Results 241 to 250 of about 5,697,775 (262)
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Large‐scale survey for potentially targetable indels in bacterial and protozoan proteins
Proteins: Structure, Function, and Bioinformatics, 2005AbstractOur previous results demonstrated that some essential, housekeeping proteins from pathogenic microorganisms may contain sizable insertions–deletions in their sequences (compared to close human homologs) that can be responsible for unexpected virulence properties.
A. Cherkasov +3 more
semanticscholar +3 more sources
The role of ATP-binding cassette (ABC) proteins in protozoan parasites.
Molecular and Biochemical Parasitology, 2009The ATP-binding cassette (ABC) superfamily is one of the largest protein families with representatives in all kingdoms of life. Members of this superfamily are involved in a wide variety of transport processes with substrates ranging from small ions to relatively large polypeptides and polysaccharides, but also in cellular processes such as DNA repair,
V. Sauvage +3 more
semanticscholar +3 more sources
Glycosylation of proteins in the protozoan Euglena gracilis
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1985Abstract 1. 1. The main dolichol-P-P-bound oligosaccharide present in Euglena gracilis cells incubated with [U- 14 C]glucose was found to migrate on paper chromatography as a Glc 3 Man 9 GlcNAc 2 standard and to contain glucose, mannose and N- acetylglucosamine residues. 2. 2.
L. Canal, A. Parodi
semanticscholar +2 more sources
Using Protozoan Surface Proteins for Effective Oral Vaccination
Trends in Parasitology, 2020The Global Vaccine Action Plan of the World Health Organization (WHO) calls for nonsyringe delivery mechanisms, thermostable vaccines, and new bioprocessing technologies as priority research areas. Here we discuss the use of protozoan surface proteins to develop a safe, stable, and efficient versatile oral vaccine platform.
Lucía Lara, Rupil +2 more
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Protozoan protein tyrosine phosphatases
International Journal for Parasitology, 2008The aim of this review is to provide a synthesis of the published experimental data on protein tyrosine phosphatases from parasitic protozoa, in silico analysis based on the availability of completed genomes and to place available data for individual phosphatases from different unicellular parasites into the comparative and evolutionary context.
Alexandra V, Andreeva +1 more
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Pathogenic role of mitogen activated protein kinases in protozoan parasites
Biochimie, 2022Protozoan parasites with complex life cycles have high mortality rates affecting billions of human lives. Available anti-parasitic drugs are inadequate due to variable efficacy, toxicity, poor patient compliance and drug-resistance. Hence, there is an urgent need for the development of safer and better chemotherapeutics.
Pavneet, Kaur, Neena, Goyal
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Protein and RNA inhibitors and protozoan habituation
Psychopharmacologia, 1970A variety of protein and RNA inhibitors were tested on habituation learning in the protozoan Spirostomum. Inhibition of protein synthesis up to values of 95% had no effect upon habituation, and RNA inhibition up to 89% by 5-fluorouracil had only slight effects upon it. Large amounts of protein and RNA synthesis are not necessary for habituation.
F T, Gardner, P B, Applewhite
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Characterization of Trichomonas vaginalis virus proteins in the pathogenic protozoan T. vaginalis
Archives of Virology, 1998The 4.6-kb double-stranded (ds) RNA of Trichomonas vaginalis virus (TVV)-T1 has been shown to encode two overlapping genes, cap and pol. In this study, a serum for specifically detecting viral cap gene product was raised against a recombinant protein, and sera for specifically detecting pol gene product were raised against synthetic oligopeptides. A 75-
H.-W. Liu, Y. Chu, J. Tai
semanticscholar +3 more sources
Dna-Protein Interactions at Telomeres in Ciliated Protozoans
Advances in Molecular and Cell Biology, 1988Publisher Summary This chapter discusses the DNA–protein complexes found at telomeres in the macronuclei of ciliated protozoans, with special attention given to studies in Oxytricha (a hypotrichous ciliate) and Tetrahymena (a holotrichous ciliate). The structure of telomeres has been largely elucidated by studies on macronuclear DNA from ciliated
D GOTTSCHLING, V ZAKIAN
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Protein synthesis and cell division in a pyrimidine-starved protozoan
Experimental Cell Research, 1960Abstract In media complete save for uracil, T. pyriformis continues to make protein, divide, and form normal cells, although its net RNA content does not increase. Uracil-starved cells rapidly regain their original RNA level when uracil is restored.
S, LEDERBERG, D, MAZIA
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