Results 81 to 90 of about 42,476 (197)

Murine T Cell‐Dependent Response Affects Leishmania amazonensis Amastigote Survival and Virulence

Cell Biology International, Volume 50, Issue 8, August 2026.
ABSTRACT Our group has previously described the infection course of Leishmania amazonensis in BALB/c and BALB/cnu/nu mice, which have distinct T‐cell dependent responses. In this study, lesion‐derived amastigotes exhibited differential protein expression in a host‐dependent manner.
Gustavo Henrique Corrêa Soares, Gustavo Rolim Barbosa, Beatriz Simonsen Stolf   +2 more
wiley   +1 more source

Selenium‐Containing 1,4‐Naphthoquinone Derivatives Trigger Reactive Oxygen Species and Apoptosis in Triple‐Negative Breast Cancer Cells

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Cancer ranks as a leading cause of death worldwide, demanding new affordable therapies. Nature offers a diverse array of bioactive scaffolds, including 1,4‐naphthoquinone, which serves as a precursor for numerous natural and synthetic compounds with potent antitumor properties.
Eduardo Angulo‐Elizari, Asif Raza, Hannah Johnson, Nuria Martínez‐Sáez, Ignacio Encío, Arun K. Sharma, Carmen Sanmartín, Daniel Plano   +7 more
wiley   +1 more source

The past, present and future of fluorescent protein tags in anaerobic protozoan parasites

Parasitology, 2015
SUMMARYThe world health organization currently recognizes diarrhoeal diseases as a significant cause of death in children globally. Protozoan parasites such asGiardiaandEntamoebathat thrive in the oxygen-deprived environment of the human gut are common etiological agents of diarrhoea.
Victoria, Morin-Adeline, Jan, Šlapeta
openaire   +2 more sources

Investigation and Comparison of Leishmania major Promastigote and Amastigote Protein Content by Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis

پزشکی بالینی ابن سینا, 2013
Introduction & Objective: Leishmania is a protozoan of the trypanosomatidae family. This protozoan has two stages in its life cycle, promastigote form in sand flies and amastigote form in macrophage of mammalian hosts.
Simindokht Soleimanifard, Reza Arjmand, Seyyed Hosein Hejazi   +2 more
doaj  

Environment and Host Genetics Drive Infection Outcomes in a Butterfly Host, but Do Not Interact With Each Other

Ecology and Evolution, Volume 16, Issue 8, August 2026.
This study examined how host genetics and larval food plant environment influence parasite infection outcomes in monarch butterflies (Danaus plexippus) infected with the protozoan Ophryocystis elektroscirrha. We tested for genotype × environment interactions on infection status, infection burden, lifespan, and wing size.
Ania A. Majewska, Grace Chlebove, Jacobus C. de Roode   +2 more
wiley   +1 more source

Novel Features of a PIWI-Like Protein Homolog in the Parasitic Protozoan Leishmania

PLoS ONE, 2012
In contrast to nearly all eukaryotes, the Old World Leishmania species L. infantum and L. major lack the bona fide RNAi machinery genes. Interestingly, both Leishmania genomes code for an atypical Argonaute-like protein that possesses a PIWI domain but lacks the PAZ domain found in Argonautes from RNAi proficient organisms.
Prasad K Padmanabhan, Carole Dumas, Mukesh Samant, Annie Rochette, Martin J Simard, Barbara Papadopoulou   +5 more
openaire   +4 more sources

Energy Allocation Explains How Protozoan Phenotypic Traits Change in Response to Temperature and Resource Supply

Ecology and Evolution, Volume 16, Issue 8, August 2026.
When cultures of the microorganism Tetrahymena pyriformis are transferred to environments with different temperature and resource levels, the phenotypic traits of the microorganisms—including cell size, metabolic rate, and movement speed—change.
Andrea Perna, Enrico S. Rivoli, Julia Reiss, Daniel M. Perkins   +3 more
wiley   +1 more source

Insights Into the Biological Mechanisms and Multifunctional Health Benefits of Morelloflavone

eFood, Volume 7, Issue 4, August 2026.
Morelloflavone (MF), a biflavonoid from Garcinia and related species, exhibits broad human health benefits through antioxidant, anti‐inflammatory, anticancer, and metabolic regulatory effects. This review highlights its molecular mechanisms, biosynthesis, and emerging roles in chronic disease prevention, emphasizing systems biology and machine learning
Yi Liu, Ziyong Mao, Jesus Simal‐Gandara, Zi Chen, Hui Cao   +4 more
wiley   +1 more source

Protein synthesis in mitochondria isolated from the trypanosomatid protozoan Crithidia fasciculata [PDF]

FEBS Letters, 1998
Evidence presented over the years in support of mitochondrial translation in trypanosomes, based largely on studies using differential inhibitors such as cycloheximide and chloramphenicol, remains controversial. I have studied endogenous mRNA‐dependent translation in a mitochondrial fraction isolated from the trypanosomatid protozoan Crithidia ...
openaire   +2 more sources

A Mechanistic Review of Environmental Stressor to Decode Their Effect on Congenital Malformations: A Developmental Toxicity

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Environmental toxicants may disrupt developmental pathways via strong molecular docking interactions with hub FGF proteins (FGF9 and FGF4) like dibenzo‐p‐dioxin (−7.2 kcal/mol) at the ASN146 residue of FGF9, driving congenital malformations as revealed by PPI networks and toxicity profiling.
Adarsh Kumar Shukla, Rashmi Mahajan, Anuj Kumar Tyagi, Kamendra Swaroop   +3 more
wiley   +1 more source