Results 11 to 20 of about 9,211 (166)

Assessing the impact of preventative measures to limit the spread of Toxoplasma gondii in wild carnivores of Madagascar. [PDF]

Conserv Biol
Abstract Novel multihost pathogens can threaten endangered wildlife species, as well as humans and domestic animals. The zoonotic protozoan parasite Toxoplasma gondii is transmitted by members of Felidae and can infect a large number of animal species, including humans.
Rasambainarivo FT, Randrianarisoa S, Rasolofoniaina OA, Rice BL, Metcalf CJE.   +4 more
europepmc   +2 more sources

Fatal disseminated toxoplasmosis in a feline immunodeficiency virus-positive cat receiving oclacitinib for feline atopic skin syndrome. [PDF]

Vet Dermatol, 2022
Toxoplasma gondii is a ubiquitous protozoan, for which felids are the definitive host. Immunocompromised individuals are susceptible to recrudescent toxoplasmosis. This case describes a 6‐year‐old, feline immunodeficiency virus‐positive domestic short hair cat with feline atopic skin syndrome, that developed fatal toxoplasmosis after treatment with ...
Moore A, Burrows AK, Malik R, Ghubash RM, Last RD, Remaj B.   +5 more
europepmc   +2 more sources

Cell culture‐derived extracellular vesicles: Considerations for reporting cell culturing parameters

Journal of Extracellular Biology, Volume 2, Issue 10, October 2023., 2023
Abstract Cell culture‐conditioned medium (CCM) is a valuable source of extracellular vesicles (EVs) for basic scientific, therapeutic and diagnostic applications. Cell culturing parameters affect the biochemical composition, release and possibly the function of CCM‐derived EVs (CCM‐EV).
Faezeh Shekari, Faisal J. Alibhai, Hossein Baharvand, Verena Börger, Stefania Bruno, Owen Davies, Bernd Giebel, Mario Gimona, Ghasem Hosseini Salekdeh, Lorena Martin‐Jaular, Suresh Mathivanan, Inge Nelissen, Esther Nolte‐’t Hoen, Lorraine O'Driscoll, Francesca Perut, Stefano Pluchino, Gabriella Pocsfalvi, Carlos Salomon, Carolina Soekmadji, Simon Staubach, Ana Claudia Torrecilhas, Ganesh Vilas Shelke, Tobias Tertel, Dandan Zhu, Clotilde Théry, Kenneth Witwer, Rienk Nieuwland   +26 more
wiley   +1 more source

Guidelines for the purification and characterization of extracellular vesicles of parasites

Journal of Extracellular Biology, Volume 2, Issue 10, October 2023., 2023
Abstract Parasites are responsible for the most neglected tropical diseases, affecting over a billion people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible for several millions of deaths. Research on extracellular vesicles (EVs) has increased in recent years and demonstrated that EVs shed by pathogenic parasites ...
Carmen Fernandez‐Becerra, Patrícia Xander, Daniel Alfandari, George Dong, Iris Aparici‐Herraiz, Irit Rosenhek‐Goldian, Mehrdad Shokouhy, Melisa Gualdron‐Lopez, Nicholy Lozano, Nuria Cortes‐Serra, Paula Abou Karam, Paula Meneghetti, Rafael Pedro Madeira, Ziv Porat, Rodrigo Pedro Soares, Adriana Oliveira Costa, Sima Rafati, Anabela‐Cordeiro da Silva, Nuno Santarém, Christopher Fernandez‐Prada, Marcel I. Ramirez, Dolores Bernal, Antonio Marcilla, Vera Lucia Pereira‐Chioccola, Lysangela Ronalte Alves, Hernando Del Portillo, Neta Regev‐Rudzki, Igor Correia de Almeida, Sergio Schenkman, Martin Olivier, Ana Claudia Torrecilhas   +30 more
wiley   +1 more source

Characterisation of extracellular vesicles isolated from hydatid cyst fluid and evaluation of immunomodulatory effects on human monocytes

