Results 101 to 110 of about 2,058,339 (305)
Geo Bogza și provincia ca aventură – note despre O sută șaptezeci și cinci de minute la Mizil [PDF]
This study reinterprets an inter-wars text from the prose of Romanian writer Geo Bogza – the experimental reportage One Hundred and Seventy Five Minutes in Mizil [O sută şaptezeci şi cinci de minute la Mizil], from a multiply focused perspective.
Paul Cernat
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Litterae Annuae, Maryland Province (1 of 6)
Annuae Litterae submitted by houses:Contains ALS from Peter Verhaegen, SJ to Joseph Finotti, SJ 12/20/1847 plus ALS from Ignatius Brocard, SJ to Finotti, both re Litterae Annuae; AMs L.A. Maryland Province 1845 (two copies).**Former finding aid locations:
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Charles Stonestreet, S.J. - Missouri Province (58 of 82)
Contains ALS to Stonestreet from: Bp James VandeVelde of Natchez asking personnel loan for Cathedral clock repair 1/1/1855; Murphy on misc. from Missouri Province 2/9/1855, on Fr. Force 8/6/1855, on clergy needs in Chicago 10/13/1855; a Fr.
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Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Litterae Annuae, Maryland Province (2 of 6)
AMs L.A. Maryland Province 1846 (two drafts: rough and finished); AMs L.A. St. Inigoes 1846; AMs L.A. Worcester 1846; ALS L.A. Alexandria 1846; ALS L.A. Goshenhoppen 1846; AMs L.A. Conewago 1846; AMs L.A. St. Thomas 1846; AMs L.A. St.
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