Results 1 to 10 of about 867 (112)

Medicines for Malaria Venture Pandemic Box In Vitro Screening Identifies Compounds Highly Active against the Tachyzoite Stage of Toxoplasma gondii [PDF]

open access: yesTropical Medicine and Infectious Disease, 2023
Toxoplasmosis is a disease that causes high mortality in immunocompromised individuals, such as AIDS patients, and sequelae in congenitally infected newborns.
Mike dos Santos   +5 more
doaj   +2 more sources

Long-Term In Vitro Passaging Had a Negligible Effect on Extracellular Vesicles Released by Leishmania amazonensis and Induced Protective Immune Response in BALB/c Mice

open access: yesJournal of Immunology Research, 2021
Depending on Leishmania species and the presence/absence of virulence factors, Leishmania extracellular vesicles (EVs) can differently stimulate host immune cells. This work is aimed at characterizing and evaluating the protective role of EVs released by
Talita Vieira Dupin   +5 more
doaj   +2 more sources

Extracellular Vesicles in Trypanosoma cruzi Infection: Immunomodulatory Effects and Future Perspectives as Potential Control Tools against Chagas Disease

open access: yesJournal of Immunology Research, 2022
Chagas disease, caused by the protozoa parasite Trypanosoma cruzi, is a neglected tropical disease and a major public health problem affecting more than 6 million people worldwide.
Nuria Cortes-Serra   +4 more
doaj   +2 more sources

Advancing research on parasitic infections: Standardized extracellular vesicle guideline. [PDF]

open access: yesJ Extracell Vesicles
Journal of Extracellular Vesicles, Volume 13, Issue 12, December 2024.
Fernandez-Becerra C   +3 more
europepmc   +2 more sources

New Biomarker in Chagas Disease: Extracellular Vesicles Isolated from Peripheral Blood in Chronic Chagas Disease Patients Modulate the Human Immune Response. [PDF]

open access: yesJ Immunol Res, 2021
Chagas disease, a neglected tropical disease (NTD) caused by the flagellated protozoan Trypanosoma cruzi (T. cruzi), is a major public health problem. It was initially restricted to Latin America, but it is now expanding globally. Host and pathogen interactions are crucial in the establishment of disease, and since 1970, it has been known that ...
Madeira RP   +5 more
europepmc   +2 more sources

Connecting through ISEV's developing social media landscape. [PDF]

open access: yesJ Extracell Vesicles
Journal of Extracellular Vesicles, Volume 13, Issue 7, July 2024.
Driedonks TAP   +6 more
europepmc   +2 more sources

Five Years of EVClub-From Journal Club to Worldwide Discussion Hub. [PDF]

open access: yesJ Extracell Vesicles
Journal of Extracellular Vesicles, Volume 14, Issue 12, December 2025.
Alique M   +3 more
europepmc   +2 more sources

Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases

open access: yesJournal of Immunology Research, 2015
Almost all cells and organisms release membrane structures containing proteins, lipids, and nucleic acids called extracellular vesicles (EVs), which have a wide range of functions concerning intercellular communication and signaling events. Recently, the
João Henrique Campos   +5 more
doaj   +2 more sources

Antiproliferative and Morphological Analysis Triggered by Drugs Contained in the Medicines for Malaria Venture COVID-Box Against Toxoplasma gondii Tachyzoites [PDF]

open access: yesMicroorganisms
Toxoplasma gondii is a protozoan, and the etiologic agent of toxoplasmosis, a disease that causes high mortality in immunocompromised individuals and newborns.
Andréia Luiza Oliveira Costa   +5 more
doaj   +2 more sources

Characterisation of extracellular vesicles isolated from hydatid cyst fluid and evaluation of immunomodulatory effects on human monocytes. [PDF]

open access: yesJ Cell Mol Med, 2023
Abstract Hydatidosis is a disease caused by the larval stage of Echinococcus granulosus, which involves several organs of intermediate hosts. Evidence suggests a communication between hydatid cyst (HC) and hosts via extracellular vesicles. However, a little is known about the communication between EVs derived from HC fluid (HCF) and host cells.
Khosravi M   +11 more
europepmc   +2 more sources

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