Results 61 to 70 of about 1,196,310 (302)

The Dual-Gate Lumen Model of Renal Monoamine Transport [Retraction]

open access: yesNeuropsychiatric Disease and Treatment, 2020
Hinz M, Stein A, Uncini T. Neuropsychiatr Dis Treat. 2010;6:387–392. The Editor-in-chief and Publisher of Neuropsychiatric Disease and Treatment wish to retract the published article. Following the conclusion of our investigation the
Hinz M, Stein A, Uncini T
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Warwick hip trauma study : a randomised clinical trial comparing interventions to improve outcomes in internally fixed intracapsular fractures of the proximal femur : protocol for The WHiT Study [PDF]

open access: yes, 2010
Background Controversy exists regarding the optimal treatment for patients with displaced intracapsular fractures of the proximal femur. The recognised treatment alternatives are arthroplasty and internal fixation.
Costa, Matthew L.   +15 more
core   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Comparação entre o exame clínico, com e sem separação dental, e radiográfico interproximal no diagnóstico de cárie proximal em dentes posteriores permanentes - estudo piloto [PDF]

open access: yes, 2011
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.Objetivo: Este estudo teve como objetivo avaliar os exames clínicos, sem e com separação dental, e radiográfico interproximal no diagnóstico de cárie ...
Pottmaier, Larissa Fernanda
core  

Open reduction and Internal Fixation of Displaced Proximal Humerus Fractures with AO Stainless Steel T-Plate [PDF]

open access: yes, 2014
Background: Proximal humeral fractures are considered the last unsolved fractures in orthopaedics. The treatment is controversial and various operative modalities have been reported in the literature.
Dhar SA, Hussain S, Gul MA
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes [PDF]

open access: yes, 2012
Increased renal clearance of thiamine (vitamin B1) occurs in experimental and clinical diabetes producing thiamine insufficiency mediated by impaired tubular re-uptake and linked to the development of diabetic nephropathy.
Larkin James R.   +22 more
core   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

On the Lawfulness of Grouping by Proximity [PDF]

open access: yesCognitive Psychology, 1998
The visual system groups close things together. Previous studies of grouping by proximity have failed to measure grouping strength or to assess the effect of configuration. We do both. We reanalyze data from an experiment by Kubovy and Wagemans (1995) in which they briefly presented multi-stable dot patterns that can be perceptually organized into ...
Kubovy, M.   +2 more
openaire   +3 more sources

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