Journal of Cellular and Molecular Medicine, Volume 27, Issue 17, Page 2614-2625, September 2023., 2023
Abstract Hydatidosis is a disease caused by the larval stage of Echinococcus granulosus, which involves several organs of intermediate hosts. Evidence suggests a communication between hydatid cyst (HC) and hosts via extracellular vesicles. However, a little is known about the communication between EVs derived from HC fluid (HCF) and host cells.
Mojdeh Khosravi, Hanieh Mohammad Rahimi, Abdoreza Nazari, Kaveh Baghaei, Hamid Asadzadeh Aghdaei, Shabnam Shahrokh, Meysam Sharifdini, Ana Claudia Torrecilhas, Fatemeh Mehryab, Hamed Mirjalali, Faezeh Shekari, Mohammad Reza Zali   +11 more
wiley   +1 more source

Extracellular Vesicles in Trypanosoma cruzi Infection: Immunomodulatory Effects and Future Perspectives as Potential Control Tools against Chagas Disease

Journal of Immunology Research, Volume 2022, Issue 1, 2022., 2022
Chagas disease, caused by the protozoa parasite Trypanosoma cruzi, is a neglected tropical disease and a major public health problem affecting more than 6 million people worldwide. Many challenges remain in the quest to control Chagas disease: the diagnosis presents several limitations and the two available treatments cause several side effects ...
Nuria Cortes-Serra, Melisa Gualdron-Lopez, Maria-Jesus Pinazo, Ana Claudia Torrecilhas, Carmen Fernandez-Becerra, Daniele Maria-Ferreira   +5 more
wiley   +1 more source

New Biomarker in Chagas Disease: Extracellular Vesicles Isolated from Peripheral Blood in Chronic Chagas Disease Patients Modulate the Human Immune Response

Journal of Immunology Research, Volume 2021, Issue 1, 2021., 2021
Chagas disease, a neglected tropical disease (NTD) caused by the flagellated protozoan Trypanosoma cruzi (T. cruzi), is a major public health problem. It was initially restricted to Latin America, but it is now expanding globally. Host and pathogen interactions are crucial in the establishment of disease, and since 1970, it has been known that ...
Rafael Pedro Madeira, Lavínia Maria Dal’Mas Romera, Paula de Cássia Buck, Charles Mady, Barbara Maria Ianni, Ana Claudia Torrecilhas, Luiz Felipe Domingues Passero   +6 more
wiley   +1 more source

Long‐Term In Vitro Passaging Had a Negligible Effect on Extracellular Vesicles Released by Leishmania amazonensis and Induced Protective Immune Response in BALB/c Mice

Journal of Immunology Research, Volume 2021, Issue 1, 2021., 2021
Depending on Leishmania species and the presence/absence of virulence factors, Leishmania extracellular vesicles (EVs) can differently stimulate host immune cells. This work is aimed at characterizing and evaluating the protective role of EVs released by Leishmania amazonensis promastigotes under different maintenance conditions.
Talita Vieira Dupin, Natasha Ferraz de Campos Reis, Elizabeth Cristina Perez, Rodrigo Pedro Soares, Ana Claudia Torrecilhas, Patricia Xander, Roberta Antonia Diotti   +6 more
wiley   +1 more source

Alterações hematológicas em coelhos infectados experimentalmente pelo Trypanosoma evansi Hematological changes in rabbits experimentally infected by Trypanosoma evansi

Ciência Rural, 2008
O objetivo deste trabalho foi avaliar as alterações hematológicas em coelhos infectados experimentalmente pelo Trypanosoma evansi. Foram utilizados seis coelhos, machos, divididos em dois grupos, sendo o grupo controle composto de animais não infectados ...
Aleksandro Schafer da Silva, Marcio Machado Costa, Sonia Terezinha dos Anjos Lopes, Silvia Gonzalez Monteiro   +3 more
doaj   +1 more source

Inserção de DNA de Trypanosoma cruzi no genoma de célula hospedeira de mamífero por meio de infecção

Revista da Sociedade Brasileira de Medicina Tropical, 1991
Observamos a cromatina deformas amastigotas de T. cruzi associada a cromossomos de macrófagos metafásicos obtidos em diversos períodos da infecção aguda.
Antonio R.L. Teixeira, Zulmira Lacava, Jaime M. Santana, Helena Luna   +3 more
doaj   +3 more sources