Results 101 to 110 of about 45,375 (293)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Remote Sensing, 2015 Soil moisture hampers the estimation of soil variables such as clay content from remote and proximal sensing data, reducing the strength of the relevant spectral absorption features.
Fabio Castaldi +5 more
doaj +1 more source
Remote Sensing and Proximal Sensing in Ecological Monitoring
Journal of Ecological Society, 1991 The author discusses the advantages and disadvantages of satellite imagery and large &small format aerial photography. The author has developed a facility named 'Vihangam Alok' - a specifically modified aircraft with a camera and processing laboratory for collection and analysis of data.
openaire +1 more source
Phenotyping the nutritional status of crops using proximal and remote sensing techniques [PDF]
Understanding the nutritional needs of crops is crucial for ensuring their health and maximising yield. However, the capability to accurately measure relevant physical characteristics (phenotypes) of important crops in response to complex nutrient ...
Cudjoe, D.
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Handheld sensing system for data-driven irrigation management in olive orchards
Journal of Agricultural EngineeringProper water management is necessary to optimize the quantity and quality of olive oil. The advent of monitoring tools capable of providing reliable and systematic information on tree water status, and thus vegetative growth, can be advantageous for ...
Eliseo Roma +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Elements of an Integrated Phenotyping System for Monitoring Crop Status at Canopy Level
Agronomy, 2014 Great care is needed to obtain spectral data appropriate for phenotyping in a scientifically rigorous manner. This paper discusses the procedures and considerations necessary and also suggests important pre-processing and analytical steps leading to ...
Donald Rundquist +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source