Image-Based Phenotyping for Non-Destructive In Situ Rice (Oryza sativa L.) Tiller Counting Using Proximal Sensing. [PDF]
Sensors (Basel), 2022 Yamagishi Y, Kato Y, Ninomiya S, Guo W.
europepmc +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Novel folded-PCA for improved feature extraction and data reduction with hyperspectral imaging and SAR in remote sensing [PDF]
, 2014 As a widely used approach for feature extraction and data reduction, Principal Components Analysis (PCA) suffers from high computational cost, large memory requirement and low efficacy in dealing with large dimensional datasets such as Hyperspectral ...
Han, Junwei +6 more
core +2 more sources
Monitoring Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae) Infestation in Soybean by Proximal Sensing. [PDF]
Insects, 2021 Barros PPS +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Simultaneous Prediction of Wheat Yield and Grain Protein Content Using Multitask Deep Learning from Time-Series Proximal Sensing. [PDF]
Plant Phenomics, 2022 Sun Z +11 more
europepmc +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Surveying soil-borne disease development on wild rocket salad crop by proximal sensing based on high-resolution hyperspectral features. [PDF]
Sci Rep, 2022 Galieni A +5 more
europepmc +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source