Results 111 to 120 of about 2,058,339 (305)
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Litterae Annuae, Maryland Province (3 of 6)
Contains AMs L.A. Maryland Province 1847; ALS letter from James A. Ward, SJ re Georgetown College, 2/13/1848; AMs account of spiritual duties for 1847 at Holy Trinity, Georgetown; ALS L.A. Alexandria 2/23/1848; AMs L.A. Frederick Novitiate 1847; ALS L.A.
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Background. Nowadays in searching ideological foundations of society and ap-peals in this regard to Soviet ideology, the study of the party vocabulary of the of the CPSU fanile stage history is of undoubted scientific interest and is an urgent topic that
Z.M. Kobozeva, P.S. Kabytov
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Litterae Annuae, Maryland Province (4 of 6)
Contains AMs L.A. St. Mary's Boston 1871; ALS L.A. Gonzaga College 1871; AMs L.A. St. Joseph's of Talbot County, MD 1871; AMs L.A. Holy Cross College, Worcester for 1868-71; AMs L.A. Holy Trinity (German), Boston 1868-76; AMs L.A. Boston College 1868-70;
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Index to the Journals and Sessional Papers of the Legislative Assembly of the Province of Ontario. There are six volumes: 1867-1888; 1899-1900; 1901-1912; 1913-1920; 1921-1924; and 1925-1927.
Legislative Assembly of the Province of Ontario
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Contains TYP will of Isidore Daubrese SJ; ALS corresp from J.H. Richards SJ 10/13/1888 re Georgetown Law and Medical Schools (need for new building for former, questions of Catholic doctrine and medical teaching re latter); corresp re proposal to ...
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source

