Results 121 to 130 of about 45,375 (293)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Image-Based Phenotyping for Non-Destructive In Situ Rice (Oryza sativa L.) Tiller Counting Using Proximal Sensing. [PDF]

Sensors (Basel), 2022
Yamagishi Y, Kato Y, Ninomiya S, Guo W.
europepmc   +1 more source

Proximal sensing of CO2 uptake in terrestrial ecosystems [PDF]

, 2014
Linking remote sensing with carbon fluxes and vegetation biophysical parameters is critical to exploit spatial and temporal extensive information useful for validating model simulations at different scales. Proximal sensing is fundamental to quantify and
Marcolla, Barbara, Sakowska, Karolina, Gianelle, Damiano, Juszczak, R., Vescovo, Loris   +4 more
core  

Detection of the tulip breaking virus (TBV) in tulips using optical sensors

, 2009
The tulip breaking virus (TBV) causes severe economic losses for countries that export tulips such as the Netherlands. Infected plants have to be removed from the field as soon as possible.
Doorn, J., van, Baltissen, A.H.M.C., Heijden, G.W.A.M., van der, Clevers, J.G.P.W., Polder, G., Schoor, R., van der   +5 more
core   +1 more source

The potential and prospects of proximal remote sensing of arthropod pests [PDF]

, 2016
Bench-top or proximal remote sensing applications are widely used as part of quality control and machine vision systems in commercial operations. In addition, these technologies are becoming increasingly important in insect systematics and studies of ...
Nansen, Christian, Christian Nansen
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Integrating Hyperspectral, Thermal, and Ground Data with Machine Learning Algorithms Enhances the Prediction of Grapevine Yield and Berry Composition

Remote Sensing
Accurately predicting grapevine yield and quality is critical for optimising vineyard management and ensuring economic viability. Numerous studies have reported the complexity in modelling grapevine yield and quality due to variability in the canopy ...
Shaikh Yassir Yousouf Jewan, Deepak Gautam, Debbie Sparkes, Ajit Singh, Lawal Billa, Alessia Cogato, Erik Murchie, Vinay Pagay   +7 more
doaj   +1 more source

Monitoring Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae) Infestation in Soybean by Proximal Sensing. [PDF]

Insects, 2021
Barros PPS, Schutze IX, Iost Filho FH, Yamamoto PT, Fiorio PR, Demattê JAM.   +5 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source