Results 101 to 110 of about 53,118 (291)

Expression of De Novo Open Reading Frames in Natural Populations of Drosophila melanogaster

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
We show that newly‐evolved, expressed open reading frames (neORFs) identified in a set of inbred Drosophila melanogaster lines are also expressed in multiple tissues and developmental stages of pooled population samples from Europe and Africa, although differential expression of neORFs between populations is often tissue‐ or stage‐specific. ABSTRACT De
Amanda Glaser‐Schmitt   +4 more
wiley   +1 more source

Enhanced MCP-1 Release in Early Autosomal Dominant Polycystic Kidney Disease

open access: yesKidney International Reports, 2021
Introduction: Autosomal dominant polycystic kidney disease (ADPKD) causes kidney failure typically in adulthood, but the disease starts in utero. Copeptin, epidermal growth factor (EGF), and monocyte chemoattractant protein-1 (MCP-1) are associated with ...
Peter Janssens   +16 more
doaj  

The effect of elexacaftor–tezacaftor–ivacaftor on liver stiffness in children with cystic fibrosis

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Cystic fibrosis hepato‐biliary involvement (CFHBI) is a common comorbidity in patients with CF and is associated with increased morbidity and mortality. The effect of the new and highly potent CF transmembrane conductance regulator modulator therapy, elexacaftor–tezacaftor–ivacaftor (ETI), on CFHBI, is still unclear.
Stefanie Diemer   +4 more
wiley   +1 more source

Otolaryngologic Side Effects of GLP‐1 Receptor Agonists

open access: yesThe Laryngoscope, EarlyView.
Objectives With the increasing use of GLP‐1 receptor agonist (GLP‐1 RA) drugs for weight loss and diabetes management, concerns have been raised regarding their potential side effects. We aim to assess the frequency of otolaryngologic adverse events (AEs). Study Design Retrospective analysis of national registry.
Faizaan I. Khan   +11 more
wiley   +1 more source

Development of a Decellularized Urinary Bladder Matrix and Heparin‐Based Cryogel for Promoting Angiogenesis

open access: yesMacromolecular Bioscience, EarlyView.
A dECM‐based cryogel scaffold with sustained VEGF release is developed to promote angiogenesis in ischemic tissues. Fabricated from decellularized porcine urinary bladder matrix and heparin, the scaffold supports VEGF binding and prolonged release. The cryogel demonstrates enhanced angiogenic potential in vitro and in a murine hindlimb ischemia model ...
Dayeon Roo   +7 more
wiley   +1 more source

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