1 more source