Medicines for Malaria Venture Pandemic Box In Vitro Screening Identifies Compounds Highly Active against the Tachyzoite Stage of Toxoplasma gondii [PDF]
Toxoplasmosis is a disease that causes high mortality in immunocompromised individuals, such as AIDS patients, and sequelae in congenitally infected newborns.
Mike dos Santos +5 more
doaj +2 more sources
Depending on Leishmania species and the presence/absence of virulence factors, Leishmania extracellular vesicles (EVs) can differently stimulate host immune cells. This work is aimed at characterizing and evaluating the protective role of EVs released by
Talita Vieira Dupin +5 more
doaj +2 more sources
Chagas disease, caused by the protozoa parasite Trypanosoma cruzi, is a neglected tropical disease and a major public health problem affecting more than 6 million people worldwide.
Nuria Cortes-Serra +4 more
doaj +2 more sources
Advancing research on parasitic infections: Standardized extracellular vesicle guideline. [PDF]
Journal of Extracellular Vesicles, Volume 13, Issue 12, December 2024.
Fernandez-Becerra C +3 more
europepmc +2 more sources
New Biomarker in Chagas Disease: Extracellular Vesicles Isolated from Peripheral Blood in Chronic Chagas Disease Patients Modulate the Human Immune Response. [PDF]
Chagas disease, a neglected tropical disease (NTD) caused by the flagellated protozoan Trypanosoma cruzi (T. cruzi), is a major public health problem. It was initially restricted to Latin America, but it is now expanding globally. Host and pathogen interactions are crucial in the establishment of disease, and since 1970, it has been known that ...
Madeira RP +5 more
europepmc +2 more sources
Connecting through ISEV's developing social media landscape. [PDF]
Journal of Extracellular Vesicles, Volume 13, Issue 7, July 2024.
Driedonks TAP +6 more
europepmc +2 more sources
Five Years of EVClub-From Journal Club to Worldwide Discussion Hub. [PDF]
Journal of Extracellular Vesicles, Volume 14, Issue 12, December 2025.
Alique M +3 more
europepmc +2 more sources
Almost all cells and organisms release membrane structures containing proteins, lipids, and nucleic acids called extracellular vesicles (EVs), which have a wide range of functions concerning intercellular communication and signaling events. Recently, the
João Henrique Campos +5 more
doaj +2 more sources
Antiproliferative and Morphological Analysis Triggered by Drugs Contained in the Medicines for Malaria Venture COVID-Box Against Toxoplasma gondii Tachyzoites [PDF]
Toxoplasma gondii is a protozoan, and the etiologic agent of toxoplasmosis, a disease that causes high mortality in immunocompromised individuals and newborns.
Andréia Luiza Oliveira Costa +5 more
doaj +2 more sources
Characterisation of extracellular vesicles isolated from hydatid cyst fluid and evaluation of immunomodulatory effects on human monocytes. [PDF]
Abstract Hydatidosis is a disease caused by the larval stage of Echinococcus granulosus, which involves several organs of intermediate hosts. Evidence suggests a communication between hydatid cyst (HC) and hosts via extracellular vesicles. However, a little is known about the communication between EVs derived from HC fluid (HCF) and host cells.
Khosravi M +11 more
europepmc +2 more sources

