Results 91 to 100 of about 1,761,957 (311)

Account Ledger, Province (1 of 2)

open access: yes
Common Expense Book (1860-11-10-1866-09-03); Province Taxes (1873-1895); Masses (1878-03-28--1901-06-30) and Missions (1893-05-31-1892-05-31)**Former finding aid locations: 119_91_1; 418*

core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Further evidence of community education effects on fertility in sub-Saharan Africa

open access: yesDemographic Research, 2012
BACKGROUND Earlier investigations have shown that a woman's chance of having a child, or various proximate determinants of her fertility, are influenced by the socioeconomic resources in the community in which she lives, net of her own resources ...
Øystein Kravdal
doaj  

Transformation of cultural life in the conditions of social space of the province at the turn of the 1950-ies – 1960-ies

open access: yesВестник Самарского университета: История, педагогика, филология
This article explores the characteristics of cultural development in the provinces during the 1950-ies and 1960-ies of the XX century within the context of everyday life in the Soviet Union.
O. D. Popova, M. O. Maslovsky
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Charles Stonestreet, S.J. - Missouri Province (58 of 82)

open access: yes
Contains ALS to Stonestreet from: Bp James VandeVelde of Natchez asking personnel loan for Cathedral clock repair 1/1/1855; Murphy on misc. from Missouri Province 2/9/1855, on Fr. Force 8/6/1855, on clergy needs in Chicago 10/13/1855; a Fr.

core  

Assessment of the prospects of the Dzhagdy-Selemdzinskaya gold-bearing metallogenic zone of Priamurskaya province

open access: yesИзвестия высших учебных заведений: Геология и разведка, 2015
Dzhagdy-Selemdzinskaya metallogemc zone is shown to be the one of the most productive gold-bearing zones in Priamurskaya province. The placer and ore deposits mined in the area are estimated to be about 350 t of gold, including 293,811 of placer and 57 ...
V. A. Stepanov, A. V. Melnikov
doaj   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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