Results 71 to 80 of about 4,006,829 (297)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Opioid prescriptions following behavioral health training among primary care providers

BMC Medical Education
Background Overdose deaths due to opioids are a major concern in the United States. Physicians often report inadequate training in chronic pain and substance use disorder management. Here, we evaluate whether a specialized program, the Train New Trainers
Shutong Huo, Tim A. Bruckner, Abhery Das, Glen L. Xiong, David Marcovitz, Ariel B. Neikrug, Robert McCarron   +6 more
doaj   +1 more source

Private training providers in Scotland [PDF]

Journal of Vocational Education & Training, 2002
Abstract Reliable information on the private provision of training is scarce. This article, based on analysis of Scottish Qualifications Authority (SQA) and City and Guilds (C & G) data sets for the period 1996-97 to 1998-99, provides an estimate of around 300 private training providers (PTPs) operating in Scotland.
Mike Osborne, Eileen Turner
openaire   +1 more source

Patient-Provider Communication Training Models for Interactive Speech Devices

, 2021
Patient-provider communication plays a major role in healthcare with its main goal being to improve the patient’s health and build a trustworthy relationship between the patient and the doctor. Provider’s efficiency and effectiveness in communication can
Kirk Roberts, Roberts, Kirk, Muhammad Amith, Ngantcha, Patricia, Amith, Muhammad, Tao, Cui, Cui Tao, Patricia Ngantcha   +7 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Understanding mechanisms of multi-level implementation strategies for autism interventions in a randomized trial across service systems

Implementation Science
Background Understanding the effectiveness of implementation strategies to support uptake of evidence-based interventions (EBIs) requires examining activation of mechanisms targeted by implementation strategies.
Aubyn C. Stahmer, Anna S. Lau, Scott Roesch, Elizabeth Rangel, Gregory A. Aarons, Lauren Brookman-Frazee   +5 more
doaj   +1 more source

SPECIFIC TRAINING FOR NUCLEAR SERVICE PROVIDERS

Journal of Energy Technology
The aim of the specific training courses for nuclear service providers is to ensure that capable personnel as a paramount objective not only for nuclear power plants, research facilities, institutes and regulatory bodies, but also for industries that provide products and services in support of the maintenance and operation of existing plants, as well ...
Srebotnik, Rebeka, Lešnjak, Andrej
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

PURSUIT Protocol: Development of a Novel Approach to Managing Youth Physical and Mental Health in Schools

Children
Background/Objectives: Physical and mental health symptoms commonly affecting children are often under-addressed given the limited availability of pediatric behavioral healthcare.
Thea Senger-Carpenter, Jocelyn Zuckerman, Audrey Searles, Cara Poland, Crystal L. Cederna, Sarah Nelson, Mallet R. Reid, Kelly Theaker, Steven J. Pierce, Angela Chia-Chen Chen, Natoshia R. Cunningham   +10 more
doaj   +1 more source